(Q41522331)

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The urokinase-type plasminogen activator system in cancer metastasis: A review

scientific article published on July 3, 1997

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Europe PubMed Central

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2 October 2017

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Europe PubMed Central

The urokinase-type plasminogen activator system in cancer metastasis: a review (English)

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Europe PubMed Central

PubMed publication ID

2 October 2017

The urokinase-type plasminogen activator system in cancer metastasis: A review (English)

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

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based on heuristic

inferred from title

cancer metastasis

1 reference

based on heuristic

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9212216

3 September 2024

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P. A. Andreasen

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9212216

3 September 2024

L. Kjøller

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9212216

3 September 2024

L. Christensen

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9212216

3 September 2024

M. J. Duffy

4

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Europe PubMed Central

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3 September 2024

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1 July 1997

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2 October 2017

3 July 1997

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3 September 2024

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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/%28SICI%291097-0215%2819970703%2972%3A1%3C1%3A%3AAID-IJC1%3E3.0.CO%3B2-Z

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Europe PubMed Central

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3 September 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

https://onlinelibrary.wiley.com/doi/full/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

1 reference

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3 September 2024

International Journal of Cancer

1 reference

Europe PubMed Central

PubMed publication ID

2 October 2017

72

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Europe PubMed Central

PubMed publication ID

2 October 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

2 October 2017

1-22

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Europe PubMed Central

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2 October 2017

Cancer Research

1

54

2372

author name string

Achbarou

publication date

1994

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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Plasminogen activator inhibitors: hormonally regulated serpins

2

1 reference

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Receptor-mediated endocytosis of plasminogen activators and activator/inhibitor complexes

4

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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Production of second messengers following chemotactic and mitogenic urokinase-receptor interaction in human fibroblasts and mouse fibroblasts transfected with human urokinase receptor

5

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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The Very Low Density Lipoprotein Receptor Mediates the Cellular Catabolism of Lipoprotein Lipase and Urokinase-Plasminogen Activator Inhibitor Type I Complexes

7

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Immunoelectron microscopy of the receptor for urokinase plasminogen activator and cathepsin D in the human breast cancer cell line MDA-MB-231.

8

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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Confocal fluorescence microscopy of urokinase plasminogen activator receptor and cathepsin D in human MDA-MB-231 breast cancer cells migrating in reconstituted basement membrane

9

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

Domain interplay in the urokinase receptor. Requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains.

11

1 reference

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The role of cell adhesion molecules in cancer invasion and metastasis

13

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10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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Inhibition of tumor-cell-mediated extracellular matrix destruction by a fibroblast proteinase inhibitor, protease nexin I

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10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

Transformation-dependent activation of urokinase-type plasminogen activator by a plasmin-independent mechanism: involvement of cell surface membranes

15

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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Immunohistochemical localization of the plasminogen activator inhibitor-1 in breast cancer

17

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

Cancer Research

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861

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Bianchi

publication date

1994

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Integrin-dependent induction of functional urokinase receptors in primary T lymphocytes

19

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Prognostic significance of proteolytic enzymes in human brain tumors

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Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes

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10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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Prognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas

24

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

Cancer Research

25

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3043

author name string

Brückner

publication date

1992

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3 September 2024

Activation of pro-urokinase by the human T cell-associated serine proteinase HuTSP-1.

26

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Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator

28

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Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction

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3 September 2024

The receptor for urokinase-type plasminogen activator is not essential for mouse development or fertility

30

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Location of plasminogen activator (PA) and PA inhibitor in human colorectal adenocarcinomas

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Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

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Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells

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Plasminogen-activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells

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Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion

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Physiological consequences of loss of plasminogen activator gene function in mice

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Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis

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Cancer Research

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The Journal of Clinical Endocrinology and Metabolism

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Urokinase-plasminogen-activator levels and prognosis in 69 soft-tissue sarcomas

