(Q38174793)

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Therapeutic targeting of EPH receptors and their ligands

scientific article published on January 2014

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Europe PubMed Central

PubMed publication ID

30 August 2017

Therapeutic targeting of EPH receptors and their ligands (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

author name string

Andrew W Boyd

1

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Perry F Bartlett

2

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Martin Lackmann

3

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

publication date

1 January 2014

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Nature Reviews Drug Discovery

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Europe PubMed Central

PubMed publication ID

30 August 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

39-62

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Eph receptors and ephrins in cancer: bidirectional signalling and beyond

1 reference

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21 January 2018

Eph, a protein family coming of age: more confusion, insight, or complexity?

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21 January 2018

Eph/ephrin signalling and function in oncogenesis: lessons from embryonic development.

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21 January 2018

Non-SH2/PDZ reverse signaling by ephrins

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin signaling in vivo: look both ways

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Concepts and consequences of Eph receptor clustering

1 reference

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21 January 2018

Eph/ephrin signaling: networks.

1 reference

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21 January 2018

Eph/ephrin molecules--a hub for signaling and endocytosis

1 reference

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21 January 2018

Eph-dependent cell-cell adhesion and segregation in development and cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Molecular mechanisms of cell segregation and boundary formation in development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrins and Eph receptors in stem cells and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Control of skeletal patterning by ephrinB1-EphB interactions

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B1 forward and reverse signaling are required during mouse development

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Role of EphA4 and EphrinB3 in local neuronal circuits that control walking

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph/ephrin signaling as a potential therapeutic target after central nervous system injury

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Bidirectional modulation of synaptic functions by Eph/ephrin signaling.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph and ephrin interactions in bone.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph-ephrin signalling in adult tissues and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Paradoxes of the EphB4 receptor in cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph-ephrin bidirectional signaling in physiology and disease

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Silencing of EphA3 through a cis interaction with ephrinA5.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-mediated cis-attenuation of Eph receptor signaling is essential for spinal motor axon guidance.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Coexpressed EphA receptors and ephrin-A ligands mediate opposing actions on growth cone navigation from distinct membrane domains

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB receptor activity suppresses colorectal cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin signalling controls brain size by regulating apoptosis of neural progenitors

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-A2 reverse signaling negatively regulates neural progenitor proliferation and neurogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Dancing with the dead: Eph receptors and their kinase-null partners

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent manner

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Elevated protein tyrosine phosphatase activity provokes Eph/ephrin-facilitated adhesion of pre-B leukemia cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin signaling: One raft to rule them all? One raft to sort them? One raft to spread their call and in signaling bind them?

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Regulation of repulsion versus adhesion by different splice forms of an Eph receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Restriction of receptor movement alters cellular response: physical force sensing by EphA2.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph receptors and ephrins restrict cell intermingling and communication

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Retinal axon response to ephrin-as shows a graded, concentration-dependent transition from growth promotion to inhibition

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-independent regulation of cell substrate adhesion by the EphB4 receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Tissue morphogenesis coupled with cell shape changes

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Neural map specification by gradients

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Axon guidance molecules in vascular patterning

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Bone cell interactions through Eph/ephrin: bone modeling, remodeling and associated diseases

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB4 controls blood vascular morphogenesis during postnatal angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-A3 suppresses Wnt signaling to control retinal stem cell potency

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB signaling controls lineage plasticity of adult neural stem cell niche cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Isolation and in vitro expansion of human colonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EPHA3 as a novel therapeutic target in the hematological malignancies

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Overexpression of the receptor tyrosine kinase EphA4 in human gastric cancers.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Mining the cancer genome uncovers therapeutic activity of EphA7 against lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Expression of Ephb2 and Ephb4 in breast carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Receptor tyrosine kinase EphB4 is a survival factor in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 is a critical oncogene in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB4 promotes or suppresses Ras/MEK/ERK pathway in a context-dependent manner: Implications for EphB4 as a cancer target

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB2 is a prognostic factor in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Complex expression patterns of Eph receptor tyrosine kinases and their ephrin ligands in colorectal carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Effects of cancer-associated EPHA3 mutations on lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB4 expression and biological significance in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Activation of the receptor protein tyrosine kinase EphB4 in endometrial hyperplasia and endometrial carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A conditional feedback loop regulates Ras activity through EphA2.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Downregulation of EphA7 by hypermethylation in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Differential expression of EphA7 receptor tyrosine kinase in gastric carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Aberrant methylation of EphA7 in human prostate cancer and its relation to clinicopathologic features

