(Q38203104)

30 August 2017

title

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease (English)

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30 August 2017

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Josef Priller

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Marco Prinz

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30 August 2017

language of work or name

English

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publication date

9 April 2014

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Nature Reviews Neuroscience

30 August 2017

published in

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30 August 2017

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30 August 2017

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30 August 2017

page(s)

300-312

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Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

30 August 2017

cites work

1 reference

Development and homeostasis of "resident" myeloid cells: the case of the microglia

31 March 2020

1 reference

Development of monocytes, macrophages, and dendritic cells

31 March 2020

1 reference

Beyond stem cells: self-renewal of differentiated macrophages

31 March 2020

1 reference

Microglia in the CNS: immigrants from another world

31 March 2020

1 reference

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

31 March 2020

1 reference

Studying the mononuclear phagocyte system in the molecular age.

31 March 2020

1 reference

Tissue-resident macrophages

31 March 2020

1 reference

Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS.

31 March 2020

1 reference

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

31 March 2020

1 reference

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

31 March 2020

1 reference

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

31 March 2020

1 reference

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

31 March 2020

1 reference

Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

31 March 2020

1 reference

Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.

31 March 2020

1 reference

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

31 March 2020

1 reference

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

31 March 2020

1 reference

Genetic approaches to study glial cells in the rodent brain.

31 March 2020

1 reference

Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation.

31 March 2020

1 reference

Microglia as modulators of cognition and neuropsychiatric disorders

31 March 2020

1 reference

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

31 March 2020

1 reference

Bone marrow-derived elements in the central nervous system: an immunohistochemical and ultrastructural survey of rat chimeras

31 March 2020

1 reference

Three pathways to mature macrophages in the early mouse yolk sac.

31 March 2020

1 reference

Ontogeny of the hematopoietic system

31 March 2020

1 reference

Microglial progenitors with a high proliferative potential in the embryonic and adult mouse brain

31 March 2020

1 reference

Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain

31 March 2020

1 reference

The distribution of microglia and cell death in the fetal rat forebrain

31 March 2020

1 reference

Turnover of resident microglia in the normal adult mouse brain

31 March 2020

1 reference

Localization of morphologically distinct microglial populations in the developing human fetal brain: implications for ontogeny

31 March 2020

1 reference

Microglia in the cerebral wall of the human telencephalon at second trimester.

31 March 2020

1 reference

Macrophages, microglial cells, and HLA-DR antigens in fetal and infant brain

31 March 2020

1 reference

Early microglial colonization of the human forebrain and possible involvement in periventricular white-matter injury of preterm infants

31 March 2020

1 reference

Factors regulating microglia activation

31 March 2020

1 reference

Microglia and cell death in the developing mouse cerebellum

31 March 2020

1 reference

The origin and cell lineage of microglia: new concepts

31 March 2020

1 reference

Origins and functions of phagocytes in the embryo

31 March 2020

1 reference

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

31 March 2020

1 reference

Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits

31 March 2020

1 reference

Reduced number and altered morphology of microglial cells in colony stimulating factor-1-deficient osteopetrotic op/op mice

31 March 2020

1 reference

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

31 March 2020

1 reference

CSF-1 regulation of the wandering macrophage: complexity in action

31 March 2020

1 reference

The granulocyte-macrophage colony stimulating factors

31 March 2020

1 reference

Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice

31 March 2020

1 reference

A stochastic model of self-renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture

31 March 2020

1 reference

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

31 March 2020

1 reference

Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

31 March 2020

1 reference

Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia

31 March 2020

1 reference

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

31 March 2020

1 reference

Zebrafish early macrophages colonize cephalic mesenchyme and developing brain, retina, and epidermis through a M-CSF receptor-dependent invasive process

31 March 2020

1 reference

Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin

31 March 2020

1 reference

Transcription factors in myeloid development: balancing differentiation with transformation.

31 March 2020

1 reference

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

31 March 2020

1 reference

Regulation of postnatal forebrain amoeboid microglial cell proliferation and development by the transcription factor Runx1.

31 March 2020

1 reference

Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression

31 March 2020

1 reference

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

31 March 2020

1 reference

IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype

31 March 2020

1 reference

Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia

31 March 2020

1 reference

IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS.

31 March 2020

1 reference

Dendritic cell and macrophage heterogeneity in vivo

31 March 2020

1 reference

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

31 March 2020

1 reference

ATP mediates rapid microglial response to local brain injury in vivo

31 March 2020

1 reference

Long-range Ca2+ waves transmit brain-damage signals to microglia

31 March 2020

1 reference

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

31 March 2020

1 reference

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

31 March 2020

1 reference

CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization

31 March 2020

1 reference

Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism

31 March 2020

1 reference

Fibrotic disease and the T(H)1/T(H)2 paradigm

31 March 2020

1 reference

Repertoire of microglial and macrophage responses after spinal cord injury

31 March 2020

1 reference

Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.

31 March 2020

1 reference

Comparison of polarization properties of human adult microglia and blood-derived macrophages

31 March 2020

1 reference

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

31 March 2020

1 reference

Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia.

31 March 2020

1 reference

Microglia/macrophage polarization dynamics in white matter after traumatic brain injury

31 March 2020

1 reference

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation

31 March 2020

1 reference

Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas.

31 March 2020

1 reference

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

31 March 2020

1 reference

Multiple sclerosis and Alzheimer's disease

31 March 2020

1 reference

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

31 March 2020

1 reference

TREM2 Variants in Alzheimer's Disease

31 March 2020

1 reference

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

31 March 2020

1 reference

miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization.

