(Q41671941)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366621%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration (English)

1 reference

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8 December 2019

1 reference

1 reference

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8 December 2019

L Mucke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366621%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

T Wyss-Coray

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366621%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

M Buttini

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8 December 2019

S Bellosta

1 reference

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8 December 2019

H Akeefe

1 reference

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8 December 2019

R E Pitas

1 reference

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8 December 2019

R W Mahley

1 reference

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8 December 2019

language of work or name

English

0 references

publication date

1 June 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366621%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

published in

Journal of Neuroscience

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8 December 2019

volume

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8 December 2019

issue

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8 December 2019

page(s)

4867-4880

1 reference

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Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

8 December 2019

cites work

1 reference

12 December 2020

Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study

1 reference

12 December 2020

Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches

1 reference

12 December 2020

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

12 December 2020

Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele

1 reference

12 December 2020

Expression of apolipoprotein E in normal and diverse neurodegenerative disease brain.

1 reference

12 December 2020

Human apolipoprotein E: the Alzheimer's disease connection.

1 reference

12 December 2020

Excitatory amino acids as a final common pathway for neurologic disorders.

1 reference

12 December 2020

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease

1 reference

12 December 2020

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

1 reference

12 December 2020

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

1 reference

12 December 2020

Targeted Replacement of the Mouse Apolipoprotein E Gene with the Common Human APOE3 Allele Enhances Diet-induced Hypercholesterolemia and Atherosclerosis

1 reference

12 December 2020

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

1 reference

12 December 2020

Neurons of the human frontal cortex display apolipoprotein E immunoreactivity: implications for Alzheimer's disease

1 reference

12 December 2020

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

1 reference

12 December 2020

Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation

1 reference

12 December 2020

Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

1 reference

12 December 2020

Selective alterations in the cellular distribution of apolipoprotein E immunoreactivity following transient cerebral ischaemia in the rat

1 reference

12 December 2020

Expression of apolipoprotein E during nerve degeneration and regeneration

1 reference

12 December 2020

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

1 reference

12 December 2020

Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury

1 reference

12 December 2020

Hippocampal damage produced by systemic injections of domoic acid in mice.

1 reference

12 December 2020

Quantitative assessment of the synaptophysin immuno-reactivity of the cortical neuropil in various neurodegenerative disorders with dementia.

1 reference

12 December 2020

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes

1 reference

12 December 2020

Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging

1 reference

12 December 2020

Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

1 reference

12 December 2020

Differential cellular accumulation/retention of apolipoprotein E mediated by cell surface heparan sulfate proteoglycans. Apolipoproteins E3 and E2 greater than e4.

1 reference

12 December 2020

Association of apolipoprotein E polymorphism with outcome after head injury.

1 reference

12 December 2020

Correlations of synaptic and pathological markers with cognition of the elderly

1 reference

12 December 2020

Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease.

1 reference

12 December 2020

Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control

1 reference

12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

12 December 2020

Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms

1 reference

12 December 2020

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets

1 reference

12 December 2020

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

1 reference

12 December 2020

Spectrum of human immunodeficiency virus-associated neocortical damage

1 reference

12 December 2020

Polymorphism of apolipoprotein E and occurrence of dysbetalipoproteinaemia in man

1 reference

12 December 2020

Isolation and characterization of apolipoprotein E

1 reference

12 December 2020

An improved T1/A ribonuclease protection assay.

1 reference

12 December 2020

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

1 reference

12 December 2020

The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization

1 reference

12 December 2020

Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

1 reference

12 December 2020

A Method for Obtaining Cerebrospinal Fluid from Mice

1 reference

12 December 2020

Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice

1 reference

12 December 2020

Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females

1 reference

12 December 2020

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

1 reference

12 December 2020

Behavioural, physiological and morphological analysis of a line of apolipoprotein E knockout mouse

1 reference

12 December 2020

Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease.

1 reference

12 December 2020

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

12 December 2020

Specific regional transcription of apolipoprotein E in human brain neurons

1 reference

12 December 2020

Apolipoprotein E: impact of cytoskeletal stability in neurons and the relationship to Alzheimer's disease.

1 reference

12 December 2020

Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

1 reference

12 December 2020

Excitatory amino acid neurotoxicity and neurodegenerative disease

1 reference

12 December 2020

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

1 reference

12 December 2020

Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease

1 reference

12 December 2020

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

12 December 2020

Indicator expression directed by regulatory sequences of the glial fibrillary acidic protein (GFAP) gene: in vivo comparison of distinct GFAP-lacZ transgenes

1 reference

12 December 2020

Neurodegeneration in the central nervous system of apoE-deficient mice

1 reference

12 December 2020

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

1 reference

12 December 2020

An antibody against phosphorylated neurofilaments identifies a subset of damaged association axons in Alzheimer's disease.

1 reference

12 December 2020

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

1 reference

12 December 2020

Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury

1 reference

12 December 2020

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo.

1 reference

12 December 2020

Complete cerebral ischemia with short-term survival in rat induced by cardiac arrest. II. Extracellular and intracellular accumulation of apolipoproteins E and J in the brain

1 reference

12 December 2020

Amyloid beta-protein, APOE genotype and head injury

1 reference

12 December 2020

Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth

1 reference

12 December 2020

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

1 reference

12 December 2020

Novel role of human CD4 molecule identified in neurodegeneration

1 reference

12 December 2020

High and low annealing temperatures increase both specificity and yield in touchdown and stepdown PCR.

1 reference

12 December 2020

Human apolipoprotein E. The complete amino acid sequence

1 reference

12 December 2020

10.1523/JNEUROSCI.19-12-04867.1999

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366621%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366621%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

10366621

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366621%20AND%20SRC:MED&resulttype=core&format=json