(Q36506367)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

review article

1 reference

title

Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Ingo Bechmann

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

publication date

14 June 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Medicine

30 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

532-543

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

Self-tolerance in the immune privileged CNS: lessons from the entorhinal cortex lesion model.

30 January 2020

cites work

1 reference

12 December 2020

Resident and infiltrating central nervous system APCs regulate the emergence and resolution of experimental autoimmune encephalomyelitis

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12 December 2020

Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.

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12 December 2020

Dendritic cells: specialized and regulated antigen processing machines

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12 December 2020

Characterization and distribution of phagocytic macrophages in multiple sclerosis plaques

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12 December 2020

Hyperinducibility of Ia antigen on astrocytes correlates with strain-specific susceptibility to experimental autoimmune encephalomyelitis

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12 December 2020

Are astrocytes central players in the pathophysiology of multiple sclerosis?

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12 December 2020

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

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12 December 2020

Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro

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12 December 2020

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

1 reference

12 December 2020

Local enhancement of major histocompatibility complex (MHC) class I and II expression and cell infiltration in experimental allergic encephalomyelitis around axotomized motor neurons

1 reference

12 December 2020

Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain

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12 December 2020

Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS.

1 reference

12 December 2020

HLA class II molecules (HLA-DR, -DP, -DQ) on cells in the human CNS studied in situ and in vitro

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12 December 2020

Initiation of immune responses in brain is promoted by local dendritic cells

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12 December 2020

Presence of B7--2 (CD86) and lack of B7--1 (CD(80) on myelin phagocytosing MHC-II-positive rat microglia is associated with nondestructive immunity in vivo.

1 reference

12 December 2020

Microglia in degenerative neurological disease.

1 reference

12 December 2020

Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system

1 reference

12 December 2020

Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation

1 reference

12 December 2020

Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

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12 December 2020

Myelin basic protein in CSF as indicator of disease activity in multiple sclerosis

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12 December 2020

Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial-derived cytokine IL-1.

1 reference

12 December 2020

Transfer of central nervous system autoantigens and presentation in secondary lymphoid organs

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12 December 2020

Immune function of astrocytes

1 reference

12 December 2020

Mature microglia resemble immature antigen-presenting cells

1 reference

12 December 2020

Defining antigen-dependent stages of T cell migration from the blood to the central nervous system parenchyma

1 reference

12 December 2020

Systemic Immune Deviation in the Brain That Does Not Depend on the Integrity of the Blood-Brain Barrier

1 reference

12 December 2020

Lymphocyte targeting of the brain in adoptive transfer cryolesion-EAE.

1 reference

12 December 2020

Peripheral T cell tolerance

1 reference

12 December 2020

FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier

1 reference

12 December 2020

Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Multiple sclerosis: presence of lymphatic capillaries and lymphoid tissue in the brain and spinal cord

1 reference

12 December 2020

Multiple sclerosis: oligodendrocytes in active lesions do not express class II major histocompatibility complex molecules.

1 reference

12 December 2020

Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system

1 reference

12 December 2020

Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations

1 reference

12 December 2020

Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: membrane currents

1 reference

12 December 2020

Brain-immune connection: immuno-regulatory properties of CNS-resident cells

1 reference

12 December 2020

Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice

1 reference

12 December 2020

The role of CD8(+) T cells in multiple sclerosis and its animal models

1 reference

12 December 2020

Heterogeneity of microglial and perivascular cell populations: insights gained from the facial nucleus paradigm

1 reference

12 December 2020

Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia

1 reference

12 December 2020

Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Turnover of rat brain perivascular cells

1 reference

12 December 2020

Role of autoreactive CD8+ T cells in organ-specific autoimmune diseases: insight from transgenic mouse models

1 reference

12 December 2020

The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis.

1 reference

12 December 2020

Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

1 reference

12 December 2020

Immune regulation by brain cells in the central nervous system: microglia but not astrocytes present myelin basic protein to encephalitogenic T cells under in vivo-mimicking conditions

1 reference

12 December 2020

MRI aspects of the "inflammatory phase" of multiple sclerosis.

1 reference

12 December 2020

Immune function of microglia

1 reference

12 December 2020

Basic principles of immunological surveillance of the normal central nervous system

1 reference

12 December 2020

Bone marrow-derived elements in the central nervous system: an immunohistochemical and ultrastructural survey of rat chimeras

1 reference

12 December 2020

IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

1 reference

12 December 2020

Failed central nervous system regeneration: a downside of immune privilege?

1 reference

12 December 2020

Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts

1 reference

12 December 2020

Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy.

1 reference

12 December 2020

Bacillus Calmette-Guérin sequestered in the brain parenchyma escapes immune recognition

1 reference

12 December 2020

Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells

1 reference

12 December 2020

Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy.

1 reference

12 December 2020

How to drain without lymphatics? Dendritic cells migrate from the cerebrospinal fluid to the B-cell follicles of cervical lymph nodes

1 reference

12 December 2020

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

1 reference

12 December 2020

Immunopathogenesis of multiple sclerosis: MBP and beyond

1 reference

12 December 2020

Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye.

1 reference

12 December 2020

Role of cervical lymph nodes in autoimmune encephalomyelitis in the Lewis rat.

1 reference

12 December 2020

Dissection of an inflammatory process induced by CD8+ T cells

1 reference

12 December 2020

Neuroprotection by encephalomyelitis: rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells.

1 reference

12 December 2020

Astrocytes express elements of the class II endocytic pathway and process central nervous system autoantigen for presentation to encephalitogenic T cells

1 reference

12 December 2020

Studies on the problem of corneal homografts

1 reference

12 December 2020

H. polygyrus: B7-independence of the secondary type 2 response

1 reference

12 December 2020

The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system.

