(Q40611808)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Matt T Bianchi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Robert L Macdonald

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

1 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

published in

Journal of Neuroscience

1 reference

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21 December 2019

volume

1 reference

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21 December 2019

issue

1 reference

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21 December 2019

page(s)

10934-10943

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json

An update on GABAA receptors

21 December 2019

cites work

1 reference

12 December 2020

Residues in transmembrane domains I and II determine gamma-aminobutyric acid type AA receptor subtype-selective antagonism by furosemide

1 reference

12 December 2020

Subunit-selective modulation of GABAA receptors by the non-steroidal anti-inflammatory agent, mefenamic acid

1 reference

12 December 2020

Allosteric control of gating and kinetics at P2X(4) receptor channels

1 reference

12 December 2020

Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

1 reference

12 December 2020

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

1 reference

12 December 2020

Effects of a naturally occurring neurosteroid on GABAA IPSCs during development in rat hippocampal or cerebellar slices.

1 reference

12 December 2020

Propofol increases agonist efficacy at the GABA(A) receptor.

1 reference

12 December 2020

Neurosteroid modulation of GABA IPSCs is phosphorylation dependent.

1 reference

12 December 2020

Allosteric modulators affect the efficacy of partial agonists for recombinant GABA(A) receptors

1 reference

12 December 2020

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

1 reference

12 December 2020

Fundamental gating mechanism of nicotinic receptor channel revealed by mutation causing a congenital myasthenic syndrome

1 reference

12 December 2020

Molecular and neuronal substrate for the selective attenuation of anxiety.

1 reference

12 December 2020

Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons.

1 reference

12 December 2020

Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)beta subunits

1 reference

12 December 2020

Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca2+ channel

1 reference

12 December 2020

Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance

1 reference

12 December 2020

alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential

1 reference

12 December 2020

Mutation of the 9' leucine in the GABA(A) receptor gamma2L subunit produces an apparent decrease in desensitization by stabilizing open states without altering desensitized states

1 reference

12 December 2020

Modulation of GABA(A) receptor channel gating by pentobarbital

1 reference

12 December 2020

Neurosteroids: biochemistry and clinical significance

1 reference

12 December 2020

Tonic and spillover inhibition of granule cells control information flow through cerebellar cortex

1 reference

12 December 2020

Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit.

1 reference

12 December 2020

Tracazolate reveals a novel type of allosteric interaction with recombinant gamma-aminobutyric acid(A) receptors

1 reference

12 December 2020

Receptors with different affinities mediate phasic and tonic GABA(A) conductances in hippocampal neurons.

1 reference

12 December 2020

Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors

1 reference

12 December 2020

Alpha1 and alpha6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABA(A) receptors containing the delta subunit

1 reference

12 December 2020

Conformational switch between slow and fast gating modes: allosteric regulation of voltage sensor mobility in the EAG K+ channel

1 reference

12 December 2020

Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release.

1 reference

12 December 2020

Neurosteroid regulation of GABAA receptor single-channel kinetic properties of mouse spinal cord neurons in culture

1 reference

12 December 2020

1 reference

12 December 2020

Differential responses of expressed recombinant human gamma-aminobutyric acidA receptors to neurosteroids

1 reference

12 December 2020

Multiple gating modes and the effect of modulating factors on the μI sodium channel

1 reference

12 December 2020

Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes

1 reference

12 December 2020

Actions of steroids and bemegride on the GABAA receptor of mouse spinal neurones in culture.

1 reference

12 December 2020

Neurosteroids act on recombinant human GABAA receptors

1 reference

12 December 2020

Pentobarbital and picrotoxin have reciprocal actions on single GABAA receptor channels

1 reference

12 December 2020

Taurine in the central nervous system and the mammalian actions of taurine

1 reference

12 December 2020

Pharmacological evidence for taurine as an inhibitory neurotransmitter in the cerebellum.

1 reference

12 December 2020

In vivo determination of extracellular concentration of amino acids in the rat hippocampus. A method based on brain dialysis and computerized analysis

1 reference

12 December 2020

A steroid anesthetic prolongs inhibitory postsynaptic currents in cultured rat hippocampal neurons

1 reference

12 December 2020

Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists

1 reference

12 December 2020

Characterization of the Binding of the GABA Agonist [3H]Piperidine-4-Sulphonic Acid to Bovine Brain Synaptic Membranes

1 reference

12 December 2020

Piperidine-4-sulphonic acid, a new specific GABA agonist

1 reference

12 December 2020

Neurosteroids and GABAA receptor function.

1 reference

12 December 2020

GABAA receptor channels

1 reference

12 December 2020

The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating

1 reference

12 December 2020

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1 reference

12 December 2020

Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique

1 reference

12 December 2020

Altered prevalence of gating modes in neurotransmitter inhibition of N-type calcium channels.

1 reference

12 December 2020

The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit

1 reference

12 December 2020

Selective reduction of one mode of M-channel gating by muscarine in sympathetic neurons.

1 reference

12 December 2020

Modal shifts in acetylcholine receptor channel gating confer subunit-dependent desensitization

1 reference

12 December 2020

Calcineurin regulates M channel modal gating in sympathetic neurons

1 reference

12 December 2020

Delta subunit inhibits neurosteroid modulation of GABAA receptors

1 reference

12 December 2020

beta-Carboline gamma-aminobutyric acidA receptor inverse agonists modulate gamma-aminobutyric acid via the loreclezole binding site as well as the benzodiazepine site

1 reference

12 December 2020

Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors

1 reference

12 December 2020

Benzodiazepine and barbiturate ligands modulate responses of cultured hippocampal neurones to the GABAA receptor partial agonist, 4-PIOL.

1 reference

12 December 2020

Expression of functional GABAA receptors in transfected L929 cells isolated by immunomagnetic bead separation

1 reference

12 December 2020

Neurosteroid prolongs GABAA channel deactivation by altering kinetics of desensitized states

1 reference

12 December 2020

Multiple modulatory effects of the neuroactive steroid pregnanolone on GABAA receptor in frog pituitary melanotrophs

1 reference

12 December 2020

Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors

1 reference

12 December 2020

Single channel properties of recombinant GABAA receptors containing gamma 2 or delta subtypes expressed with alpha 1 and beta 3 subtypes in mouse L929 cells

1 reference

12 December 2020

The benzodiazepine binding site of GABAA receptors

1 reference

12 December 2020

Modulation of recombination human gamma-aminobutyric acidA receptors by isoflurane: influence of the delta subunit

1 reference

12 December 2020

Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells

1 reference

12 December 2020

Effects of PKC activation and receptor desensitization on neurosteroid modulation of GABA(A) receptors

1 reference

12 December 2020

Mode switching kinetics produced by a naturally occurring mutation in the cytoplasmic loop of the human acetylcholine receptor epsilon subunit

1 reference

12 December 2020

Spillover-mediated transmission at inhibitory synapses promoted by high affinity alpha6 subunit GABA(A) receptors and glomerular geometry

1 reference

12 December 2020

GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts

1 reference

12 December 2020

10.1523/JNEUROSCI.23-34-10934.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

14645489

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14645489%20AND%20SRC:MED&resulttype=core&format=json