(Q40511488)

English

Inhibition of tumor cell growth by interferon-gamma is mediated by two distinct mechanisms dependent upon oxygen tension: induction of tryptophan degradation and depletion of intracellular nicotinamide adenine dinucleotide

scientific article published on September 1989

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1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Inhibition of tumor cell growth by interferon-gamma is mediated by two distinct mechanisms dependent upon oxygen tension: induction of tryptophan degradation and depletion of intracellular nicotinamide adenine dinucleotide (English)

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Aune TM

1

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Pogue SL

2

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

language of work or name

0 references

publication date

1 September 1989

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

84

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Europe PubMed Central

PMC publication ID

21 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

863-875

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

The cytoskeleton of digitonin-treated rat hepatocytes

1 reference

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22 September 2017

Catalase in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

22 September 2017

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

22 September 2017

Glutathione metabolism as a determinant of therapeutic efficacy: a review

1 reference

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22 September 2017

Induction of pulmonary indoleamine 2,3-dioxygenase by interferon

1 reference

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22 September 2017

An Enzyme-Based Theory of Obligate Anaerobiosis: The Physiological Function of Superoxide Dismutase

1 reference

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22 September 2017

The anti-chlamydial and anti-proliferative activities of recombinant murine interferon-gamma are not dependent on tryptophan concentrations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

22 September 2017

ADP-ribosylation

1 reference

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22 September 2017

Induction of indoleamine 2,3-dioxygenase: a mechanism of the antitumor activity of interferon gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

22 September 2017

Induction of tryptophan catabolism is the mechanism for gamma-interferon-mediated inhibition of intracellular Chlamydia psittaci replication in T24 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

22 September 2017

Gamma-interferon-induced inhibition of the growth of Rickettsia prowazekii in fibroblasts cannot be explained by the degradation of tryptophan or other amino acids

1 reference

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22 September 2017

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes

1 reference

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22 September 2017

Interferons: from virus inhibitor to modulator of amino acid and lipid metabolism

1 reference

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22 September 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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22 September 2017

Generation of superoxide anion as a source of hydrogen peroxide in a reconstituted monooxygenase system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

22 September 2017

Intracellular utilization of superoxide anion by indoleamine 2,3-dioxygenase of rabbit enterocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

22 September 2017

Fractionation of DNA from mammalian cells by alkaline elution

1 reference

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22 September 2017

Recombinant interferon-gamma (immuneron): results of a phase I trial in patients with cancer

1 reference

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25 September 2017

Phase I/II trial of human recombinant interferon gamma in renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

25 September 2017

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

25 September 2017

Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

17 June 2018

Dependence of the in vitro antiproliferative activity of recombinant human gamma-interferon on the concentration of tryptophan in culture media.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

17 June 2018

Metabolic consequences of DNA damage: DNA damage induces alterations in glucose metabolism by activation of poly (ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

17 June 2018

Possible participation of superoxide anion in the intestinal tryptophan 2,3-dioxygenase reaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=329730

20 August 2018

Tumor angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detoxification reactions in isolated hepatocytes. Role of glutathione peroxidase, catalase, and formaldehyde dehydrogenase in reactions relating to N-demethylation by the cytochrome P-450 system

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione depletion sensitizes tumor cells to oxidative cytolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

56 A convenient and rapid cytopathic effect inhibition assay for interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymology of interferon action--a short survey

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assays to measure plasma membrane and cytoskeletal changes in interferon-treated cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADP-ribosyltransferase activity in cultured hepatocytes. Interactions with DNA repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled DNA synthesis in normal human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of altered [ADP-ribose]n metabolism on expression of fetal functions by adult hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of DNA breaks and ADP-ribosyl transferase activity in eukaryotic differentiation demonstrated in human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective modification of glutathione metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen tension regulates the expression of angiogenesis factor by macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

o-Phthaldialdehyde precolumn derivatization and reversed-phase high-performance liquid chromatography of polypeptide hydrolysates and physiological fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

51 Measurement of oxidizing radicals by polymorphonuclear leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidizing radical generation by prostaglandin H synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overview: superoxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

10 Superoxide dismutase assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A semi-automated micro-assay for H2O2 release by human blood monocytes and mouse peritoneal macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of human recombinant alpha-2- and gamma-interferon on the growth of human cell lines from solid tumors and hematologic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of tryptophan degradation in vitro and in vivo: a gamma-interferon-stimulated activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of cellular glutathione by flow cytometry utilizing monochlorobimane: some applications to radiation and drug resistance in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulatory and immunotherapeutic properties of recombinant gamma-interferon and recombinant tumor necrosis factor in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2503544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI114247

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

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