(Q40953763)

25 September 2017

title

Poly(ADP-ribose) polymerase: a guardian of the genome that facilitates DNA repair by protecting against DNA recombination (English)

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25 September 2017

Chatterjee S

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25 September 2017

Berger SJ

series ordinal

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25 September 2017

Berger NA

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25 September 2017

publication date

1 March 1999

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Molecular and Cellular Biochemistry

25 September 2017

published in

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25 September 2017

volume

193

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25 September 2017

issue

1-2

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25 September 2017

page(s)

23-30

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Characterization of polymers of adenosine diphosphate ribose generated in vitro and in vivo

25 September 2017

cites work

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12 December 2020

Histone shuttling by poly ADP-ribosylation

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12 December 2020

Mutant cells defective in poly(ADP-ribose) synthesis due to stable alterations in enzyme activity or substrate availability

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12 December 2020

Induction of sister chromatid exchange by 3-aminobenzamide is independent of bromodeoxyuridine

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12 December 2020

Inhibition of gene-specific repair of alkylation damage in cells depleted of poly(ADP-ribose) polymerase

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12 December 2020

Cell cycle perturbations following DNA damage in the presence of ADP-ribosylation inhibitors.

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12 December 2020

Spontaneous and 3-aminobenzamide-induced sister-chromatid exchange frequencies estimated by ring chromosome analysis

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12 December 2020

Disturbances in DNA precursor metabolism associated with exposure to an inhibitor of poly(ADP-ribose) synthetase

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12 December 2020

Different efficiencies of interaction between 3-aminobenzamide and various monofunctional alkylating agents in the induction of sister chromatid exchanges.

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12 December 2020

Poly(ADP-ribose) synthesis is involved in the toxic effects of alkylating agents but does not regulate DNA repair

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12 December 2020

Cell cycle-dependent potentiation of X-ray-induced chromosomal aberrations by 3-aminobenzamide

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12 December 2020

Metabolic consequences of DNA damage: the role of poly (ADP-ribose) polymerase as mediator of the suicide response

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12 December 2020

Dual function for poly(ADP-ribose) synthesis in response to DNA strand breakage

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12 December 2020

Enzymology of ADP-ribose polymer synthesis.

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12 December 2020

Camptothecin hypersensitivity in poly(adenosine diphosphate-ribose) polymerase-deficient cell lines.

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12 December 2020

Molecular and biochemical features of poly (ADP-ribose) metabolism

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12 December 2020

Involvement of Poly (ADP-ribose) in the Radiation Response of Mammalian Cells

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12 December 2020

NAD(+)-dependent repair of damaged DNA by human cell extracts

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12 December 2020

High incidence of sister chromatid exchanges and chromatid interchanges in the conditions of lowered activity of poly(ADP-ribose)polymerase

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12 December 2020

Deletion of transfected oncogenes from NIH 3T3 transformants by inhibitors of poly(ADP-ribose) polymerase

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12 December 2020

ADP-ribosylation of proteins. Enzymology and biological significance.

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12 December 2020

Cellular recovery of dividing and confluent C3H10T1/2 cells from N-methyl-N'-nitro-N-nitrosoguanidine in the presence of ADP-ribosylation inhibitors.

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12 December 2020

Poly(ADP-ribose) in the cellular response to DNA damage

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12 December 2020

Inhibitors of poly(adenosine diphosphate ribose) polymerase induce sister chromatid exchanges

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12 December 2020

Poly(ADP-ribosylation) in vitro. Reaction parameters and enzyme mechanism

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12 December 2020

A shuttle mechanism for DNA-protein interactions. The regulation of poly(ADP-ribose) polymerase

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12 December 2020

Etoposide (VP-16-213)-induced gene alterations: potential contribution to cell death

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12 December 2020

Stimulation of intrachromosomal homologous recombination in mammalian cells by an inhibitor of poly(ADP-ribosylation)

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12 December 2020

Specificity of inhibitors of poly(ADP-ribose) synthesis. Effects on nucleotide metabolism in cultured cells

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12 December 2020

Contribution of incorporated 5-bromodeoxyuridine in DNA to the frequencies of sister-chromatid exchanges induced by inhibitors of poly-(ADP-ribose)-polymerase

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12 December 2020

Growth-phase-dependent response to DNA damage in poly(ADP-ribose) polymerase deficient cell lines: basis for a new hypothesis describing the role of poly(ADP-ribose) polymerase in DNA replication and repair

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12 December 2020

Induction of sister chromatid exchanges by nicotinamide in Chinese hamster lung fibroblasts and human lymphoblastoid cells

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12 December 2020

Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: studies in normal and DNA-repair defective cells

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12 December 2020

A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage

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12 December 2020

3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light

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12 December 2020

Inhibitors of poly(ADP-ribose) polymerase enhance DNA strand breaks, excision repair, and sister chromatid exchanges induced by alkylating agents

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12 December 2020

3-Aminobenzamide is lethal to MMS-damaged human fibroblasts primarily during S phase

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12 December 2020

Strategy for selection of cell variants deficient in poly(ADP-ribose) polymerase

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12 December 2020

Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly(ADP-ribose) polymerase DNA-binding domain in mammalian cells.

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12 December 2020

Role of poly(ADP-ribose) formation in DNA repair

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12 December 2020

Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells

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12 December 2020

Poly(ADP-ribose)polymerase: a perplexing participant in cellular responses to DNA breakage

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12 December 2020

Mechanism of epipodophyllotoxin-induced cell death in poly(adenosine diphosphate-ribose) synthesis-deficient V79 Chinese hamster cell lines.

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12 December 2020

Depletion of nuclear poly(ADP-ribose) polymerase by antisense RNA expression: influences on genomic stability, chromatin organization, and carcinogen cytotoxicity.

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12 December 2020

Poly(ADP-ribose) catabolism in mammalian cells exposed to DNA-damaging agents

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12 December 2020

Hypersensitivity to Clinically Useful Alkylating Agents and Radiation in Poly(ADP-ribose) Polymerase-Deficient Cell Lines

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12 December 2020

Poly(ADP-ribose) polymerase is a catalytic dimer and the automodification reaction is intermolecular

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12 December 2020

Illegitimate and homologous recombination in mammalian cells: differential sensitivity to an inhibitor of poly(ADP-ribosylation).

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12 December 2020

Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences

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12 December 2020

Do inhibitor studies demonstrate a role for poly(ADP-ribose) in DNA repair?

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12 December 2020

Depletion of poly(ADP-ribose) polymerase by antisense RNA expression results in a delay in DNA strand break rejoining.

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12 December 2020

ADP-ribosylation is involved in the integration of foreign DNA into the mammalian cell genome

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12 December 2020

Induction of M(r) 78,000 glucose-regulated stress protein in poly(adenosine diphosphate-ribose) polymerase- and nicotinamide adenine dinucleotide-deficient V79 cell lines and its relation to resistance to the topoisomerase II inhibitor etoposide.

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12 December 2020

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12 December 2020

Effect of inhibitors of poly(ADP-ribose) polymerase on the induction of GRP78 and subsequent development of resistance to etoposide.

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12 December 2020

Regulation of DNA ligase activity by poly(ADP-ribose)

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12 December 2020

Alkylating agent hypersensitivity in poly(adenosine diphosphate-ribose) polymerase deficient cell lines

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12 December 2020

Identifiers

DOI

10.1023/A:1006983304079

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Dimensions Publication ID

25 September 2017

1043910900

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