(Q40060672)

English

Mammalian subtilisin-related proteinases in cleavage activation of the paramyxovirus fusion glycoprotein: superiority of furin/PACE to PC2 or PC1/PC3

scientific article published on November 1, 1992

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Europe PubMed Central

PMC publication ID

17 September 2017

Mammalian subtilisin-related proteinases in cleavage activation of the paramyxovirus fusion glycoprotein: superiority of furin/PACE to PC2 or PC1/PC3 (English)

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1404596

23 September 2022

post-translational protein modification

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1404596

23 September 2022

author name string

B. Gotoh

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1404596

23 September 2022

Y. Ohnishi

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1404596

23 September 2022

N. M. Inocencio

3

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23 September 2022

E. Esaki

4

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23 September 2022

K. Nakayama

5

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23 September 2022

P. J. Barr

6

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23 September 2022

G. Thomas

7

1 reference

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23 September 2022

Y. Nagai

8

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23 September 2022

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publication date

1 November 1992

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17 September 2017

full work available at URL

http://jvi.asm.org/cgi/content/abstract/66/11/6391

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23 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1404596/?tool=EBI

online access status

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1404596

23 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1404596/pdf/?tool=EBI

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23 September 2022

https://europepmc.org/articles/PMC240131

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1404596

23 September 2022

https://europepmc.org/articles/PMC240131?pdf=render

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1404596

23 September 2022

Journal of Virology

1 reference

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17 September 2017

66

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Europe PubMed Central

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17 September 2017

11

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Europe PubMed Central

PMC publication ID

17 September 2017

6391-6397

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

1 reference

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22 September 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

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22 September 2017

Trypsin action on the growth of Sendai virus in tissue culture cells. 3. Structural difference of Sendai viruses grown in eggs and tissue culture cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Intracellular processing of the Newcastle disease virus fusion glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Influenza virus A pathogenicity: the pivotal role of hemagglutinin

1 reference

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22 September 2017

Enzymes required for yeast prohormone processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Quantitative basic residue requirements in the cleavage-activation site of the fusion glycoprotein as a determinant of virulence for Newcastle disease virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

The molecular biology of influenza virus pathogenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Yeast KEX2 genes encodes an endopeptidase homologous to subtilisin-like serine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Molecular biology of Newcastle disease virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Characterization of KEX2-encoded endopeptidase from yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Identification of amino acids relevant to three antigenic determinants on the fusion protein of Newcastle disease virus that are involved in fusion inhibition and neutralization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Sequence of the cDNA encoding rat furin, a possible propeptide-processing endoprotease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Effects of amino acid replacements within the tetrabasic cleavage site on the processing of the human insulin receptor precursor expressed in Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Mammalian subtilisins: the long-sought dibasic processing endoproteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Paramyxovirus tropism dependent on host proteases activating the viral fusion glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Isolation and functional expression of a mammalian prohormone processing enzyme, murine prohormone convertase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Cloning and Functional Expression of a Novel Endoprotease Involved in Prohormone Processing at Dibasic Sites1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

Purification of the fusion protein of Sendai virus: analysis of the NH2-terminal sequence generated during precursor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

22 September 2017

fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

25 September 2017

An endoprotease homologous to the blood clotting factor X as a determinant of viral tropism in chick embryo

1 reference

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25 September 2017

The Spread of a Pathogenic and an Apathogenic Strain of Newcastle Disease Virus in the Chick Embryo as Depending on the Protease Sensitivity of the Virus Glycoproteins

1 reference

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25 September 2017

Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of Avian influenza viruses

1 reference

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17 June 2018

Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive precursor protein of Sendai virus

1 reference

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17 June 2018

Inhibition of the assembly of Newcastle disease virus by monensin

1 reference

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Defective propeptide processing of blood clotting factor IX caused by mutation of arginine to glutamine at position -4.

1 reference

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Newcastle disease virus evolution. II. Lack of gene recombination in generating virulent and avirulent strains

1 reference

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17 June 2018

Intracellular targeting and structural conservation of a prohormone-processing endoprotease

1 reference

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17 June 2018

Antigenic mapping and functional analysis of the F protein of Newcastle disease virus using monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

17 June 2018

Structure and expression of mouse furin, a yeast Kex2-related protease. Lack of processing of coexpressed prorenin in GH4C1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

17 June 2018

Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

17 June 2018

Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

17 June 2018

Primary structure of the virus activating protease from chick embryo. Its identity with the blood clotting factor Xa.

1 reference

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17 June 2018

Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats

1 reference

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17 June 2018

Identification of endoprotease activity in the trans Golgi membranes of rat liver cells that specifically processes in vitro the fusion glycoprotein precursor of virulent Newcastle disease virus

1 reference

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17 June 2018

Functional expression of furin demonstrating its intracellular localization and endoprotease activity for processing of proalbumin and complement pro-C3.

1 reference

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17 June 2018

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease

1 reference

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17 June 2018

Expression of factor X and its significance for the determination of paramyxovirus tropism in the chick embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

17 June 2018

Studies on the assembly of the envelope of Newcastle disease virus

1 reference

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17 June 2018

Proteolytic cleavage of the viral glycoproteins and its significance for the virulence of Newcastle disease virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

17 June 2018

Activation of precursors to both glycoporteins of Newcastle disease virus by proteolytic cleavage

1 reference

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17 June 2018

The structure of the hemagglutinin, a determinant for the pathogenicity of influenza viruses

1 reference

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17 June 2018

The polypeptides of mumps virus and their synthesis in infected chick embryo cells

1 reference

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20 August 2018

Structural comparison of the cleavage-activation site of the fusion glycoprotein between virulent and avirulent strains of Newcastle disease virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240131

20 August 2018

Isolation of factor Xa from chick embryo as the amniotic endoprotease responsible for paramyxovirus activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1404596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/1404596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1404596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A membrane-bound, calcium-dependent protease in yeast alpha-cell cleaving on the carboxyl side of paired basic residues

1 reference

https://pubmed.ncbi.nlm.nih.gov/1404596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence requirements for precursor cleavage within the constitutive secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/1404596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.66.11.6391-6397.1992

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

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