(Q37112104)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

12 February 2020

main subject

autophagy

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Eric M Wauson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Elma Zaganjor

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

A-Young Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Marcy L Guerra

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Anwesha B Ghosh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Angie L Bookout

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Chris P Chambers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Arif Jivan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Kathleen McGlynn

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Michele R Hutchison

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Ralph J Deberardinis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

6 September 2012

1 reference

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12 February 2020

1 reference

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12 February 2020

volume

1 reference

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12 February 2020

issue

1 reference

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12 February 2020

page(s)

851-862

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

mTOR signaling in disease

12 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Liver autophagy contributes to the maintenance of blood glucose and amino acid levels

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

mTOR: from growth signal integration to cancer, diabetes and ageing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Metabolic and genomic response to dietary isocaloric protein restriction in the rat.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1).

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Mammalian autophagy: core molecular machinery and signaling regulation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Critical roles for the TSC-mTOR pathway in β-cell function

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Molecular mechanisms of mTOR-mediated translational control

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Bidirectional transport of amino acids regulates mTOR and autophagy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Amino acid regulation of TOR complex 1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Different functional roles of T1R subunits in the heteromeric taste receptors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

An amino-acid taste receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Sensors of extracellular nutrients in Saccharomyces cerevisiae

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

A family of candidate taste receptors in human and mouse

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Sweet taste signaling functions as a hypothalamic glucose sensor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Transcriptional control of cystine/glutamate transporter gene by amino acid deprivation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Monocarboxylate transporter (MCT)-1 is up-regulated by PPARalpha

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Glutamatergic regulation of the p70S6 kinase in primary mouse neurons

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

The regulation of hepatic protein synthesis during fasting in the rat.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749915

10.1016/J.MOLCEL.2012.08.001

3 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

22959271

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22959271%20AND%20SRC:MED&resulttype=core&format=json