(Q39962406)

15 September 2017

Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry (English)

1 reference

15 September 2017

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David William Andrews

1 reference

15 September 2017

Courtney G Sansam

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Erinn L Soucie

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Linda Z Penn

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Yelena M Janumyan

1 reference

15 September 2017

Anuja Chattopadhyay

1 reference

15 September 2017

Ningli Cheng

1 reference

15 September 2017

C Michael Knudson

1 reference

15 September 2017

Elizabeth Yang

1 reference

15 September 2017

language of work or name

English

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publication date

1 October 2003

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15 September 2017

1 reference

15 September 2017

1 reference

15 September 2017

1 reference

15 September 2017

5459-5470

1 reference

BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Cell metabolism in the regulation of programmed cell death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

BAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Genetic control of cell size

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Coordination of cell growth with cell division

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bax alpha perturbs T cell development and affects cell cycle entry of T cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Simultaneous analysis of cellular RNA and DNA content.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

The super anti-apoptotic factor Bcl-xFNK constructed by disturbing intramolecular polar interactions in rat Bcl-xL.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bcl-2-induced changes in E2F regulatory complexes reveal the potential for integrated cell cycle and cell death functions

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Conversion of Bcl-2 to a Bax-like death effector by caspases

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bax-independent inhibition of apoptosis by Bcl-XL.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bcl-2 delays and alters hepatic carcinogenesis induced by transforming growth factor alpha.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

"Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213787

Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model

20 August 2018

1 reference

12 December 2020

Bcl-2 expression delays hepatocyte cell cycle progression during liver regeneration

1 reference

12 December 2020

Deletion of a nonconserved region of Bcl-2 confers a novel gain of function: suppression of apoptosis with concomitant cell proliferation

1 reference

12 December 2020

Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival

1 reference

12 December 2020

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

1 reference

12 December 2020

Paradoxical inhibition of c-myc-induced carcinogenesis by Bcl-2 in transgenic mice

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG533

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

14532118

1 reference