(Q41038516)

25 September 2017

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title

MDM2 function (English)

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Roberto Montes-de-Oca-Luna

25 September 2017

author

series ordinal

object named as

R Montes de Oca Luna

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25 September 2017

G Lozano

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25 September 2017

publication date

1 April 1998

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Biochimica et Biophysica Acta

25 September 2017

published in

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25 September 2017

volume

1377

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25 September 2017

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25 September 2017

page(s)

M55-9

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

25 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Conservation of structural domains and biochemical activities of the MDM2 protein from Xenopus laevis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

The MDM2 oncoprotein binds specifically to RNA through its RING finger domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Mapping of the p53 and mdm-2 Interaction Domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Mdm2 promotes the rapid degradation of p53

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https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.

1 reference

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7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

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7 January 2021

The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

1 reference

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7 January 2021

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

1 reference

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7 January 2021

Mdm-2: "big brother" of p53.

1 reference

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7 January 2021

Molecular characterization of the hdm2-p53 interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

The expression of the MDM2 gene, a p53 binding protein, in thyroid carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

p53 gene mutations and expression of p53 and mdm2 proteins in invasive breast carcinoma. A comparative analysis with clinico-pathological factors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

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7 January 2021

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Repression of p53-mediated transcription by MDM2: a dual mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Physical and functional interaction between wild-type p53 and mdm2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

The organization and expression of the mdm2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900037-1

7 January 2021

10.1016/S0304-419X(97)00037-1

Identifiers

DOI

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25 September 2017

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