(Q41168802)

27 September 2017

title

Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation (English)

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27 September 2017

Darmon AJ

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27 September 2017

Ley TJ

series ordinal

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27 September 2017

Nicholson DW

series ordinal

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27 September 2017

Bleackley RC

series ordinal

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27 September 2017

language of work or name

English

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publication date

1 September 1996

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Journal of Biological Chemistry

27 September 2017

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inferred from page(s)

published in

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27 September 2017

volume

271

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27 September 2017

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27 September 2017

page(s)

21709-21712

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27 September 2017

cites work

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Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes

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A natural killer cell granule protein that induces DNA fragmentation and apoptosis

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Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

21 January 2018

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Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

21 January 2018

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Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

21 January 2018

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Molecular cloning of the interleukin-1 beta converting enzyme

21 January 2018

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

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The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

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Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

21 January 2018

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Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

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Protease activation during apoptosis: death by a thousand cuts?

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Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

21 January 2018

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Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

21 January 2018

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Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases

21 January 2018

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Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases

21 January 2018

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ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis

21 January 2018

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21 January 2018

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

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21 January 2018

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21 January 2018

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Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

21 January 2018

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21 January 2018

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

21 January 2018

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Processing and activation of CMH-1 by granzyme B.

21 January 2018

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Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

21 January 2018

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Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

21 January 2018

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Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

21 January 2018

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A family of serine esterases in lytic granules of cytolytic T lymphocytes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.36.21709

1 reference

27 September 2017

1 reference