(Q38354181)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8702653%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

title

An activating mutation in the ATP binding site of the ABL kinase domain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8702653%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8702653%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

P B Allen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8702653%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

language of work or name

English

0 references

publication date

1 August 1996

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8702653%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 October 2019

published in

1 reference

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17 October 2019

volume

271

1 reference

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17 October 2019

issue

1 reference

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17 October 2019

page(s)

19585-19591

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8702653%20AND%20SRC:MED&resulttype=core&format=json

Oncogenes and signal transduction

17 October 2019

cites work

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21 January 2018

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The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

21 January 2018

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Protein modules and signalling networks

21 January 2018

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Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

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21 January 2018

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Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins

21 January 2018

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Src homology 2 domain as a specificity determinant in the c-Abl-mediated tyrosine phosphorylation of the RNA polymerase II carboxyl-terminal repeated domain

21 January 2018

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Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo

21 January 2018

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Alternative 5' exons in c-abl mRNA.

21 January 2018

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Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

21 January 2018

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The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts

21 January 2018

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Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line

21 January 2018

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Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

21 January 2018

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Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src

21 January 2018

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The carboxy terminus of pp60c-src is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus

21 January 2018

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Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

21 January 2018

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Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

21 January 2018

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Mechanisms of p34cdc2 regulation

21 January 2018

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

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Autocrine stimulation after transfer of the granulocyte/macrophage colony-stimulating factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathway

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

21 January 2018

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Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

21 January 2018

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Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line

21 January 2018

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

21 January 2018

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BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

21 January 2018

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Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins

21 January 2018

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In vivo tyrosine phosphorylations of the abelson virus transforming protein are absent in its normal cellular homolog

21 January 2018

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An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

21 January 2018

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Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms

21 January 2018

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Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor

21 January 2018

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BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

21 January 2018

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Control of M-phase by maturation-promoting factor

21 January 2018

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Cdk inhibitors: on the threshold of checkpoints and development

21 January 2018

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Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential

21 January 2018

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A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

21 January 2018

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BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

21 January 2018

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Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products

21 January 2018

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c-abl has a sequence-specific enhancer binding activity

21 January 2018

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