(Q40674172)

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Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing

scientific article published on 29 January 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Cristina Muñoz-Pinedo

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Carmen Palacios

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Abelardo López-Rivas

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

author name string

Carmen Ruiz-Ruiz

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Carmen Ruiz de Almodóvar

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

language of work or name

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publication date

29 January 2003

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

12759-12768

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

The receptor for the cytotoxic ligand TRAIL

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Apoptosis control by death and decoy receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Expression and function of CD95 (FAS/APO-1) in leukaemia-lymphoma tumour lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

The Mitochondrial F0F1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Mitochondrial respiratory chain inhibitors induce apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Aberrant glycolytic metabolism of cancer cells: a remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for type II hexokinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Glucose depletion enhances the anti-tumor effect of TNF.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Bcl-2 overexpression blocks activation of the death protease CPP32/Yama/apopain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Possible mechanisms for tumour cell sensitivity to TNF-alpha and potential therapeutic applications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

The oxidative metabolism of glutamine. A modulator of reactive oxygen intermediate-mediated cytotoxicity of tumor necrosis factor in L929 fibrosarcoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Causes and consequences of tumour acidity and implications for treatment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Metabolic depletion of ATP by fructose inversely controls CD95- and tumor necrosis factor receptor 1-mediated hepatic apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Uncouplers of oxidative phosphorylation can enhance a Fas death signal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

A unique glucose-dependent apoptotic pathway induced by c-Myc

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

The opposing roles of the Akt and c-Myc signalling pathways in survival from CD95-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Phosphorylation of FADD/ MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Stimulation by glucose of cyclic AMP accumulation in mouse pancreatic islets is mediated by protein kinase C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Dealing with energy demand: the AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Regulation of receptor function by cholesterol.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes

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https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

CD40 signaling in human dendritic cells is initiated within membrane rafts

1 reference

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21 January 2018

Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas

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21 January 2018

A matter of life and cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Essential role of active nuclear transport in apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c rel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212392200

21 January 2018

Influence of cycloheximide-mediated downregulation of glucose transport on TNF alpha-induced apoptosis

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21 January 2018

Identifiers

10.1074/JBC.M212392200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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