(Q37369481)

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Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.

scientific article published on 17 June 2008

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18588899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I (English)

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9 January 2020

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9 January 2020

Stéphane Larochelle

2

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9 January 2020

Estelle Nicolas

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9 January 2020

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Ellen V Stevens

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9 January 2020

Chao Zhang

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9 January 2020

Kevan M Shokat

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9 January 2020

Robert P Fisher

7

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9 January 2020

Yves Pommier

8

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9 January 2020

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17 June 2008

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9 January 2020

Journal of Molecular Biology

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9 January 2020

381

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9 January 2020

3

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9 January 2020

540-549

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9 January 2020

Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations

1 reference

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Rapid and prolonged stalling of human DNA topoisomerase I in UVA-irradiated genomic areas

1 reference

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Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.

1 reference

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6 September 2017

The effects of camptothecin on RNA polymerase II transcription: roles of DNA topoisomerase I.

1 reference

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6 September 2017

CPD damage recognition by transcribing RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Phosphorylation and functions of the RNA polymerase II CTD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Topoisomerase I inhibitors: camptothecins and beyond

1 reference

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6 September 2017

Breaking barriers to transcription elongation

1 reference

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6 September 2017

Repair of topoisomerase I-mediated DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

When transcription and repair meet: a complex system

1 reference

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6 September 2017

The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs

1 reference

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6 September 2017

Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability

1 reference

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6 September 2017

Transcription arrest at DNA damage sites

1 reference

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6 September 2017

Flavopiridol, an inhibitor of transcription: implications, problems and solutions

1 reference

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6 September 2017

Antiviral activity of CYC202 in HIV-1-infected cells

1 reference

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6 September 2017

Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1).

1 reference

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6 September 2017

Repair of and checkpoint response to topoisomerase I-mediated DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

BRCA1 Associates with Processive RNA Polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Subpathways of nucleotide excision repair and their regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

The problem of hypernegative supercoiling and R-loop formation in transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

When machines get stuck--obstructed RNA polymerase II: displacement, degradation or suicide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Cellular roles of dna topoisomerases: a molecular perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Topoisomerase I-mediated DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Processing of topoisomerase I cleavable complexes into DNA damage by transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Supercoiling of the DNA template during transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Core filaments of the nuclear matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

6 September 2017

Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

14 September 2017

A novel hydrogen peroxide-induced phosphorylation and ubiquitination pathway leading to RNA polymerase II proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

14 September 2017

The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

14 September 2017

Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

28 September 2017

BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

28 September 2017

Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

28 September 2017

Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

26 June 2018

DNA topoisomerase I is involved in both repression and activation of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

26 June 2018

Phosphorylation of the RNA polymerase II largest subunit during heat shock and inhibition of transcription in HeLa cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

26 June 2018

Analysis of topoisomerase I/DNA complexes in patients administered topotecan.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

26 June 2018

Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

26 June 2018

Early effects of topoisomerase I inhibition on RNA polymerase II along transcribed genes in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

2 September 2018

RNA polymerase II blockage by cisplatin-damaged DNA. Stability and polyubiquitylation of stalled polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

2 September 2018

Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

2 September 2018

Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

2 September 2018

Altered serine/arginine-rich protein phosphorylation and exonic enhancer-dependent splicing in Mammalian cells lacking topoisomerase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

2 September 2018

DNA topoisomerase I-mediated nicking of circular duplex DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

2 September 2018

The anti-cancer drug camptothecin inhibits elongation but stimulates initiation of RNA polymerase II transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2754794

2 September 2018

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/18588899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear coupling: RNA processing reaches back to transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/18588899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription - guarding the genome by sensing DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/18588899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation causes a conformational change in the carboxyl-terminal domain of the mouse RNA polymerase II largest subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/18588899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumour drugs impede DNA uncoiling by topoisomerase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/18588899

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JMB.2008.06.028

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18588899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18588899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18588899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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