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3 September 2024

Immunohistochemical localization of urokinase-type plasminogen activator, type-1 plasminogen-activator inhibitor, urokinase receptor and alpha(2)-macroglobulin receptor in human breast carcinomas

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Plasminogen activator inhibitor type I stabilizes vitronectin-dependent adhesions in HT-1080 cells

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Integrins and signal transduction pathways: the road taken

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Regulation of urokinase-type plasminogen activator expression in squamous-cell carcinoma of the oral cavity

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A tetranectin-related protein is produced and deposited in extracellular matrix by human embryonal fibroblasts

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Life at the leading edge: the formation of cell protrusions

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PMA-induced down-regulation of the receptor for alpha 2-macroglobulin in human U937 cells.

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alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor

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Prevention of metastasis by inhibition of the urokinase receptor

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Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor

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Cancer Research

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Urokinase-urokinase receptor interaction: non-mitogenic signal transduction in human epidermal cells.

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Role of specific membrane receptors in urokinase-dependent migration of human keratinocytes

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Modulation of surface-associated urokinase: Binding, interiorization, delivery to lysosomes, and degradation in human keratinocytes

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Selective localization of receptors for urokinase amino-terminal fragment at substratum contact sites of an in vitro-established line of human epidermal cells

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Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

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Generation and characterization of urokinase receptor-deficient mice

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3 September 2024

Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP)

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3 September 2024

Cancer Research

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3 September 2024

Urokinase-plasminogen activator, a marker for aggressive breast carcinomas. Preliminary report

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3 September 2024

Urokinase plasminogen activator as a prognostic marker in different subgroups of patients with breast cancer

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3 September 2024

Cancer Research

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3 September 2024

Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer

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3 September 2024

Interaction of urokinase-type plasminogenactivator (u-PA) with its cellular receptor (u-PAR) induces phosphorylation on tyrosine of a 38 kDa protein

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3 September 2024

Induction of c-fos gene expression by urokinase-type plasminogen activator in human ovarian cancer cells

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3 September 2024

Journal of Biological Chemistry

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3 September 2024

Cellular localisation by in situ hybridisation of cathepsin D, stromelysin 3, and urokinase plasminogen activator RNAs in breast cancer

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3 September 2024

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

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3 September 2024

Urokinase-type plasminogen activator and its receptor: new targets for anti-metastatic therapy?

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3 September 2024

Vitronectin and its receptors

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3 September 2024

Urokinase plasminogen activator, a strong independent prognostic factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay

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3 September 2024

Interaction of urokinase with specific receptors stimulates mobilization of bovine adrenal capillary endothelial cells.

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3 September 2024

Cancer Research

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Cancer Research

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3 September 2024

Plasminogen activator inhibitor-1 and prognosis in primary breast cancer

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3 September 2024

Angiogenesis in cancer, vascular, rheumatoid and other disease

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3 September 2024

Cancer Research

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3 September 2024

Urokinase receptor and colorectal cancer survival.

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3 September 2024

Inside-out integrin signalling

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3 September 2024

Urokinase-dependent adhesion loss and shape change after cyclic adenosine monophosphate elevation in cultured rat mesangial cells

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3 September 2024

High-affinity urokinase receptor antagonists identified with bacteriophage peptide display

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3 September 2024

Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L

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3 September 2024

Cancer Research

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3 September 2024

Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils

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3 September 2024

The urokinase receptor is required for human monocyte chemotaxis in vitro

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3 September 2024

Localization of urokinase-type plasminogen activator receptor on U937 cells: phorbol ester PMA induces heterogeneity

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3 September 2024

Breast cancer angiogenesis: Therapy target and prognostic factor

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3 September 2024

The content of urokinase-type plasminogen activator antigen as a prognostic factor in urinary bladder cancer

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3 September 2024

Growth factor-like effect of urokinase type plasminogen activator in human renal cells

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3 September 2024

Linkage of extracellular plasminogen activator to the fibroblast cytoskeleton: colocalization of cell surface urokinase with vinculin

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3 September 2024

Very Low Density Lipoprotein Receptor Binds and Mediates Endocytosis of Urokinase-type Plasminogen Activator-Type-1 Plasminogen Activator Inhibitor Complex

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3 September 2024

Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: a reference to early systemic disease in solid cancer

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3 September 2024

Cytokeratin 8 released by breast carcinoma cells in vitro binds plasminogen and tissue-type plasminogen activator and promotes plasminogen activation

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3 September 2024

Induced expression of p52(PAI-1) in normal rat kidney cells by the microfilament-disrupting agent cytochalasin D.