31 March 2020

1 reference

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.

31 March 2020

1 reference

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

31 March 2020

1 reference

Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration.

31 March 2020

1 reference

A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model

31 March 2020

1 reference

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

31 March 2020

1 reference

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

31 March 2020

1 reference

Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice

31 March 2020

1 reference

Comment on "Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice".

31 March 2020

1 reference

Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.

31 March 2020

1 reference

Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals

31 March 2020

1 reference

Synaptic pruning by microglia is necessary for normal brain development

31 March 2020

1 reference

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner

31 March 2020

1 reference

Phagocytic glial cells: sculpting synaptic circuits in the developing nervous system

31 March 2020

1 reference

The microglial sensome revealed by direct RNA sequencing

31 March 2020

1 reference

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

31 March 2020

1 reference

Microglial dysfunction in brain aging and Alzheimer's disease

31 March 2020

1 reference

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

31 March 2020

1 reference

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

31 March 2020

1 reference

Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta

31 March 2020

1 reference

Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement

31 March 2020

1 reference

Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids

31 March 2020

1 reference

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

31 March 2020

1 reference

The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study

31 March 2020

1 reference

Blood monocytes consist of two principal subsets with distinct migratory properties

31 March 2020

1 reference

Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal

31 March 2020

1 reference

Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta.

31 March 2020

1 reference

Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

31 March 2020

1 reference

Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

31 March 2020

1 reference

Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin

31 March 2020

1 reference

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

31 March 2020

1 reference

ApoE promotes the proteolytic degradation of Abeta

31 March 2020

1 reference

Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease

31 March 2020

1 reference

Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology

31 March 2020

1 reference

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

31 March 2020

1 reference

Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia.

31 March 2020

1 reference

Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

31 March 2020

1 reference

Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease

31 March 2020

1 reference

Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease

31 March 2020

1 reference

Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

31 March 2020

1 reference

Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

31 March 2020

1 reference

Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus

31 March 2020

1 reference

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

31 March 2020

1 reference

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

31 March 2020

1 reference

Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis.

31 March 2020

1 reference

Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.

31 March 2020

1 reference

Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice

31 March 2020

1 reference

Early and rapid engraftment of bone marrow-derived microglia in scrapie.

31 March 2020

1 reference

Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia

31 March 2020

1 reference

Differentiation of transplanted bone marrow cells in the adult mouse brain

31 March 2020

1 reference

Neuroectodermal and microglial differentiation of bone marrow cells in the mouse spinal cord and sensory ganglia.

31 March 2020

1 reference

Bone marrow-derived cells that populate the adult mouse brain preserve their hematopoietic identity.

31 March 2020

1 reference

Transformation of donor-derived bone marrow precursors into host microglia during autoimmune CNS inflammation and during the retrograde response to axotomy

31 March 2020

1 reference

Bone marrow transdifferentiation in brain after transplantation: a retrospective study

31 March 2020

1 reference

Male donor-derived cells in the brains of female sex-mismatched bone marrow transplant recipients: a Y-chromosome specific in situ hybridization study

31 March 2020

1 reference

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

31 March 2020

1 reference

Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation

31 March 2020

1 reference

Targeting myeloid cells to the brain using non-myeloablative conditioning

31 March 2020

1 reference

Busulfan conditioning enhances engraftment of hematopoietic donor-derived cells in the brain compared with irradiation

31 March 2020

1 reference

Bone marrow cell recruitment to the brain in the absence of irradiation or parabiosis bias

31 March 2020

1 reference

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

31 March 2020

1 reference

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy

31 March 2020

1 reference

Gene therapy for leukodystrophies

31 March 2020

1 reference

Is microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy?

31 March 2020

1 reference

Onset and progression in inherited ALS determined by motor neurons and microglia

31 March 2020

1 reference

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

31 March 2020

1 reference

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

31 March 2020

1 reference

Hematopoietic origin of pathological grooming in Hoxb8 mutant mice

31 March 2020

1 reference

Mechanisms and therapeutic challenges in autism spectrum disorders: insights from Rett syndrome

31 March 2020

1 reference

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

31 March 2020

1 reference

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages

31 March 2020

1 reference

Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network

31 March 2020

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Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes

31 March 2020

1 reference

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF.

31 March 2020

1 reference

Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin

31 March 2020

1 reference

GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome

31 March 2020

1 reference

IRF8 mutations and human dendritic-cell immunodeficiency

31 March 2020

1 reference

Dendritic cell, monocyte, B and NK lymphoid deficiency defines the lost lineages of a new GATA-2 dependent myelodysplastic syndrome.

31 March 2020

1 reference

Microglia in colony-stimulating factor 1-deficient op/op mice

31 March 2020

1 reference

Cells expressing human glucocerebrosidase from a retroviral vector repopulate macrophages and central nervous system microglia after murine bone marrow transplantation

31 March 2020

1 reference

12 December 2020

Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice

1 reference

12 December 2020

Microglial interactions with synapses are modulated by visual experience

1 reference

12 December 2020

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

1 reference

12 December 2020

Kinetics of central nervous system microglial and macrophage engraftment: analysis using a transgenic bone marrow transplantation model

1 reference

12 December 2020

Radiation bone marrow chimeras as a tool to study microglia turnover in normal brain and inflammation

1 reference

12 December 2020

Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients

1 reference

12 December 2020

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

1 reference

12 December 2020

Colonisation of the developing human brain and spinal cord by microglia: a review

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRN3722

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Dimensions Publication ID

30 August 2017

1008765454

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