(Q39593027)

13 September 2017

title

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress (English)

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13 September 2017

Jiri Bartek

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Jiří Lukáš

object named as

Jiri Lukas

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Velibor Savic

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Beate Neumann

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Simon Bekker-Jensen

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Claudia Lukas

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Carsten Doil

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13 September 2017

Ronni Sølvhøj Pedersen

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13 September 2017

Merete Grøfte

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13 September 2017

Kok Lung Chan

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13 September 2017

Ian David Hickson

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13 September 2017

publication date

13 February 2011

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

page(s)

243-253

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DNA damage checkpoints: from initiation to recovery or adaptation

13 September 2017

cites work

1 reference

The DNA damage response: ten years after

21 January 2018

1 reference

The DNA-damage response in human biology and disease

21 January 2018

1 reference

Genome instability: a mechanistic view of its causes and consequences

21 January 2018

1 reference

21 January 2018

Chromosome fragile sites

1 reference

A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability

21 January 2018

1 reference

Flexibility and governance in eukaryotic DNA replication.

21 January 2018

1 reference

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

21 January 2018

1 reference

Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX.

21 January 2018

1 reference

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

21 January 2018

1 reference

Essential global role of CDC14 in DNA synthesis revealed by chromosome underreplication unrecognized by checkpoints in cdc14 mutants

21 January 2018

1 reference

RecQ helicases: multifunctional genome caretakers

21 January 2018

1 reference

PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint

21 January 2018

1 reference

BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges

21 January 2018

1 reference

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

21 January 2018

1 reference

The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities

21 January 2018

1 reference

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

21 January 2018

1 reference

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

21 January 2018

1 reference

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

21 January 2018

1 reference

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

21 January 2018

1 reference

The ATM-mediated DNA-damage response: taking shape.

21 January 2018

1 reference

Maintaining genome stability at the replication fork

21 January 2018

1 reference

ATR: an essential regulator of genome integrity

21 January 2018

1 reference

Chromatin challenges during DNA replication and repair

21 January 2018

1 reference

DNA damage foci in mitosis are devoid of 53BP1.

21 January 2018

1 reference

DNA damage signaling in response to double-strand breaks during mitosis

21 January 2018

1 reference

Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells.

21 January 2018

1 reference

Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis

21 January 2018

1 reference

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

21 January 2018

1 reference

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

21 January 2018

1 reference

BubR1- and Polo-coated DNA tethers facilitate poleward segregation of acentric chromatids

21 January 2018

1 reference

ATM prevents the persistence and propagation of chromosome breaks in lymphocytes

21 January 2018

1 reference

53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination

21 January 2018

1 reference

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

21 January 2018

1 reference

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

21 January 2018

1 reference

H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.

21 January 2018

1 reference

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

21 January 2018

1 reference

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

21 January 2018

1 reference

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

21 January 2018

1 reference

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

21 January 2018

1 reference

An oncogene-induced DNA damage model for cancer development

21 January 2018

1 reference

Signatures of mutation and selection in the cancer genome

21 January 2018

1 reference

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

21 January 2018

1 reference

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

21 January 2018

1 reference

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

21 January 2018

1 reference

Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.

21 January 2018

1 reference

Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses

21 January 2018

1 reference

On the origins of ultra-fine anaphase bridges

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21317883

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21317883

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

53BP1, an activator of ATM in response to DNA damage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21317883

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCB2201

1 reference

13 September 2017

1 reference