(Q40516944)

21 September 2017

title

Hsp90 chaperones wild-type p53 tumor suppressor protein (English)

1 reference

21 September 2017

0 references

Bartosz Wawrzynow

1 reference

21 September 2017

Maciej Zylicz

1 reference

21 September 2017

Dawid Walerych

0 references

Grzegorz Kudla

0 references

Alicja Zylicz

1 reference

21 September 2017

Malgorzata Gutkowska

1 reference

21 September 2017

Lin Muller

1 reference

21 September 2017

Frank W King

1 reference

21 September 2017

Aleksandra Helwak

1 reference

21 September 2017

Joanna Boros

1 reference

21 September 2017

language of work or name

English

0 references

publication date

9 September 2004

1 reference

Journal of Biological Chemistry

21 September 2017

published in

1 reference

21 September 2017

volume

279

1 reference

21 September 2017

1 reference

21 September 2017

page(s)

48836-48845

1 reference

21 September 2017

cites work

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

21 January 2018

p53: good cop/bad cop.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

New approaches to understanding p53 gene tumor mutation spectra

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

The p53 tumour suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Parc: a cytoplasmic anchor for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

The hsp90 chaperone complex regulates intracellular localization of the dioxin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Impairment of p53 acetylation, stability and function by an oncogenic transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Activation and activities of the p53 tumour suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Hsp90: a specialized but essential protein-folding tool

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Hsp70 interactions with the p53 tumour suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Heat-shock protein 90, a chaperone for folding and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Structure and functional relationships of Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Rho-modifying C3-like ADP-ribosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

A role for Hsc70 in regulating nucleocytoplasmic transport of a temperature-sensitive p53 (p53Val-135)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Inhibition of MDM2 by hsp90 contributes to mutant p53 stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Thermodynamic stability of wild-type and mutant p53 core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

p53 contains large unstructured regions in its native state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Phosphorylation and hsp90 binding mediate heat shock stabilization of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

The human DnaJ homologue dj2 facilitates mitochondrial protein import and luciferase refolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Human p53 phosphorylation mimic, S392E, increases nonspecific DNA affinity and thermal stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Hsc70/Hsp40 chaperone system mediates the Hsp90-dependent refolding of firefly luciferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Reciprocal interference between the sequence-specific core and nonspecific C-terminal DNA binding domains of p53: implications for regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Regulation of the specific DNA binding function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

p53 Latency. C-terminal domain prevents binding of p53 core to target but not to nonspecific DNA sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

How p53 binds DNA as a tetramer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

A Nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90. N-terminal nucleotide binding unmasks a C-terminal binding pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Protein folding activity of Hsp70 is modified differentially by the hsp40 co-chaperones Sis1 and Ydj1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Structure of the negative regulatory domain of p53 bound to S100B(betabeta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

NQO1 stabilizes p53 through a distinct pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Divergent effects of ATP on the binding of the DnaK and DnaJ chaperones to each other, or to their various native and denatured protein substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Calf thymus Hsc70 protein protects and reactivates prokaryotic and eukaryotic enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

The Clp ATPases define a novel class of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

Global unfolding of a substrate protein by the Hsp100 chaperone ClpA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407601200

21 January 2018

Identifiers

DOI

10.1074/JBC.M407601200

1 reference

21 September 2017

1 reference