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3 September 2024

p52 induction by cytochalasin D in rat kidney fibroblasts: homologies between p52 and plasminogen activator inhibitor type-1

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3 September 2024

Urokinase and macrophages in tumour angiogenesis

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3 September 2024

Clinical relevance of urokinase plasminogen activator, its receptor, and its inhibitor in patients with renal cell carcinoma

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3 September 2024

Cancer Research

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3 September 2024

Integrins: versatility, modulation, and signaling in cell adhesion

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3 September 2024

Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer

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3 September 2024

Expression and localization of elements of the plasminogen activation system in benign breast disease and breast cancers

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3 September 2024

Invasion & Metastasis

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3 September 2024

Lysosomal degradation of receptor-bound urokinase-type plasminogen activator is enhanced by its inhibitors in human trophoblastic choriocarcinoma cells

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3 September 2024

Regulation of urokinase plasminogen activator localization in keratinocytes by calcium ion and E-cadherin

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3 September 2024

The urokinase receptor is a major vitronectin-binding protein on endothelial cells

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3 September 2024

Cancer Research

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3 September 2024

Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain

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3 September 2024

Differential regulation of urokinase-type-1 inhibitor complex endocytosis by phorbol esters in different cell lines is associated with differential regulation of alpha 2-macroglobulin receptor and urokinase receptor expression

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3 September 2024

Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation

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3 September 2024

Effects of urinary trypsin inhibitor on the invasion of reconstituted basement membranes by ovarian cancer cells

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3 September 2024

Cancer Research

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3 September 2024

Inhibition of metastasis of Lewis lung carcinoma by a synthetic peptide within growth factor-like domain of urokinase in the experimental and spontaneous metastasis model

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3 September 2024

Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumor cell invasion in vitro

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3 September 2024

Effects of membrane-associated cathepsin B on the activation of receptor-bound prourokinase and subsequent invasion of reconstituted basement membranes

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3 September 2024

Saturation of tumour cell surface receptors for urokinase-type plasminogen activator by amino-terminal fragment and subsequent effect on reconstituted basement membranes invasion

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3 September 2024

Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion

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3 September 2024

Cancer Research

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3 September 2024

Urokinase-type plasminogen activator enhances invasion of human T cells (Jurkat) into a fibrin matrix.

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3 September 2024

Bovine urokinase-type plasminogen activator and its receptor: cloning and induction by retinoic acid.

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3 September 2024

Two alternatively spliced mouse urokinase receptor mRNAs with different histological localization in the gastrointestinal tract

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3 September 2024

Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma

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3 September 2024

Urokinase (uPA) and PAI-1 predict survival in advanced ovarian cancer patients (FIGO III) after radical surgery and platinum-based chemotherapy

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3 September 2024

Cell migration: a physically integrated molecular process

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3 September 2024

Cancer Research

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3 September 2024

How do cells move along surfaces?

