(Q36538095)

14 August 2017

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title

Aptamers come of age - at last (English)

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14 August 2017

Peter G Stockley

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author name string

David H J Bunka

series ordinal

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14 August 2017

language of work or name

English

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publication date

1 August 2006

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Nature Reviews Microbiology

14 August 2017

published in

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14 August 2017

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14 August 2017

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14 August 2017

page(s)

588-596

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Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

14 August 2017

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31 March 2020

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New treatments for age-related macular degeneration

31 March 2020

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A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165

31 March 2020

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Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

31 March 2020

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Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX

31 March 2020

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The limits of specificity: an experimental analysis with RNA aptamers to MS2 coat protein variants

31 March 2020

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Crystal structures of a series of RNA aptamers complexed to the same protein target

31 March 2020

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Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution

31 March 2020

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In vitro evolution of the DNA binding sites of Escherichia coli methionine repressor, MetJ.

31 March 2020

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Specific binding of aminoglycoside antibiotics to RNA.

31 March 2020

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In vitro selection and characterization of RNAs with high affinity to antibiotics

31 March 2020

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Solution structure of the tobramycin-RNA aptamer complex

31 March 2020

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Encapsulating streptomycin within a small 40-mer RNA

31 March 2020

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Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation

31 March 2020

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Neutralization of Infectivity of Diverse R5 Clinical Isolates of Human Immunodeficiency Virus Type 1 by gp120-Binding 2′F-RNA Aptamers

31 March 2020

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Selection of RNA aptamers against human influenza virus hemagglutinin using surface plasmon resonance

31 March 2020

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Nonequilibrium capillary electrophoresis of equilibrium mixtures: a universal tool for development of aptamers.

31 March 2020

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Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes

31 March 2020

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Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance

31 March 2020

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Evolution of a T7 RNA polymerase variant that transcribes 2'-O-methyl RNA.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1458

New NTP analogs: the synthesis of 4'-thioUTP and 4'-thioCTP and their utility for SELEX

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1458

Mirror-image RNA that binds D-adenosine

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1458

Liposome-anchored vascular endothelial growth factor aptamers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain

31 March 2020

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Conjugation to polyethylene glycol polymer promotes aptamer biodistribution to healthy and inflamed tissues

31 March 2020

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Association of antisense oligonucleotides with lipoproteins prolongs the plasma half-life and modifies the tissue distribution

31 March 2020

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Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Generation of species cross-reactive aptamers using "toggle" SELEX.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Short bioactive Spiegelmers to migraine-associated calcitonin gene-related peptide rapidly identified by a novel approach: tailored-SELEX

31 March 2020

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Diagnostic potential of PhotoSELEX-evolved ssDNA aptamers

31 March 2020

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A DNA aptamer as a new target-specific chiral selector for HPLC.

31 March 2020

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Separation of nontarget compounds by DNA aptamers

31 March 2020

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An improved method for the in vitro evolution of aptamers and applications in protein detection and purification

31 March 2020

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RNA aptamers as pathway-specific MAP kinase inhibitors

31 March 2020

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Controlling protein activity with ligand-regulated RNA aptamers

31 March 2020

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RNA aptamers as reversible antagonists of coagulation factor IXa.

31 March 2020

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Light regulation of aptamer activity: an anti-thrombin aptamer with caged thymidine nucleobases

31 March 2020

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In vitro evolution of RNA aptamers recognizing carcinogenic aromatic amines

31 March 2020

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Modular aptameric sensors

31 March 2020

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The use of aptamers in large arrays for molecular diagnostics

31 March 2020

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Production and processing of aptamer microarrays

31 March 2020

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Aptamer-derived nucleic acid oligos: applications to develop nucleic acid chips to analyze proteins and small ligands

31 March 2020

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Fast colorimetric sensing of adenosine and cocaine based on a general sensor design involving aptamers and nanoparticles

31 March 2020

1 reference

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Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

31 March 2020

1 reference

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Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase

31 March 2020

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Fusigenic viral liposome for gene therapy in cardiovascular diseases

31 March 2020

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Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

31 March 2020

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Endogenous expression of a high-affinity pseudoknot RNA aptamer suppresses replication of HIV-1.

31 March 2020

1 reference

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Expression of small, therapeutic RNAs in human cell nuclei.

31 March 2020

1 reference

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Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Inhibition of receptor binding by high-affinity RNA ligands to vascular endothelial growth factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Nucleic acid aptamers in cancer medicine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Selection of RNA aptamers to the Alzheimer's disease amyloid peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Structural determinants of conformationally selective, prion-binding aptamers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

HIV-1 inactivation by nucleic acid aptamers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Inhibition of HIV-1 reverse transcriptase by RNA aptamers in Escherichia coli.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Isolation of high-affinity RNA ligands to HIV-1 integrase from a random pool

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

An aptamer that neutralizes R5 strains of human immunodeficiency virus type 1 blocks gp120-CCR5 interaction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Isolation of specific and high-affinity RNA aptamers against NS3 helicase domain of hepatitis C virus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

In vitro selection of RNA aptamers against the HCV NS3 helicase domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

An RNA ligand inhibits hepatitis C virus NS3 protease and helicase activities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Selection of DNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus and inhibit viral RNA synthesis in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Interfering with hepatitis C virus IRES activity using RNA molecules identified by a novel in vitro selection method.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

In vitro selection of novel RNA ligands that bind human cytomegalovirus and block viral infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Controlling gene expression in living cells through small molecule-RNA interactions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Engineering regulatory RNAs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

An RNA thermosensor controls expression of virulence genes in Listeria monocytogenes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Control of gene expression by a natural metabolite-responsive ribozyme

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Exogenous control of mammalian gene expression through modulation of RNA self-cleavage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Group I aptazymes as genetic regulatory switches

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Engineered riboregulators enable post-transcriptional control of gene expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Predicting candidate genomic sequences that correspond to synthetic functional RNA motifs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Genetic screens and selections for small molecules based on a synthetic riboswitch that activates protein translation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1458

31 March 2020

Identifiers

DOI

10.1038/NRMICRO1458

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14 August 2017

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