(Q37932423)

25 August 2017

1 reference

title

Delineating HIV-associated neurocognitive disorders using transgenic models: the neuropathogenic actions of Vpr. (English)

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25 August 2017

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25 August 2017

Elizabeth Hui

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25 August 2017

Pornpun Vivithanaporn

series ordinal

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25 August 2017

Shaona Acharjee

series ordinal

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25 August 2017

Maria Polyak

series ordinal

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25 August 2017

publication date

15 September 2011

1 reference

Journal of Neuroimmune Pharmacology

25 August 2017

published in

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25 August 2017

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25 August 2017

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25 August 2017

page(s)

319-331

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HIV-1 viral protein R causes peripheral nervous system injury associated with in vivo neuropathic pain

25 August 2017

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21 January 2018

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HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo

21 January 2018

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Innate immunity and chronic immune activation in HCV/HIV-1 co-infection

21 January 2018

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Managing HIV peripheral neuropathy.

21 January 2018

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21 January 2018

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The neuropathogenesis of AIDS

21 January 2018

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Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

21 January 2018

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Vacuolar myelopathy in transgenic mice expressing human immunodeficiency virus type 1 proteins under the regulation of the myelin basic protein gene promoter

21 January 2018

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Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection

21 January 2018

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The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

HIV-1 Vpr binding to HIV-1 LTR C/EBP cis-acting elements and adjacent regions is sequence-specific.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Immune reconstitution inflammatory syndrome and the central nervous system

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Regulation of neural cell survival by HIV-1 infection.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

HIV-1 Vpr causes neuronal apoptosis and in vivo neurodegeneration.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Neuropathologies in Transgenic Mice Expressing Human Immunodeficiency Virus Type 1 Tat Protein under the Regulation of the Astrocyte-Specific Glial Fibrillary Acidic Protein Promoter and Doxycycline

21 January 2018

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Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1.

21 January 2018

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Human immunodeficiency virus type 1 Vpr inhibits axonal outgrowth through induction of mitochondrial dysfunction.

21 January 2018

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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system

21 January 2018

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Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

The mutation rate of human immunodeficiency virus type 1 is influenced by the vpr gene

21 January 2018

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The interaction of vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 In vivo mutation rate

21 January 2018

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Neurological complications of HIV infection.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

NMR structure of the HIV-1 regulatory protein VPR

21 January 2018

1 reference

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Human immunodeficiency virus type 1 Vpr protein is incorporated into the virion in significantly smaller amounts than gag and is phosphorylated in infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Creative blocks: cell-cycle checkpoints and feedback controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Quantitative structure-activity relationship analysis of combretastatins: a class of novel antimitotic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Lentivirus envelope protein exerts differential neuropathogenic effects depending on the site of expression and target cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Deciphering complex mechanisms in neurodegenerative diseases: the advent of systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase-6 regulates astrocyte survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

The C-terminal proline-rich tail of human immunodeficiency virus type 2 Vpx is necessary for nuclear localization of the viral preintegration complex in nondividing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

An HIV-1 transgenic rat that develops HIV-related pathology and immunologic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Human immunodeficiency virus type 1 Vpr: functions and molecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Cyclin activation of p34cdc2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Human cellular restriction factors that target HIV-1 replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Increased in vivo activation of microglia and astrocytes in the brains of mice transgenic for an infectious R5 human immunodeficiency virus type 1 provirus and for CD4-specific expression of human cyclin T1 in response to stimulation by lipopolysacc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Human immunodeficiency virus type 1 Vpr: oligomerization is an essential feature for its incorporation into virus particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Proteolytic processing of SDF-1alpha reveals a change in receptor specificity mediating HIV-associated neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Hepatitis C virus core protein induces neuroimmune activation and potentiates Human Immunodeficiency Virus-1 neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

NMR structure of the (1-51) N-terminal domain of the HIV-1 regulatory protein Vpr

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Immunodetection of human immunodeficiency virus type 1 (HIV-1) Vpr in brain tissue of HIV-1 encephalitic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Hepatitis C Virus Neuroinvasion: Identification of Infected Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Activation of brain macrophages/microglia cells in hepatitis C infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

CNS inflammation and macrophage/microglial biology associated with HIV-1 infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

From endoplasmic-reticulum stress to the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Vpr-host interactions during HIV-1 viral life cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

HIV-associated neurologic disease incidence changes:: Multicenter AIDS Cohort Study, 1990-1998

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Complex Evolutionary History of Primate LentiviralvprGenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Neuropsychiatric disorders in HIV infection: impact of diagnosis on economic costs of care

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-011-9310-7

Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions

21 January 2018

1 reference

12 December 2020

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

1 reference

12 December 2020

Vpr- and Nef-dependent induction of RANTES/CCL5 in microglial cells

1 reference

12 December 2020

Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B

1 reference

12 December 2020

Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: evidence for a role of the envelope.

1 reference

12 December 2020

Expression of human immunodeficiency virus type 1 in the nervous system of transgenic mice leads to neurological disease

1 reference

12 December 2020

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

12 December 2020

Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differs between demented and nondemented AIDS patients

1 reference

12 December 2020

1 reference

12 December 2020

Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest

1 reference

12 December 2020

NeuroAIDS: an evolving epidemic.

1 reference

12 December 2020

The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle

1 reference

12 December 2020

The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection.

1 reference

12 December 2020

The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles

1 reference

12 December 2020

Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences

1 reference

12 December 2020

Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation.

1 reference

12 December 2020

VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes

1 reference

12 December 2020

The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage

1 reference

12 December 2020

Effects of extracellular human immunodeficiency virus type 1 vpr protein in primary rat cortical cell cultures.

1 reference

12 December 2020

Establishment of a rodent model of HIV-associated sensory neuropathy

1 reference

12 December 2020

A conserved LXXLF sequence is the major determinant in p6gag required for the incorporation of human immunodeficiency virus type 1 Vpr.

1 reference

12 December 2020

The amino-terminal region of Vpr from human immunodeficiency virus type 1 forms ion channels and kills neurons.

1 reference

12 December 2020

10.1007/S11481-011-9310-7

Identifiers

DOI

1 reference

25 August 2017

1 reference