(Q36875508)

16 August 2017

1 reference

title

The negative regulation of Toll-like receptor and associated pathways (English)

1 reference

16 August 2017

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Tali Lang

1 reference

16 August 2017

Ashley Mansell

series ordinal

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16 August 2017

publication date

10 July 2007

1 reference

Immunology & Cell Biology

16 August 2017

published in

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16 August 2017

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16 August 2017

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16 August 2017

page(s)

425-434

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Pathogen recognition and innate immunity

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Toll-like receptor control of the adaptive immune responses

21 January 2018

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

21 January 2018

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Toll-like receptors and innate immunity.

21 January 2018

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New insights into the regulation of TLR signaling.

21 January 2018

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

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Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4.

21 January 2018

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Toll-like receptors in the pathogenesis of human disease

21 January 2018

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Regulation of mammalian defensin expression by Toll-like receptor-dependent and independent signalling pathways

21 January 2018

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The type II 'decoy' receptor: a novel regulatory pathway for interleukin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Interaction of soluble form of recombinant extracellular TLR4 domain with MD-2 enables lipopolysaccharide binding and attenuates TLR4-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The extracellular toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Signaling through the T1/ST2 molecule is not necessary for Th2 differentiation but is important for the regulation of type 1 responses in nonhealing Leishmania major infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

ST2 suppresses IL-6 production via the inhibition of IkappaB degradation induced by the LPS signal in THP-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

TRAIL-R as a negative regulator of innate immune cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Genetic structure and chromosomal mapping of MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

IRAK-M is a negative regulator of Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Negative regulation of toll-like receptor-mediated signaling by Tollip

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

A family of cytokine-inducible inhibitors of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Structure and function of a new STAT-induced STAT inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Negative regulation of cytokine signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

SOCS: suppressors of cytokine signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

beta-arrestins: traffic cops of cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Expanding roles for beta-arrestins as scaffolds and adapters in GPCR signaling and trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Class I and III phosphatidylinositol 3'-kinase play distinct roles in TLR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

PI3K and negative regulation of TLR signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Aberrant Toll receptor expression and endotoxin hypersensitivity in mice lacking a functional TGF-beta 1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Functions of toll-like receptors: lessons from KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Transcriptional regulation by the phosphorylation-dependent factor CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-alpha-induced apoptosis through down-regulation of p53 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Flightless I homolog negatively modulates the TLR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

21 January 2018

MAP kinase phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The function of mitogen-activated protein kinase phosphatase-1 in peptidoglycan-stimulated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Essential role of MAPK phosphatase-1 in the negative control of innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The role of ubiquitination in Drosophila innate immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Mycobacteria target DC-SIGN to suppress dendritic cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

Pathogens target DC-SIGN to influence their fate DC-SIGN functions as a pathogen receptor with broad specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

Innate immune recognition and control of adaptive immune responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

ST2: marker, activator and regulator of Th2 immunity?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

Inhibition of TLR-4/MD-2 signaling by RP105/MD-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

Antisense IRAK-2 oligonucleotide blocks IL-1-stimulated NF-kappaB activation and ICAM-1 expression in cultured endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

DisSARMing Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

SOCS-1 participates in negative regulation of LPS responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

Chronic intrathecal morphine administration produces homologous mu receptor/G-protein desensitization specifically in spinal cord

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

G protein-coupled receptor kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

Two novel genes FIND and LIND differentially expressed in deactivated and Listeria-infected human macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

Dual specificity phosphatases: a gene family for control of MAP kinase function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100094

7 January 2021

Identifiers

DOI

10.1038/SJ.ICB.7100094

1 reference

Dimensions Publication ID

16 August 2017

1006714185

0 references

1 reference