(Q40679893)

English

Resistance of p53 knockout cells to doxorubicin is related to reduced formation of DNA strand breaks rather than impaired apoptotic signaling

scientific article published on January 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Resistance of p53 knockout cells to doxorubicin is related to reduced formation of DNA strand breaks rather than impaired apoptotic signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

apoptotic process

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2

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Inga Wedemeyer

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Europe PubMed Central

PubMed publication ID

22 September 2017

author name string

Torsten R Dunkern

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Manuela Baumgärtner

3

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Europe PubMed Central

PubMed publication ID

22 September 2017

Gerhard Fritz

4

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Europe PubMed Central

PubMed publication ID

22 September 2017

Bernd Kaina

5

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Europe PubMed Central

PubMed publication ID

22 September 2017

publication date

1 January 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

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Europe PubMed Central

PubMed publication ID

22 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

1

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Europe PubMed Central

PubMed publication ID

22 September 2017

49-60

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Europe PubMed Central

PubMed publication ID

22 September 2017

Intercalation with DNA is a prerequisite for Daunomycin, Adriamycin and its congeners in inhibiting DNAase I

1 reference

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Doxorubicin inhibits human DNA topoisomerase I

1 reference

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Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

1 reference

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Modulation of DNA topoisomerase II activity and expression in melanoma cells with acquired drug resistance

1 reference

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Anthracycline antibiotics in cancer therapy. Focus on drug resistance

1 reference

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Doxorubicin-induced DNA breaks, topoisomerase II activity and gene expression in human melanoma cells

1 reference

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Reduced topoisomerase II activity in multidrug-resistant human non-small cell lung cancer cell lines

1 reference

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Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

1 reference

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Decreased cytotoxic effects of doxorubicin in a human ovarian cancer-cell line expressing wild-type p53 and WAF1/CIP1 genes.

1 reference

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

1 reference

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Administration of wild-type p53 adenoviral vector synergistically enhances the cytotoxicity of anti-cancer drugs in human lung cancer cells irrespective of the status of p53 gene

1 reference

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based on heuristic

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DNA double-strand breaks trigger apoptosis in p53-deficient fibroblasts

1 reference

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based on heuristic

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A simple technique for quantitation of low levels of DNA damage in individual cells

1 reference

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Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

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Ultraviolet light-induced DNA damage triggers apoptosis in nucleotide excision repair-deficient cells via Bcl-2 decline and caspase-3/-8 activation

1 reference

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based on heuristic

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Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

1 reference

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inferred from DOI database lookup

Identification of a silencer, enhancer, and basal promoter region in the human CD95 (Fas/APO-1) gene

1 reference

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Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells

1 reference

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based on heuristic

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CD95's deadly mission in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900185-4

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-mediated up-regulation of CD95 is not involved in genotoxic drug-induced apoptosis of human breast tumor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900185-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The CD95/CD95 ligand system is not the major effector in anticancer drug-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900185-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy

1 reference

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7 January 2021

based on heuristic

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900185-4

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA double-strand breaks in mammalian cells after exposure to intercalating agents

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900185-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Radiation-induced apoptosis: Relevance to radiotherapy

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900185-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900185-4

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Induction of DNA breaks and apoptosis in crosslink-hypersensitive V79 cells by the cytostatic drug beta-D-glucosyl-ifosfamide mustard

1 reference

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7 January 2021

based on heuristic

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Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Primary mouse fibroblasts deficient for c-Fos, p53 or for both proteins are hypersensitive to UV light and alkylating agent-induced chromosomal breakage and apoptosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of ultraviolet light, methyl methanesulfonate and ionizing radiation on the genotoxic response and apoptosis of mouse fibroblasts lacking c-Fos, p53 or both

1 reference

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7 January 2021

based on heuristic

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Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts

1 reference

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7 January 2021

based on heuristic

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Identifiers

10.1016/S1568-7864(02)00185-4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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