(Q41075527)

26 September 2017

title

Discrimination of amino acids mediating Ras binding from noninteracting residues affecting raf activation by double mutant analysis (English)

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26 September 2017

Jaitner BK

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26 September 2017

Becker J

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26 September 2017

Linnemann T

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26 September 2017

Herrmann C

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26 September 2017

Wittinghofer A

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26 September 2017

Block C

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26 September 2017

language of work or name

English

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publication date

1 November 1997

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Journal of Biological Chemistry

26 September 2017

published in

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26 September 2017

volume

272

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26 September 2017

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26 September 2017

page(s)

29927-29933

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The ins and outs of Raf kinases

26 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Complex formation between RAS and RAF and other protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Activation of Raf as a result of recruitment to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Genes for SMA: multum in parvo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

The complexity of Raf-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Chemical shift assignments and folding topology of the Ras-binding domain of human Raf-1 as determined by heteronuclear three-dimensional NMR spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Ras/Rap effector specificity determined by charge reversal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Two distinct Raf domains mediate interaction with Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

A hot spot of binding energy in a hormone-receptor interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

The effector interactions of p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Additivity of mutational effects in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Equilibrium and kinetic measurements reveal rapidly reversible binding of Ras to Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Correlation of two-hybrid affinity data with in vitro measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Improved method for PCR-mediated site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Analysis of the ERK-stimulated ETS transcription factor ER81.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Phosphorylation of Raf by ceramide-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Kinase suppressor of Ras is ceramide-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Crystal structure of the Src family tyrosine kinase Hck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

18 Systematic mutational analyses of protein-protein interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

A general method for polyethylene-glycol-induced genetic transformation of bacteria and yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.47.29927

21 January 2018

Identifiers

DOI

10.1074/JBC.272.47.29927

1 reference

26 September 2017

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