(Q40240405)

18 September 2017

Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA. (English)

1 reference

18 September 2017

Miriam Frieden

1 reference

18 September 2017

Signe M Christensen

1 reference

18 September 2017

Nikolaj D Mikkelsen

1 reference

18 September 2017

Christoph Rosenbohm

1 reference

18 September 2017

Charlotte A Thrue

1 reference

18 September 2017

Majken Westergaard

1 reference

18 September 2017

Henrik F Hansen

1 reference

18 September 2017

Henrik Ørum

1 reference

18 September 2017

Troels Koch

1 reference

18 September 2017

1 November 2003

1 reference

18 September 2017

Nucleic Acids Research

1 reference

18 September 2017

1 reference

18 September 2017

1 reference

18 September 2017

6365-6372

1 reference

alpha-L-LNA (alpha-L-ribo configured locked nucleic acid) recognition of DNA: an NMR spectroscopic study

18 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

Design of antisense oligonucleotides stabilized by locked nucleic acids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

alpha-L-ribo-configured locked nucleic acid (alpha-L-LNA): synthesis and properties

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: conformational tuning and high-affinity recognition of DNA/RNA targets.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

The Eight Stereoisomers of LNA (Locked Nucleic Acid): A Remarkable Family of Strong RNA Binding Molecules We acknowledge the Danish Natural Science Research Council, the Danish Technical Research Council, and Exiqon A/S for financial support. Ms Bri

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

Molecular mechanisms of action of antisense drugs

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

Making drugs out of oligonucleotides: a brief review and perspective

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

Specificity of antisense oligonucleotides in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

Oligonucleotides comprised of alternating 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides and D-2'-deoxyribonucleosides (2'F-ANA/DNA 'altimers') induce efficient RNA cleavage mediated by RNase H.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=275462

The solution structure of a locked nucleic acid (LNA) hybridized to DNA

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14576324

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

α-l-LNA (α-i-riboConfigured Locked Nucleic Acid) Recognition of RNA. A Study by NMR Spectroscopy and Molecular Dynamics Simulations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14576324

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKG820

1 reference

18 September 2017

1 reference

18 September 2017

PubMed publication ID

14576324

1 reference