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The consensus coding sequences of human breast and colorectal cancers

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Somatic mutations affect key pathways in lung adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Exploring the link between germline and somatic genetic alterations in breast carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Cancer somatic mutations disrupt functions of the EphA3 receptor tyrosine kinase through multiple mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Targeting of EPH receptor tyrosine kinases for anticancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Phase 1, open-label study of MEDI-547 in patients with relapsed or refractory solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB2 as a therapeutic antibody drug target for the treatment of colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB2 and EphB4 receptors forward signaling promotes SDF-1-induced endothelial cell chemotaxis and branching remodeling

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Inhibition of tumor growth and angiogenesis by soluble EphB4.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Novel EphB4 monoclonal antibodies modulate angiogenesis and inhibit tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: potential as EphA3-specific tumor-targeting reagents

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB4 promotes site-specific metastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinB2.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The role of Ephs, Ephrins, and growth factors in Kaposi sarcoma and implications of EphrinB2 blockade

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Immunocompetent mouse model of breast cancer for preclinical testing of EphA2-targeted therapy

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Molecular targeting of malignant glioma cells with an EphA2-specific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptors

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Cupredoxin-cancer interrelationship: azurin binding with EphB2, interference in EphB2 tyrosine phosphorylation, and inhibition of cancer growth.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

XL647--a multitargeted tyrosine kinase inhibitor: results of a phase II study in subjects with non-small cell lung cancer who have progressed after responding to treatment with either gefitinib or erlotinib.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Dasatinib: an anti-tumour agent via Src inhibition

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

An efficient rapid system for profiling the cellular activities of molecular libraries.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Crystal structure of the EphA4 protein tyrosine kinase domain in the apo- and dasatinib-bound state

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A phase 2 trial of dasatinib in advanced melanoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 expression is associated with aggressive features in ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Intraperitoneal delivery of liposomal siRNA for therapy of advanced ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Erythropoietin-producing hepatocyte B6 variant-derived peptides with the ability to induce glioma-reactive cytotoxic T lymphocytes in human leukocyte antigen-A2+ glioma patients

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulo

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Kinase inhibitors as potential therapeutics for acute and chronic neurodegenerative conditions

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Roles of Eph receptors and ephrins in the normal and damaged adult CNS.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph receptors and ephrins in neuron-astrocyte communication at synapses

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph receptors at synapses: implications in neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Neuropsin cleaves EphB2 in the amygdala to control anxiety

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Semiquantitative expression analysis of ephrine-receptor tyrosine kinase mRNA's in a rat model of traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Upregulation of EphA4 on astrocytes potentially mediates astrocytic gliosis after cortical lesion in the marmoset monkey

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Expression and activation of EphA4 in the human brain after traumatic injury.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Functional and histological outcome after focal traumatic brain injury is not improved in conditional EphA4 knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Axonal regeneration and lack of astrocytic gliosis in EphA4-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Upregulation of EphA3 receptor after spinal cord injury.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Transection of the adult rat spinal cord upregulates EphB3 receptor and ligand expression

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Accumulation of the inhibitory receptor EphA4 may prevent regeneration of corticospinal tract axons following lesion

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Partial change in EphA4 knockout mouse phenotype: loss of diminished GFAP upregulation following spinal cord injury.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA4 deficient mice maintain astroglial-fibrotic scar formation after spinal cord injury

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Myelin-derived ephrinB3 restricts axonal regeneration and recovery after adult CNS injury.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Acute delivery of EphA4-Fc improves functional recovery after contusive spinal cord injury in rats

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Inhibition of EphA7 up-regulation after spinal cord injury reduces apoptosis and promotes locomotor recovery

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Expression profile and role of EphrinA1 ligand after spinal cord injury

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphBs: an integral link between synaptic function and synaptopathies

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Involvement of the γ-secretase-mediated EphA4 signaling pathway in synaptic pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin A receptors and ligands in lesions and normal-appearing white matter in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA4 receptor tyrosine kinase is a modulator of onset and disease severity of experimental autoimmune encephalomyelitis (EAE)

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Structural, stability, dynamic and binding properties of the ALS-causing T46I mutant of the hVAPB MSP domain as revealed by NMR and MD simulations

