(Q36528528)

14 August 2017

1 reference

title

Intracellular pattern recognition receptors in the host response (English)

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pattern recognition receptors

14 August 2017

main subject

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1 reference

Etienne Meylan

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Michael Karin

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14 August 2017

Jürg Tschopp

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14 August 2017

language of work or name

English

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publication date

1 July 2006

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14 August 2017

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14 August 2017

volume

442

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14 August 2017

issue

7098

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14 August 2017

page(s)

39-44

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Innate immune recognition

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer

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7 January 2021

Toll-like receptors and innate immunity

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7 January 2021

Toll-like receptor signalling

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7 January 2021

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

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https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

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7 January 2021

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

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https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

CATERPILLER: a novel gene family important in immunity, cell death, and diseases

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https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

NLRs join TLRs as innate sensors of pathogens

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https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Plant innate immunity - direct and indirect recognition of general and specific pathogen-associated molecules.

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7 January 2021

Structure of the apoptotic protease-activating factor 1 bound to ADP

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7 January 2021

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

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https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

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https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Inflammatory Bowel Disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Expression of interleukin 1 beta and interleukin 1 beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

NOD2 and Crohn's disease: loss or gain of function?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations

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https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Tolerance, danger, and the extended family

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Molecular identification of a danger signal that alerts the immune system to dying cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Increased mature interleukin-1beta (IL-1beta) secretion from THP-1 cells induced by nigericin is a result of activation of p45 IL-1beta-converting enzyme processing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

P2X7 receptors regulate NKT cells in autoimmune hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Genetic clues to understanding periodic fevers, and possible therapies

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Blocking IL-1 in systemic inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Interleukin-1-receptor antagonist in the Muckle-Wells syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Naip5/Birc1e and susceptibility to Legionella pneumophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Does Toll-like receptor 3 play a biological role in virus infections?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Antiviral actions of interferons

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Cell type-specific involvement of RIG-I in antiviral response

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

VISA is an adapter protein required for virus-triggered IFN-beta signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

The specific and essential role of MAVS in antiviral innate immune responses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn’s disease patients

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04946

7 January 2021

Identifiers

DOI

10.1038/NATURE04946

1 reference

14 August 2017

1 reference