(Q37109203)

18 August 2017

Germ-line mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein (English)

1 reference

18 August 2017

0 references

tumor suppressor gene

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

TP53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

author

Anne-Lise Børresen-Dale

object named as

Børresen AL

1 reference

18 August 2017

Friend SH

1 reference

18 August 2017

T. Frebourg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

J. Kassel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

K. T. Lam

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

M. A. Gryka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

N. Barbier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

T. I. Andersen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

A. L. Børresen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

S. H. Friend

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

18 October 2022

language of work or name

English

0 references

publication date

1 July 1992

1 reference

18 August 2017

15 July 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1631137

full work available at URL

18 October 2022

https://europepmc.org/articles/PMC49511

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

https://europepmc.org/articles/PMC49511?pdf=render

18 October 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1631137

https://pnas.org/doi/pdf/10.1073/pnas.89.14.6413

18 October 2022

1 reference

Crossref

DOI

10.1073/PNAS.89.14.6413

https://api.crossref.org/works/10.1073/PNAS.89.14.6413

Proceedings of the National Academy of Sciences of the United States of America

18 October 2022

published in

1 reference

18 August 2017

1 reference

18 August 2017

1 reference

18 August 2017

6413-6417

1 reference

Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

The p53 proto-oncogene can act as a suppressor of transformation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

p53 functions as a cell cycle control protein in osteosarcomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Suppression of human colorectal carcinoma cell growth by wild-type p53

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Structural aspects of the p53 protein in relation to gene evolution

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Identification of p53 as a sequence-specific DNA-binding protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

The p53 tumour suppressor gene

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

p53 mutations in human cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Identification of a germ-line mutation in the p53 gene in a patient with an intracranial ependymoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

TP53 tumor suppressor gene: a model for investigating human mutagenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Wild type human p53 is antiproliferative in SV40-transformed hamster cells.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Presence of a potent transcription activating sequence in the p53 protein

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Inherited p53 gene mutations in breast cancer

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Prevalence and spectrum of germline mutations of the p53 gene among patients with sarcoma

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Screening for germ line TP53 mutations in breast cancer patients

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49511

Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms

20 October 2018

1 reference

12 December 2020

A germ line mutation in exon 5 of the p53 gene in an extended cancer family

1 reference

12 December 2020

Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles

1 reference

12 December 2020

Lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells

1 reference

12 December 2020

Extraction of DNA from paraffin blocks for Southern blot analysis

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.89.14.6413

1 reference

release_qhdvf4nqjbatlmelixldoe52f4

18 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qhdvf4nqjbatlmelixldoe52f4

24 November 2022

mapped directly with Wikidata item

1 reference

18 August 2017

1 reference