(Q40382136)

English

Genetic knockouts in mice: an update

scientific article published on November 1995

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

1 reference

Europe PubMed Central

Genetic knockouts in mice: an update (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

author name string

B S Shastry

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

publication date

1 November 1995

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

51

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

1028-1039

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy

1 reference

https://api.crossref.org/works/10.1007%2FBF01946911

21 January 2018

A novel nonreceptor tyrosine kinase, Srm: cloning and targeted disruption

1 reference

https://api.crossref.org/works/10.1007%2FBF01946911

21 January 2018

Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

1 reference

https://api.crossref.org/works/10.1007%2FBF01946911

21 January 2018

Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1007%2FBF01946911

21 January 2018

Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic stem cells lacking a functional inhibitory G-protein subunit (alpha i2) produced by gene targeting of both alleles

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitation-contraction uncoupling and muscular degeneration in mice lacking functional skeletal muscle ryanodine-receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An HMG-box-containing T-cell factor required for thymocyte differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative feedback regulation of IgE synthesis by murine CD23.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Introduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted mutation in the col5a2 gene reveals a regulatory role for type V collagen during matrix assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MARCKS deficiency in mice leads to abnormal brain development and perinatal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac malformation in neonatal mice lacking connexin43.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Rab3A in neurotransmitter release

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune function in mice lacking the perforin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological consequences of loss of plasminogen activator gene function in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal long bone growth and development in type X collagen-null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double targeted gene replacement for creating null mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent experiments with MHC knock-out mice: more questions than answers

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene targeting and synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scatter factor/hepatocyte growth factor is essential for liver development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin beta 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The murine N-ras gene is not essential for growth and development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensinogen-deficient mice with hypotension

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altering the genome by homologous recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulation of transgenes by site-specific recombination: use of Cre recombinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted gene replacement.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking vimentin develop and reproduce without an obvious phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two different subunits associate to create isoform-specific platelet-derived growth factor receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of Mash-2 in extraembryonic development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MyoD or Myf-5 is required for the formation of skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degeneration of neural cells in the central nervous system of mice deficient in the gene for the adhesion molecule on Glia, the beta 2 subunit of murine Na,K-ATPase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the apolipoprotein C-III gene in mice results in hypotriglyceridemia and protection from postprandial hypertriglyceridemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altering mice by homologous recombination using embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Creation and phenotypic analysis of alpha-lactalbumin-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E-cadherin null mutant embryos fail to form a trophectoderm epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered inflammatory responses in leukotriene-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redundancies, development and the flow of information

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The helix-loop-helix gene E2A is required for B cell formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene knockouts of c-src, transforming growth factor beta 1, and tenascin suggest superfluous, nonfunctional expression of proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Milk composition and lactation of beta-casein-deficient mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered striatal function in a mutant mouse lacking D1A dopamine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic acid receptor beta 2 (RAR beta 2) null mutant mice appear normal.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate the oocyte zona pellucida and effect fertilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine FGFR-1 is required for early postimplantation growth and axial organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the Hexa gene results in mice with biochemical and pathologic features of Tay-Sachs disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parthenogenetic activation of oocytes in c-mos-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thinking about genetic redundancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of human genetic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoietic development of vav-/- mouse embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for Lim1 in head-organizer function

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HNF-3 beta is essential for node and notochord formation in mouse development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of FGF-4 for postimplantation mouse development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active anaphylaxis in IgE-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function of the retinoic acid receptors (RARs) during development: (I) Craniofacial and skeletal abnormalities in RAR double mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired immune and acute-phase responses in interleukin-6-deficient mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noradrenaline is essential for mouse fetal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the compacted myelin sheath of axons of the central nervous system in proteolipid protein-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene disruption in mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC class I expression in mice lacking the proteasome subunit LMP-7

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeotic transformation of cervical vertebrae in Hoxa-4 mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the CD3 eta locus causes high lethality in mice: modulation of Oct-1 transcription on the opposite strand

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced aggressive behavior in mice lacking 5-HT1B receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombocytopenia in c-mpl-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene targeting and development of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice devoid of interferon regulatory factor 1 (IRF-1) show normal expression of type I interferon genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

More to learn from gene knockouts

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correction of a human beta S-globin gene by gene targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in cellular retinoic acid binding protein II (CRABPII) or in both CRABPI and CRABPII are essentially normal

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ikaros gene is required for the development of all lymphoid lineages

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hox11 controls the genesis of the spleen

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7498440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF01946911

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

release_6ffxlaivqzfgbnz2qk7kesr2oe

1 reference

https://api.fatcat.wiki/v0/release/6ffxlaivqzfgbnz2qk7kesr2oe

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Sitelinks

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