(Q41180292)

27 September 2017

title

Altered T cell receptor ligands trigger a subset of early T cell signals (English)

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27 September 2017

Rabinowitz JD

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27 September 2017

Beeson C

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27 September 2017

Wülfing C

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27 September 2017

Tate K

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27 September 2017

Allen PM

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27 September 2017

Davis MM

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27 September 2017

McConnell HM

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27 September 2017

language of work or name

English

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publication date

1 August 1996

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

page(s)

125-135

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Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56 lck

27 September 2017

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Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface

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Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

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Association of CD8 with p56lck is required for early T cell signalling events.

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Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

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The minimal number of class II MHC-antigen complexes needed for T cell activation

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Stimulation of the phosphatidylinositol pathway can induce T-cell activation

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Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen-Reactivity

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Antigen recognition by helper T cells elicits a sequence of distinct changes of their shape and intracellular calcium

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Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

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Antagonism of superantigen-stimulated helper T-cell clones and hybridomas by altered peptide ligand

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Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands

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Correlations between T-cell specificity and the structure of the antigen receptor

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7 January 2021

T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis

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Structures of an MHC class II molecule with covalently bound single peptides

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7 January 2021

Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

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Early signal transduction by the antigen receptor without commitment to T cell activation

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Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

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T cell receptor antagonist peptides induce positive selection

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T cell receptor antagonists and partial agonists

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Specificity and flexibility in thymic selection

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7 January 2021

Signals and signs for lymphocyte responses

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7 January 2021

Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones

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7 January 2021

Helper T-cell development in the absence of CD4-p56 Ick association

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7 January 2021

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CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

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7 January 2021

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

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7 January 2021

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

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Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

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7 January 2021

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7 January 2021

Stimulation of T cells by antigen-presenting cells is kinetically controlled by antigenic peptide binding to major histocompatibility complex class II molecules

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7 January 2021

Kinetic proofreading in T-cell receptor signal transduction

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7 January 2021

Kinetic discrimination in T-cell activation

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7 January 2021

Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling

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7 January 2021

Ca2+ mobilization in physiologically stimulated single T cells gradually increases with peptide concentration (analog signaling).

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7 January 2021

Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events

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7 January 2021

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

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7 January 2021

Activation of CD4+ T cells in the presence of a nondepleting monoclonal antibody to CD4 induces a Th2-type response in vitro

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7 January 2021

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7 January 2021

Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester

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7 January 2021

Endogenous altered peptide ligands can affect peripheral T cell responses

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7 January 2021

GM‐CSF triggers a rapid, glucose dependent extracellular acidification by TF‐1 cells: Evidence for sodium/proton antiporter and PKC mediated activation of acid production

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7 January 2021

Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker

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7 January 2021

Signal transduction by lymphocyte antigen receptors

1 reference

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7 January 2021

Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium

1 reference

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7 January 2021

Calcium dependency of antigen-specific (T3-Ti) and alternative (T11) pathways of human T-cell activation

1 reference

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7 January 2021

Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980489-6

7 January 2021

Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand

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7 January 2021

A kinase-independent function of Lck in potentiating antigen-specific T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980489-6

7 January 2021

Both high and low avidity antibodies to the T cell receptor can have agonist or antagonist activity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980489-6

7 January 2021

Inability of CD8 alpha' polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980489-6

7 January 2021

10.1016/S1074-7613(00)80489-6

Identifiers

DOI

1 reference

27 September 2017

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