(Q36829275)

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Cofilin-mediated neurodegeneration in Alzheimer's disease and other amyloidopathies

scientific article published on February 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

1 reference

Europe PubMed Central

Cofilin-mediated neurodegeneration in Alzheimer's disease and other amyloidopathies (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

Alzheimer's disease

0 references

neurodegeneration

1 reference

based on heuristic

inferred from title

author name string

Michael T Maloney

1

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

James R Bamburg

2

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

publication date

1 February 2007

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

Molecular Neurobiology

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

35

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

21-44

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Intracellular A beta 1-42 aggregates stimulate the accumulation of stable, insoluble amyloidogenic fragments of the amyloid precursor protein in transfected cells.

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Alzheimer's presenile dementia, senile dementia of Alzheimer type and Down's syndrome in middle age form an age related continuum of pathological changes

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Amyloid β accumulation in axons after traumatic brain injury in humans

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Statin blocks Rho/Rho-kinase signalling and disrupts the actin cytoskeleton: relationship to enhancement of LPS-mediated nitric oxide synthesis in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Mitochondria in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FBF02700622

21 January 2018

Characterization of neuronal dystrophy induced by fibrillar amyloid beta: implications for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho proteins: linking signaling with membrane trafficking

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia signaling to genes: significance in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic genes expressed in Alzheimer's disease brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel actin cytoskeleton: actin tubules

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased Neuronal Endocytosis and Protease Delivery to Early Endosomes in Sporadic Alzheimer’s Disease: Neuropathologic Evidence for a Mechanism of Increased β-Amyloidogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear actin bundles in Amoeba, Dictyostelium and human HeLa cells induced by dimethyl sulfoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linking molecular motors to Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The actin cytoskeleton in ageing and apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paxillin and focal adhesion signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The voltage-dependent anion channel: an essential player in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial translocation of cofilin is an early step in apoptosis induction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-amyloid-related proteins presenilin 1 and BACE1 are axonally transported to nerve terminals in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein precursor accumulates in swollen neurites throughout rat brain with aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The branch point enzyme of the mevalonate pathway for protein prenylation is overexpressed in the ob/ob mouse and induced by adipogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative effects of cofilin (ADF) on actin structure suggest allosteric mechanism of cofilin function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cofilin phosphatases and regulation of actin dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the interactions of actin depolymerizing factor with G- and F-actin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histological Changes induced in Sympathetic, Motor, and Sensory Nerve Cells by Functional Activity (Preliminary note)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Live dynamics of Dictyostelium cofilin suggests a role in remodeling actin latticework into bundles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of rat brain mitochondrial voltage-dependent anion as a potential tool to control leakage of cytochrome c.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegenerative stimuli induce persistent ADF/cofilin-actin rods that disrupt distal neurite function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methodological variables in the assessment of beta amyloid neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actin-ATP hydrolysis is a major energy drain for neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer disease: plaques, tangles, and the basal forebrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-terminal fragments of amyloid-beta peptide cause cholinergic axonal degeneration by a toxic effect rather than by physical injury in the nondemented human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of synaptic proteins in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colocalization of ADF and cofilin in intranuclear actin rods of cultured muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent roles of GSK3 and CDK5 in APP processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma lipids and cholesterol esterification in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin-1 and the amyloid precursor protein are transported bidirectionally in the sciatic nerve of adult rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of LIM kinase 1 renders resistance to apoptosis in PC12 cells by inhibition of caspase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dephosphorylation of cofilin accompanies heat shock-induced nuclear accumulation of cofilin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant activation of focal adhesion proteins mediates fibrillar amyloid beta-induced neuronal dystrophy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated ageing or selective neuronal loss as an important cause of dementia?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for actin in aging and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of calcipressin1, an inhibitor of the phosphatase calcineurin, is altered with aging and Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cofilin expression induces cofilin-actin rod formation and disrupts synaptic structure and function in Aplysia synapses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-secretase-cleaved amyloid precursor protein accumulates at actin inclusions induced in neurons by stress or amyloid beta: a feedforward mechanism for Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bridging cognition, the brain and molecular genetics: evidence from Williams syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADF/cofilin and actin dynamics in disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal membrane cholesterol loss enhances amyloid peptide generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate toxicity in chronic neurodegenerative disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor signaling, neuroprotection, and neural repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways towards and away from Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic slaughter in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for the actin cytoskeleton in cell death and aging in yeast.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria take center stage in aging and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble beta-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock induction of intranuclear actin rods in cultured mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The KKRKK sequence is involved in heat shock-induced nuclear translocation of the 18-kDa actin-binding protein, cofilin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cofilin is a component of intranuclear and cytoplasmic actin rods induced in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of cholesterol in the biosynthesis of beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of Ser-3 of cofilin regulates its essential function on actin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative proteomic analysis of mitochondria from primary neuron cultures treated with amyloid beta peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of the nucleus basalis in Down's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamic acid and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular mechanisms for amyloid beta-protein activation of rat cholinergic basal forebrain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-regulated signaling pathways: role in amyloid beta-induced synaptic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mapping of Alzheimer-type dementia in Down's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins cause intracellular accumulation of amyloid precursor protein, beta-secretase-cleaved fragments, and amyloid beta-peptide via an isoprenoid-dependent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate and Amyloid β-Protein Rapidly Inhibit Fast Axonal Transport in Cultured Rat Hippocampal Neurons by Different Mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol depletion with physiological concentrations of a statin decreases the formation of the Alzheimer amyloid Abeta peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cofilin Changes the Twist of F-Actin: Implications for Actin Filament Dynamics and Cellular Function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial abnormalities in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Rho and Rac signaling to the actin cytoskeleton by paxillin during Drosophila development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoprenoids and Alzheimer's disease: a complex relationship

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF02700622

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

ResearchGate publication ID

0 references

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