(Q40939844)

25 September 2017

title

Regulation of AML2/CBFA3 in hematopoietic cells through the retinoic acid receptor alpha-dependent signaling pathway (English)

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25 September 2017

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X F Le

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25 September 2017

Y Groner

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25 September 2017

S M Kornblau

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25 September 2017

Y Gu

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25 September 2017

W N Hittelman

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25 September 2017

D Levanon

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25 September 2017

K Mehta

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25 September 2017

R B Arlinghaus

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25 September 2017

K S Chang

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25 September 2017

language of work or name

English

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publication date

1 July 1999

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Journal of Biological Chemistry

25 September 2017

published in

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25 September 2017

volume

274

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25 September 2017

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25 September 2017

page(s)

21651-21658

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t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

25 September 2017

cites work

1 reference

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AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

21 January 2018

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Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain

21 January 2018

1 reference

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PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21)(q22;q22.3) in acute myelogenous leukemia

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Six distinct nuclear factors interact with the 75-base-pair repeat of the Moloney murine leukemia virus enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Leukaemia/Drosophila homology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

21 January 2018

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Expression of runt in the mouse embryo.

21 January 2018

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Expression of the Runt domain-encoding PEBP2 alpha genes in T cells during thymic development

21 January 2018

1 reference

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The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Increased expression of AML1 during retinoic-acid-induced differentiation of U937 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

1 reference

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

The cDNA cloning of the transcripts of human PEBP2alphaA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Expression of the PEBP2alphaA/AML3/CBFA1 gene is regulated by BMP4/7 heterodimer and its overexpression suppresses type I collagen and osteocalcin gene expression in osteoblastic and nonosteoblastic mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Structural alterations in the transcription factor PEBP2/CBF linked to four different types of leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Identification of a new murine runt domain-containing gene, Cbfa3, and localization of the human homolog, CBFA3, to chromosome 1p35-pter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: interactions with the osteocalcin gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Identification of a receptor for the morphogen retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Nuclear receptor that identifies a novel retinoic acid response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Activation of retinoid X receptors induces apoptosis in HL-60 cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Identification of highly potent retinoic acid receptor alpha-selective antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

The retinoid signaling pathway: molecular and genetic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

PML, a growth suppressor disrupted in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Analysis of the growth and transformation suppressor domains of promyelocytic leukemia gene, PML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Two nuclear signalling pathways for vitamin D

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Mapping of the mouse homolog of the human runt domain gene, AML2, to the distal region of mouse chromosome 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

Acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.31.21651

21 January 2018

Identifiers

DOI

10.1074/JBC.274.31.21651

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25 September 2017

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