(Q40707342)

22 September 2017

title

Inhibition of glioma growth by tumor-specific activation of double-stranded RNA-dependent protein kinase PKR. (English)

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22 September 2017

Alexei Shir

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22 September 2017

Alexander Levitzki

series ordinal

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22 September 2017

publication date

19 August 2002

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

page(s)

895-900

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Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA

22 September 2017

cites work

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PKR, apoptosis and cancer

21 January 2018

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Interactions between double-stranded RNA regulators and the protein kinase DAI

21 January 2018

1 reference

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

21 January 2018

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Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

21 January 2018

1 reference

Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter

21 January 2018

1 reference

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

21 January 2018

1 reference

Mechanism of action of antisense RNA. Sometime inhibition of transcription, processing, transport, or translation

21 January 2018

1 reference

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

The 2-5A system: modulation of viral and cellular processes through acceleration of RNA degradation

21 January 2018

1 reference

Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways.

21 January 2018

1 reference

A diminished activation capacity of the interferon-inducible protein kinase PKR in human T lymphocytes

21 January 2018

1 reference

21 January 2018

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Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes

21 January 2018

1 reference

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

21 January 2018

1 reference

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

21 January 2018

1 reference

Retrovirus producer cells encoding antisense VEGF prolong survival of rats with intracranial GS9L gliomas

21 January 2018

1 reference

Local endostatin treatment of gliomas administered by microencapsulated producer cells

21 January 2018

1 reference

A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR.

21 January 2018

1 reference

7 January 2021

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7 January 2021

2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase both in vitro and in vivo

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7 January 2021

The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

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7 January 2021

Identifiers

DOI

10.1038/NBT730

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22 September 2017

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