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3 September 2024

Cytoskeletal reorganization and TPA differently modify AP-1 to induce the urokinase-type plasminogen activator gene in LLC-PK1 cells

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3 September 2024

Urokinase-type plasminogen activator-induced monocyte adhesion requires a carboxyl-terminal lysine and cAMP-dependent signal transduction

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3 September 2024

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

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3 September 2024

Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells

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3 September 2024

Regulation of PAI-1 gene expression in vivo

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3 September 2024

Blockage of urokinase receptor reduces in vitro the motility and the deformability of endothelial cells

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3 September 2024

Blockage of the urokinase receptor on the cell surface: construction and characterization of a hybrid protein consisting of the N-terminal fragment of human urokinase and human albumin

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3 September 2024

In vitro anti-proliferative and anti-invasive role of aminoterminal fragment of urokinase-type plasminogen activator on 8701-BC breast cancer cells

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3 September 2024

Systematic mutational analysis of the receptor-binding region of the human urokinase-type plasminogen activator.

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3 September 2024

Tumor necrosis factor and epidermal growth factor modulate migration of human microvascular endothelial cells and production of tissue-type plasminogen activator and its inhibitor

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3 September 2024

Urokinase-type and tissue-type plasminogen activators are essential for in vitro invasion of human melanoma cells

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3 September 2024

Biology and biochemistry of proteinases in tumor invasion.

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3 September 2024

Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade

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3 September 2024

Urokinase plasminogen activator is immunocytochemically detectable in squamous cell but not basal cell carcinomas

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3 September 2024

Cancer Research

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3 September 2024

The alpha 2-macroglobulin receptor and epithelial glycoprotein-330: two giant receptors mediating endocytosis of multiple ligands

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3 September 2024

Cancer Research

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3 September 2024

Proteolysis and invasiveness of brain tumors: role of urokinase-type plasminogen activator receptor

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3 September 2024

Structural requirements for glycosyl-phosphatidylinositol-anchor attachment in the cellular receptor for urokinase plasminogen activator

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3 September 2024

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

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3 September 2024

Phorbol ester induces cultured endothelial cells to invade a fibrin matrix in the presence of fibrinolytic inhibitors.

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3 September 2024

Actin is a surface component of calf pulmonary artery endothelial cells in culture

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3 September 2024

Specific binding of urinary-type plasminogen activator (u-PA) to vitronectin and its role in mediating u-PA-dependent adhesion of U937 cells

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3 September 2024

Overexpression of plasminogen activator inhibitor 2 in human melanoma cells inhibits spontaneous metastasis in scid/scid mice

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3 September 2024

Urokinase-type plasminogen activator and outcome in Dukes' B colorectal cancer

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3 September 2024

Distribution and lateral mobility of the urokinase-receptor complex at the cell surface.

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3 September 2024

Plasminogen activators and their inhibitors in non-small cell lung cancer. Low content of type 2 plasminogen activator inhibitor associated with tumor dissemination

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3 September 2024

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3 September 2024

Localization of urokinase-type plasminogen activator, plasminogen activator inhibitor-1, 2 and plasminogen in colon cancer

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3 September 2024

Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor

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3 September 2024

Tumour-associated proteolytic factors uPA and PAI-1 and survival in totally resected gastric cancer

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3 September 2024

A new low density lipoprotein receptor homologue with 8 ligand binding repeats in brain of chicken and mouse

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3 September 2024

Identification and characterization of urokinase receptors in natural killer cells and T-cell-derived lymphokine activated killer cells

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3 September 2024

Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-beta to TGF-beta

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3 September 2024

Urokinase-type plasminogen activator mediates basic fibroblast growth factor-induced bovine endothelial cell migration independent of its proteolytic activity

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3 September 2024

The two subunits of a phospholipase A2 inhibitor from the plasma of Thailand cobra having structural similarity to urokinase-type plasminogen activator receptor and LY-6 related proteins

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3 September 2024

Expression of urokinase receptor in various stromal-cell populations in human colon cancer: immunoelectron microscopical analysis

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3 September 2024

Cancer Research

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3 September 2024

Migrating vascular smooth muscle cells polarize cell surface urokinase receptors after injury in vitro

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3 September 2024

Angiostatin induces and sustains dormancy of human primary tumors in mice

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3 September 2024

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

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3 September 2024

Coexisting macrophage-associated fibrin formation and tumor cell urokinase in squamous cell and adenocarcinoma of the lung tissues