1 reference

12 December 2020

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

12 December 2020

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

12 December 2020

IFN-gamma-activated primary murine astrocytes express B7 costimulatory molecules and prime naive antigen-specific T cells

1 reference

12 December 2020

Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice

1 reference

12 December 2020

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma

1 reference

12 December 2020

Immunologically privileged sites

1 reference

12 December 2020

A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

1 reference

12 December 2020

The role of T-cell-mediated mechanisms in virus infections of the nervous system

1 reference

12 December 2020

Naive T lymphocytes traffic to inflamed central nervous system, but require antigen recognition for activation

1 reference

12 December 2020

Differentiated Th1 autoreactive effector cells can induce experimental autoimmune encephalomyelitis in the absence of IL-12 and CD40/CD40L interactions

1 reference

12 December 2020

IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide

1 reference

12 December 2020

Astrocytes and central nervous system endothelial cells do not express B7-1 (CD80) or B7-2 (CD86) immunoreactivity during experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats.

1 reference

12 December 2020

Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells

1 reference

12 December 2020

Autoimmune intervention by CD154 blockade prevents T cell retention and effector function in the target organ

1 reference

12 December 2020

Vasoactive intestinal polypeptide inhibits the expression of the MHC class II antigens on astrocytes

1 reference

12 December 2020

Apoptosis of inflammatory cells in immune control of the nervous system: role of glia

1 reference

12 December 2020

IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

Kinetics of expression of costimulatory molecules and their ligands in murine relapsing experimental autoimmune encephalomyelitis in vivo.

1 reference

12 December 2020

Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new view

1 reference

12 December 2020

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1 reference

12 December 2020

The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis

1 reference

12 December 2020

Targeting of adoptively transferred experimental allergic encephalitis lesion at the sites of wallerian degeneration.

1 reference

12 December 2020

TLR signaling tailors innate immune responses in human microglia and astrocytes

1 reference

12 December 2020

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

12 December 2020

Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis.

1 reference

12 December 2020

Distinct inflammatory stimuli induce different patterns of myelin phagocytosis and degradation in recruited macrophages.

1 reference

12 December 2020

CD95-CD95L: can the brain learn from the immune system?

1 reference

12 December 2020

T cells in the central nervous system: the delicate balance between viral clearance and disease

1 reference

12 December 2020

A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation

1 reference

12 December 2020

Activation of adult human derived microglia by myelin phagocytosis in vitro

1 reference

12 December 2020

Functional activation of myelin-specific T cells by virus-induced molecular mimicry

1 reference

12 December 2020

Migration of Hematogenous Cells Through the Blood-Brain Barrier and the Initiation of CNS Inflammation

1 reference

12 December 2020

Astrocytic factors deactivate antigen presenting cells that invade the central nervous system.

1 reference

12 December 2020

T cell mediated neuroprotection is a physiological response to central nervous system insults

1 reference

12 December 2020

Microglia stimulate naive T-cell differentiation without stimulating T-cell proliferation

1 reference

12 December 2020

Inflammation and atrophy in multiple sclerosis: MRI associations with disease course

1 reference

12 December 2020

Requirement for Θ-Bearing Cells in Lymphocytic Choriomeningitis Virus-induced Central Nervous System Disease

1 reference

12 December 2020

Interactions between hemopoietically derived TNF and central nervous system-resident glial chemokines underlie initiation of autoimmune inflammation in the brain

1 reference

12 December 2020

Multiple sclerosis trial designs for the 21st century: building on recent lessons

1 reference

12 December 2020

Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

1 reference

12 December 2020

Mouse resident microglia: isolation and characterization of immunoregulatory properties with naïve CD4+ and CD8+ T-cells

1 reference

12 December 2020

In vivo detection of myelin proteins in cervical lymph nodes of MS patients using ultrasound-guided fine-needle aspiration cytology

1 reference

12 December 2020

Investigation on the expression of major histocompatibility complex class II and cytokines and detection of HIV-1 DNA within brains of asymptomatic and symptomatic HIV-1-positive patients

1 reference

12 December 2020

The use of magnetic resonance imaging in the diagnosis and long-term management of multiple sclerosis

1 reference

12 December 2020

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

12 December 2020

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

1 reference

12 December 2020

Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation

1 reference

12 December 2020

Microglia induce CD4 T lymphocyte final effector function and death

1 reference

12 December 2020

Ia expression and antigen presentation by glia: strain and cell type-specific differences among rat astrocytes and microglia

1 reference

12 December 2020

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

1 reference

12 December 2020

Presentation of proteolipid protein epitopes and B7-1-dependent activation of encephalitogenic T cells by IFN-gamma-activated SJL/J astrocytes

1 reference

12 December 2020

EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses

1 reference

12 December 2020

Regulation and function of class II major histocompatibility complex, CD40, and B7 expression in macrophages and microglia: Implications in neurological diseases

1 reference

12 December 2020

CD40 engagement stimulates IL-12 p70 production by human microglial cells: basis for Th1 polarization in the CNS

1 reference

12 December 2020

Anti-inflammatory cytokines: expression and action in the brain

1 reference

12 December 2020

Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence.

1 reference

12 December 2020

IL-23: a cytokine that acts on memory T cells

1 reference

12 December 2020

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells

1 reference

12 December 2020

Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system

1 reference

12 December 2020

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

1 reference

12 December 2020

10.1007/S00109-006-0065-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json