(Q38302515)

1 September 2017

title

Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase (English)

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1 September 2017

Ning Li

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1 September 2017

Marta Lorinczi

series ordinal

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1 September 2017

Keith Ireton

series ordinal

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1 September 2017

Lisa A Elferink

series ordinal

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1 September 2017

language of work or name

English

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publication date

20 April 2007

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Journal of Biological Chemistry

1 September 2017

published in

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1 September 2017

volume

282

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1 September 2017

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1 September 2017

page(s)

16764-16775

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Met, metastasis, motility and more

1 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M610835200

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The Listeria protein internalin B mimics hepatocyte growth factor-induced receptor trafficking

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Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells

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Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

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Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family

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Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation

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Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

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Somatic mutations lead to an oncogenic deletion of met in lung cancer

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A novel germ line juxtamembrane Met mutation in human gastric cancer

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Grb2 regulates internalization of EGF receptors through clathrin-coated pits

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Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits

21 January 2018

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Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits

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c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

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Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment

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Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

21 January 2018

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Tyrosine kinase receptor indistinguishable from the c-met protein

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

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21 January 2018

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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

21 January 2018

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Viable hypomorphic signaling mutant of the Met receptor reveals a role for hepatocyte growth factor in postnatal cerebellar development

21 January 2018

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Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development

21 January 2018

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grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice

21 January 2018

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Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

21 January 2018

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Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

21 January 2018

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Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

21 January 2018

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Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

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Motogenic and morphogenic activity of epithelial receptor tyrosine kinases

21 January 2018

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The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

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c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination

21 January 2018

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The met receptor degradation pathway: requirement for Lys48-linked polyubiquitin independent of proteasome activity

21 January 2018

1 reference

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InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase

21 January 2018

1 reference

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Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

Redundant roles for Met docking site tyrosines and the Gab1 pleckstrin homology domain in InlB-mediated entry of Listeria monocytogenes

21 January 2018

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InlB: an invasion protein of Listeria monocytogenes with a novel type of surface association.

21 January 2018

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A novel function of InIB from Listeria monocytogenes: activation of NF-kappaB in J774 macrophages.

21 January 2018

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Internalin B activates nuclear factor-kappa B via Ras, phosphoinositide 3-kinase, and Akt.

21 January 2018

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A role for phosphoinositide 3-kinase in bacterial invasion

21 January 2018

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Src phosphorylates Grb2-associated binder 1 upon hepatocyte growth factor stimulation

21 January 2018

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C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

21 January 2018

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Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre

21 January 2018

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Coupling of the Proto-oncogene Product c-Cbl to the Epidermal Growth Factor Receptor

21 January 2018

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Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M610835200

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

Shc mediates ligand-induced internalization of epidermal growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

Interaction of Shc with adaptor protein adaptins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

Escape from Cbl-mediated downregulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610835200

21 January 2018

Identifiers

DOI

10.1074/JBC.M610835200

1 reference

1 September 2017

1 reference