(Q36796913)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Differences in regulation of Drosophila and vertebrate integrin affinity by talin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Teresa L Helsten

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Thomas A Bunch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Hisashi Kato

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Jun Yamanouchi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sharon H Choi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Alison L Jannuzi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Mark H Ginsberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Danny L Brower

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sanford J Shattil

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

publication date

28 May 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

Molecular Biology of the Cell

8 January 2020

published in

1 reference

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8 January 2020

volume

1 reference

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8 January 2020

issue

1 reference

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8 January 2020

page(s)

3589-3598

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

Mutations in the Drosophila alphaPS2 integrin subunit uncover new features of adhesion site assembly

8 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Structural basis of integrin activation by talin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Integrin-actin interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Functional and structural correlations of individual alphaIIbbeta3 molecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Integrins: dynamic scaffolds for adhesion and signaling in platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Talin controls integrin activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Src kinase activation by direct interaction with the integrin β cytoplasmic domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

A functional genomic analysis of cell morphology using RNA interference

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Platelets with wings: the maturation of Drosophila integrin biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Structural determinants of integrin recognition by talin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Integrins: bidirectional, allosteric signaling machines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Disruption of C-terminal cytoplasmic domain of betaPS integrin subunit has dominant negative properties in developing Drosophila.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

The phosphotyrosine binding-like domain of talin activates integrins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Disruption of the talin gene arrests mouse development at the gastrulation stage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

The evolution of cell adhesion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Invertebrate integrins: structure, function, and evolution.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Splice variants of the Drosophila PS2 integrins differentially interact with RGD-containing fragments of the extracellular proteins tiggrin, ten-m, and D-laminin 2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Monoclonal antibodies recognizing the N- and C-terminal regions of talin disrupt actin stress fibers when microinjected into human fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Integrin cytoplasmic domains mediate inside-out signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Talin is essential for integrin function in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

A unique talin homologue with a villin headpiece-like domain is required for multicellular morphogenesis in Dictyostelium

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Modulation of integrin activity is vital for morphogenesis

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Functional Properties of Alternatively Spliced Forms of theDrosophilaPS2 Integrin α Subunit

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Determinants of specificity of a baculovirus-expressed antibody Fab fragment that binds selectively to the activated form of integrin alpha IIb beta 3.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Developmentally regulated alternative splicing of Drosophila integrin PS2 alpha transcripts.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Platelet glycoprotein IIb-IIIa (alpha IIb beta 3 integrin) confers fibrinogen- and activation-dependent aggregation on heterologous cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Drosophila PS2 integrin mediates RGD-dependent cell-matrix interactions

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Multiple factors contribute to integrin-talin interactions in vivo.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Amino acid changes in Drosophila alphaPS2betaPS integrins that affect ligand affinity

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Gene duplication and functional divergence during evolution of the cytoskeletal linker protein talin.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Talin loss-of-function uncovers roles in cell contractility and migration in C. elegans

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Activation of integrin alphaIIbbeta3 by modulation of transmembrane helix associations

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

RNA interference of gene expression (RNAi) in cultured Drosophila cells.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Tiggrin, a novel Drosophila extracellular matrix protein that functions as a ligand for Drosophila alpha PS2 beta PS integrins

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488300

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation

5 September 2018

1 reference

12 December 2020

Microinjection of antibodies against talin inhibits the spreading and migration of fibroblasts

1 reference

12 December 2020

Modulation of ligand binding by alternative splicing of the alphaPS2 integrin subunit

1 reference

12 December 2020

Down regulation of talin alters cell adhesion and the processing of the alpha 5 beta 1 integrin

1 reference

12 December 2020

Direct binding of the platelet integrin alphaIIbbeta3 (GPIIb-IIIa) to talin. Evidence that interaction is mediated through the cytoplasmic domains of both alphaIIb and beta3

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E08-01-0085

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

18508915

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18508915%20AND%20SRC:MED&resulttype=core&format=json