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3 September 2024

Plasminogen activator dependent pathways in the dissemination of human tumor cells in the chick embryo

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3 September 2024

In vivo invasion of modified chorioallantoic membrane by tumor cells: the role of cell surface-bound urokinase

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3 September 2024

Cancer Research

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3 September 2024

In vivo paracrine interaction between urokinase and its receptor: effect on tumor cell invasion

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3 September 2024

Fibrinolysis associated with oncogenic transformation. Requirement of plasminogen for correlated changes in cellular morphology, colony formation in agar, and cell migration

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3 September 2024

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3 September 2024

Antibodies to plasminogen activator inhibit human tumor metastasis

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3 September 2024

Cancer Research

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3 September 2024

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3 September 2024

A ligand-free, soluble urokinase receptor is present in the ascitic fluid from patients with ovarian cancer.

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3 September 2024

Proteolytic balance and capillary morphogenesis

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3 September 2024

Upregulation of urokinase receptor expression on migrating endothelial cells

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3 September 2024

Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins

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3 September 2024

Ligand interaction between urokinase-type plasminogen activator and its receptor probed with 8-anilino-1-naphthalenesulfonate. Evidence for a hydrophobic binding site exposed only on the intact receptor

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3 September 2024

Chemical modification of the urokinase-type plasminogen activator and its receptor using tetranitromethane. Evidence for the involvement of specific tyrosine residues in both molecules during receptor-ligand interaction

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3 September 2024

Plasminogen receptors in the mediation of pericellular proteolysis

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3 September 2024

Ultrastructural localization of plasma membrane-associated urokinase-type plasminogen activator at focal contacts

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3 September 2024

Distinct localizations of urokinase-type plasminogen activator and its type 1 inhibitor under cultured human fibroblasts and sarcoma cells

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3 September 2024

Prourokinase activation on the surface of human rhabdomyosarcoma cells: localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class 2 plasminogen activator inhibitor

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3 September 2024

An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator

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3 September 2024

Cancer Research

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3 September 2024

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3 September 2024

Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancer

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3 September 2024

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3 September 2024

Plasminogen activators are involved in keratinocyte and fibroblast migration in wounded cultures in vitro

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3 September 2024

Complementation between urokinase-producing and receptor-producing cells in extracellular matrix degradation

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3 September 2024

Metastatic behavior of human melanoma cell lines in nude mice correlates with urokinase-type plasminogen activator, its type-1 inhibitor, and urokinase-mediated matrix degradation

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3 September 2024

An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells

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3 September 2024

Urokinase-type plasminogen activator/type-2 plasminogen-activator inhibitor complexes are not internalized upon binding to the urokinase-type-plasminogen-activator receptor in THP-1 cells. Interaction of urokinase-type plasminogen activator/type-2 p

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3 September 2024

Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel model

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3 September 2024

The role of an enolase-related molecule in plasminogen binding to cells

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3 September 2024

Receptors for plasminogen and t-PA: an update

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3 September 2024

Cancer Research

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3 September 2024

Type-1 plasminogen activator inhibitor in human breast carcinomas

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3 September 2024

Plasmin abrogates alpha v beta 5-mediated adhesion of a human keratinocyte cell line (HaCaT) to vitronectin

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3 September 2024

The role of the urokinase receptor in extracellular matrix degradation by HT29 human colon carcinoma cells

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3 September 2024

Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect

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3 September 2024

Growth factor control of extracellular proteolysis

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3 September 2024

Plasminogen activators and plasminogen activator inhibitors: biochemical aspects

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3 September 2024

Expression of uPA and its receptor by both neoplastic and stromal cells during xenograft invasion

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3 September 2024

Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor

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3 September 2024

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family

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3 September 2024

Cell-associated plasminogen activation: regulation and physiological functions

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3 September 2024

Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity

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3 September 2024

Laminin interacts with plasminogen and its tissue-type activator

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3 September 2024

Disruption of microtubules inhibits the stimulation of tissue plasminogen activator expression and promotes plasminogen activator inhibitor type 1 expression in human endothelial cells