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph/Ephrin signaling in injury and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Putative dual role of ephrin-Eph receptor interactions in inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB6-null mutation results in compromised T cell function

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Regulation of angiogenesis by Eph-ephrin interactions

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Receptor tyrosine kinase EphA2 mediates thrombin-induced upregulation of ICAM-1 in endothelial cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Inactivation of EphA2 promotes tight junction formation and impairs angiogenesis in brain endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Evidence that the EphA2 receptor exacerbates ischemic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Upregulation of EphA2 during in vivo and in vitro renal ischemia-reperfusion injury: role of Src kinases.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphA2 receptor mediates increased vascular permeability in lung injury due to viral infection and hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph receptors and ephrin ligands. essential mediators of vascular development.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The platelet P2Y12 receptor contributes to granule secretion through Ephrin A4 receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Enhancement of lymphocyte migration and cytokine production by ephrinB1 system in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Expression of Eph receptors and their ligands, ephrins, during lipopolysaccharide fever in rats

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Expression profiling of the ephrin (EFN) and Eph receptor (EPH) family of genes in atherosclerosis-related human cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph/ephrin signaling in epidermal differentiation and disease

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Critical role of the axonal guidance cue EphrinB2 in lung growth, angiogenesis, and repair.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A relative signalling model for the formation of a topographic neural map.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Bidirectional Eph-ephrin signaling during axon guidance

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

PTP1B regulates Eph receptor function and trafficking

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Regulated cleavage of a contact-mediated axon repellent

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphrinA5 acts as a tumor suppressor in glioma by negative regulation of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphrinA5 suppresses colon cancer development by negatively regulating epidermal growth factor receptor stability

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Cell adhesion and EGFR activation regulate EphA2 expression in cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Eph and NMDA receptors control Ca2+/calmodulin-dependent protein kinase II activation during C. elegans oocyte meiotic maturation.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

PSGL-1-mediated activation of EphB4 increases the proangiogenic potential of endothelial progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

A critical role for the EphA3 receptor tyrosine kinase in heart development

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Crystal structure of an Eph receptor-ephrin complex

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Architecture of Eph receptor clusters

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Structural and functional characterization of an agonistic anti-human EphA2 monoclonal antibody

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Vaccines targeting tumor blood vessel antigens promote CD8(+) T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

21 January 2018

EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas).

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

EphB receptors coordinate migration and proliferation in the intestinal stem cell niche

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Clinicopathological significance and prognostic value of EphA3 and CD133 expression in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Dendritic cell-based vaccines suppress metastatic liver tumor via activation of local innate and acquired immunity

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

In vivo small-animal PET/CT of EphB4 receptors using 64Cu-labeled peptide

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Ephrin-B2 and EphB2 regulation of astrocyte-meningeal fibroblast interactions in response to spinal cord lesions in adult rats.

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CLBL genes

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

The Eph/ephrinB signal balance determines the pattern of T-cell maturation in the thymus

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Intramyocardial administration of chimeric ephrinA1-Fc promotes tissue salvage following myocardial infarction in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Hypoxia up-regulates expression of Eph receptors and ephrins in mouse skin

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

How attraction turns to repulsion

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

EphA2 promotes epithelial-mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Functional ephrin-B2 expression for promotive interaction between arterial and venous vessels in postnatal neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Modulation of ephrinB2 leads to increased angiogenesis in ischemic myocardium and endothelial cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

Ephrin-B1 is a novel specific component of the lateral membrane of the cardiomyocyte and is essential for the stability of cardiac tissue architecture cohesion

1 reference

https://api.crossref.org/works/10.1038%2FNRD4175

31 March 2020

EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a tumor-specific shared antigen derived from an Eph receptor and presented to CD4 T cells on HLA class II molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factor receptors in hematopoietic stem cells: EPH family expression in CD34+ and CD133+ cell populations from mobilized peripheral blood.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ephrins negatively regulate cell proliferation in the epidermis and hair follicle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EphB3 limits the expansion of neural progenitor cells in the subventricular zone by regulating p53 during homeostasis and following traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of EphA3 (Hek) gene promoter: DNA methylation regulates expression in hematopoietic tumor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EphA2 overexpression causes tumorigenesis of mammary epithelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Cbl-dependent EphA2 protein degradation is induced by ligand binding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24378802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NRD4175

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Sitelinks

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