(Q41103002)

26 September 2017

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title

Immunodeficiencies caused by genetic defects in protein kinases (English)

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26 September 2017

L D Notarangelo

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26 September 2017

publication date

1 August 1996

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Current Opinion in Immunology

26 September 2017

published in

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26 September 2017

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26 September 2017

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26 September 2017

page(s)

448-453

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Protein tyrosine kinases in the initiation of antigen receptor signaling

26 September 2017

cites work

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7 January 2021

Multiple kinases mediate T-cell-receptor signaling

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7 January 2021

Transmembrane signaling by antigen receptors of B and T lymphocytes

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7 January 2021

Cytokine signaling through nonreceptor protein tyrosine kinases

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7 January 2021

Cytokine receptor signalling

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7 January 2021

What to do at an end: DNA double-strand-break repair

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7 January 2021

Profound block in thymocyte development in mice lacking p56lck

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7 January 2021

T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease

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7 January 2021

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

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7 January 2021

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

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7 January 2021

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

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7 January 2021

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

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7 January 2021

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

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7 January 2021

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

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7 January 2021

Essential role for ZAP-70 in both positive and negative selection of thymocytes

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7 January 2021

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

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7 January 2021

Syk tyrosine kinase required for mouse viability and B-cell development

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7 January 2021

itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2

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7 January 2021

CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

1 reference

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7 January 2021

Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes

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7 January 2021

A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells

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7 January 2021

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

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7 January 2021

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

1 reference

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7 January 2021

Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

STATs: signal transducers and activators of transcription

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7 January 2021

Identification and purification of human Stat proteins activated in response to interleukin-2

1 reference

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7 January 2021

Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15

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7 January 2021

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

1 reference

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7 January 2021

Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes

1 reference

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7 January 2021

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

1 reference

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7 January 2021

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

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7 January 2021

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

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7 January 2021

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

1 reference

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7 January 2021

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

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7 January 2021

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

1 reference

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7 January 2021

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

Defective lymphoid development in mice lacking Jak3

1 reference

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7 January 2021

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

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7 January 2021

Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor

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7 January 2021

The SCID mouse mutant: definition, characterization, and potential uses

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7 January 2021

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

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7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

Severe combined immunodeficiency (SCID) in man: B cell-negative (B-) SCID patients exhibit an irregular recombination pattern at the JH locus

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

Increased radiosensitivity of granulocyte macrophage colony-forming units and skin fibroblasts in human autosomal recessive severe combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980028-8

7 January 2021

10.1016/S0952-7915(96)80028-8

Identifiers

DOI

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26 September 2017

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