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3 September 2024

Differential protease expression by cutaneous squamous and basal cell carcinomas

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3 September 2024

Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system

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3 September 2024

Insensitivity of laminin degradation directed by receptor bound urokinase to PAI-1 in cultured colon cancer

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3 September 2024

Cancer Research

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3 September 2024

The human integrin alpha 8 beta 1 functions as a receptor for tenascin, fibronectin, and vitronectin

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3 September 2024

The EGF-inducible protein EIP-1 of migrating normal and malignant rat liver epithelial cells is identical to plasminogen activator inhibitor 1 and is a component of the ECM migration tracks

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3 September 2024

Detection of vitronectin mRNA in tissues and cells of the mouse

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3 September 2024

Cancer Research

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3 September 2024

Cancer Research

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3 September 2024

Complex formation of platelet thrombospondin with plasminogen. Modulation of activation by tissue activator

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3 September 2024

The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes

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3 September 2024

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma

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3 September 2024

Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model

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3 September 2024

A cleaved form of the receptor for urokinase-type plasminogen activator in invasive transplanted human and murine tumors

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3 September 2024

Multiparametric Prognostic Evaluation of Biological Factors in Primary Breast Cancer

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3 September 2024

Cancer Research

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3 September 2024

The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin

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10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

The complete amino acid sequence of low molecular mass urokinase from human urine

304

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

What do dysfunctional serpins tell us about molecular mobility and disease?

305

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants

306

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes

307

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Autocrine saturation of pro-urokinase receptors on human A431 cells

308

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Local function of urokinase receptor at the adhesion contact sites of a metastatic tumor cell

310

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

The role of urokinase-type plasminogen activator in aggressive tumor cell behavior

311

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Stromal aspects of breast carcinoma

312

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Bimodal relationship between invasion of the amniotic membrane and plasminogen activator activity

313

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Tumour invasion: effects of cell adhesion and motility

314

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Cell-associated proteases affect tumour cell migration in vitro

315

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

317

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

The plasminogen activator/plasmin system

318

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

Cytokines induce urokinase-dependent adhesion of human myeloid cells. A regulatory role for plasminogen activator inhibitors

321

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Urokinase receptor mediates mechanical force transfer across the cell surface.

322

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

Regulation of integrin function by the urokinase receptor

323

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3 September 2024

Regulation of extracellular matrix degradation by cell-extracellular matrix interactions

325

1 reference

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3 September 2024

Antisense inhibition of urokinase reduces spread of human ovarian cancer in mice

326

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3 September 2024

Recombinant soluble urokinase receptor as a scavenger for urokinase-type plasminogen activator (uPA). Inhibition of proliferation and invasion of human ovarian cancer cells

327

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3 September 2024

The inner world of cell adhesion: integrin cytoplasmic domains

328

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3 September 2024

Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis

332

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10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

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3 September 2024

Cancer Research

334

54

3656

author name string

Yamamoto

publication date

1994

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Cancer Research

335

54

3329

author name string

Yamamoto

publication date

1994

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Cancer Research

336

54

5016

author name string

Yamamoto

publication date

1994

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Prostate-specific antigen activates single-chain urokinase-type plasminogen activator

337

1 reference

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3 September 2024

Cancer Research

338

50

7623

author name string

Yu

publication date

1990

1 reference

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Vitronectin is not essential for normal mammalian development and fertility.

340

1 reference

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https://api.crossref.org/works/10.1002/(SICI)1097-0215(19970703)72:1%3C1::AID-IJC1%3E3.0.CO;2-Z

3 September 2024

Identifiers

10.1002/(SICI)1097-0215(19970703)72:1<1::AID-IJC1>3.0.CO;2-Z

1 reference

Europe PubMed Central

PubMed publication ID

2 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 October 2017

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