(Q39016210)

8 September 2017

title

Specific reactivation of latent HIV-1 with designer zinc-finger transcription factors targeting the HIV-1 5'-LTR promoter (English)

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8 September 2017

P Wang

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8 September 2017

X Qu

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8 September 2017

X Wang

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8 September 2017

X Zhu

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8 September 2017

H Zeng

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8 September 2017

H Chen

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8 September 2017

H Zhu

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8 September 2017

publication date

13 March 2014

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8 September 2017

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8 September 2017

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8 September 2017

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8 September 2017

page(s)

490-495

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The challenge of finding a cure for HIV infection

8 September 2017

cites work

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HIV-1 transcription and latency: an update

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Targeting HIV latency: pharmacologic strategies toward eradication

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The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit

21 January 2018

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Human zinc fingers as building blocks in the construction of artificial transcription factors.

21 January 2018

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Positive and negative regulation of endogenous genes by designed transcription factors

21 January 2018

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Engineering polydactyl zinc-finger transcription factors

21 January 2018

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Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors

21 January 2018

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Design and Development of Artificial Zinc Finger Transcription Factors and Zinc Finger Nucleases to the hTERT Locus

21 January 2018

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Zinc-finger-based artificial transcription factors and their applications

21 January 2018

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Interrogating genomes with combinatorial artificial transcription factor libraries: asking zinc finger questions

21 January 2018

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GAL4-VP16 is an unusually potent transcriptional activator

21 January 2018

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Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

21 January 2018

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Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

21 January 2018

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Krüppel-associated boxes are potent transcriptional repression domains

21 January 2018

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In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation

21 January 2018

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Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

21 January 2018

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Drug discovery with engineered zinc-finger proteins

21 January 2018

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Repression of the HIV-1 5' LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors

21 January 2018

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Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.

21 January 2018

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Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1.

21 January 2018

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Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site

21 January 2018

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HIV-1 Tat protein trans-activates transcription in vitro

21 January 2018

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A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

21 January 2018

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Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat

21 January 2018

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Involvement of histone methyltransferase GLP in HIV-1 latency through catalysis of H3K9 dimethylation

21 January 2018

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Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease

21 January 2018

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Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells

21 January 2018

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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

21 January 2018

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Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB

21 January 2018

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As2O3 synergistically reactivate latent HIV-1 by induction of NF-κB.

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2014.21

21 January 2018

https://api.crossref.org/works/10.1038%2FGT.2014.21

7 January 2021

HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2014.21

Induction of angiogenesis in a mouse model using engineered transcription factors

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FGT.2014.21

21 January 2018

https://api.crossref.org/works/10.1038%2FGT.2014.21

7 January 2021

Cytosine methylation targetted to pre-determined sequences

1 reference

https://api.crossref.org/works/10.1038%2FGT.2014.21

7 January 2021

GILZ expression in human dendritic cells redirects their maturation and prevents antigen-specific T lymphocyte response

1 reference

https://api.crossref.org/works/10.1038%2FGT.2014.21

7 January 2021

Identifiers

DOI

10.1038/GT.2014.21

1 reference

release_n5jvnachxrfovl2d7qugzn4p2y

8 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/n5jvnachxrfovl2d7qugzn4p2y

24 November 2022

mapped directly with Wikidata item

1 reference