(Q36415172)

14 August 2017

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title

The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function (English)

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14 August 2017

Binks W Wattenberg

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14 August 2017

Stuart M Pitson

series ordinal

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14 August 2017

Daniel M Raben

series ordinal

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14 August 2017

language of work or name

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6 March 2006

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Journal of Lipid Research

14 August 2017

published in

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14 August 2017

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14 August 2017

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14 August 2017

page(s)

1128-1139

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Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization

14 August 2017

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Diacylglycerol kinases

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The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases

21 January 2018

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21 January 2018

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Characterization of the Drosophila sphingosine kinases and requirement for Sk2 in normal reproductive function

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CpG island of rat sphingosine kinase-1 gene: tissue-dependent DNA methylation status and multiple alternative first exons

21 January 2018

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Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

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Mouse sphingosine kinase isoforms SPHK1a and SPHK1b differ in enzymatic traits including stability, localization, modification, and oligomerization

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Asp177 in C4 domain of mouse sphingosine kinase 1a is important for the sphingosine recognition

21 January 2018

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An assay for sphingosine kinase activity using biotinylated sphingosine and streptavidin-coated membranes

21 January 2018

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The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

21 January 2018

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Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

21 January 2018

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Escherichia coli diacylglycerol kinase is an evolutionarily optimized membrane enzyme and catalyzes direct phosphoryl transfer.

21 January 2018

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Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase

21 January 2018

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Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

21 January 2018

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Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells: response to cytokines

21 January 2018

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Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

21 January 2018

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Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

21 January 2018

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Role of sphingosine kinase in Ca(2+) signalling by epidermal growth factor receptor

21 January 2018

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Sphingosine kinase: a point of convergence in the action of diverse neutrophil priming agents

21 January 2018

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Activation of sphingosine kinase by the bradykinin B2 receptor and its implication in regulation of the ERK/MAP kinase pathway

21 January 2018

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Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors

21 January 2018

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Role of sphingosine kinase 2 in cell migration toward epidermal growth factor

21 January 2018

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IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses

21 January 2018

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Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

21 January 2018

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Subcellular study of sphingoid base phosphorylation in rat tissues: evidence for multiple sphingosine kinases

21 January 2018

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PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA)

21 January 2018

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Ca2+/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation.

21 January 2018

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Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis

21 January 2018

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Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factor

21 January 2018

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Identification of functional nuclear export sequences in human sphingosine kinase 1

21 January 2018

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21 January 2018

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Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation

21 January 2018

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Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF beta receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells

21 January 2018

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Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells

21 January 2018

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Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling

21 January 2018

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EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration

21 January 2018

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Antisense knockdown of sphingosine kinase 1 in human macrophages inhibits C5a receptor-dependent signal transduction, Ca2+ signals, enzyme release, cytokine production, and chemotaxis

21 January 2018

1 reference

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Dual effects of IGFBP-3 on endothelial cell apoptosis and survival: involvement of the sphingolipid signaling pathways

21 January 2018

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Sphingosine kinase 1 is an intracellular effector of phosphatidic acid

21 January 2018

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The mechanism of membrane targeting of human sphingosine kinase 1.

21 January 2018

1 reference

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Identification of PECAM-1 association with sphingosine kinase 1 and its regulation by agonist-induced phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Delta-catenin/NPRAP (neural plakophilin-related armadillo repeat protein) interacts with and activates sphingosine kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling

21 January 2018

1 reference

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Cloning and characterization of a protein kinase A anchoring protein (AKAP)-related protein that interacts with and regulates sphingosine kinase 1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Aminoacylase 1 is a sphingosine kinase 1-interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Sphingosine kinase 1 (SK1) is recruited to nascent phagosomes in human macrophages: inhibition of SK1 translocation by Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase

21 January 2018

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Effect of a membrane-targeted sphingosine kinase 1 on cell proliferation and survival.

21 January 2018

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Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae

21 January 2018

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Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Apical uptake and transepithelial transport of sphingosine monomers through intact human intestinal epithelial cells: physicochemical and molecular modeling studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

21 January 2018

1 reference

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Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets

21 January 2018

1 reference

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Extracellular release of newly synthesized sphingosine-1-phosphate by cerebellar granule cells and astrocytes

21 January 2018

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Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

21 January 2018

1 reference

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Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2

21 January 2018

1 reference

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Sphingosine 1-phosphate signalling and termination at lipid phosphate receptors

21 January 2018

1 reference

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Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis

21 January 2018

1 reference

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Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

21 January 2018

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Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy

21 January 2018

1 reference

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Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Diacylglycerol kinases in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Arachidonoyl-specific diacylglycerol kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

The cysteine-rich domain of human proteins, neuronal chimaerin, protein kinase C and diacylglycerol kinase binds zinc. Evidence for the involvement of a zinc-dependent structure in phorbol ester binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Molecular cloning of a Drosophila diacylglycerol kinase gene that is expressed in the nervous system and muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

The C-terminal part of diacylglycerol kinase alpha lacking zinc fingers serves as a catalytic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Structure-activity relationship of diacylglycerol kinase theta

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Diacylglycerol kinase delta suppresses ER-to-Golgi traffic via its SAM and PH domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Role of diacylglycerol kinase alpha in the attenuation of receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro an

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

AtDGK2, a novel diacylglycerol kinase from Arabidopsis thaliana, phosphorylates 1-stearoyl-2-arachidonoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol and exhibits cold-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Analysis of a novel diacylglycerol kinase from Dictyostelium discoideum: DGKA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Dictyostelium discoideum has a single diacylglycerol kinase gene with similarity to mammalian theta isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Physiological implications of the contrasting modulation of the activities of the epsilon- and zeta-isoforms of diacylglycerol kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Affinity purification and catalytic properties of a soluble, Ca2+-independent, diacylglycerol kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Multiple factors influence the binding of a soluble, Ca2+-independent, diacylglycerol kinase to unilamellar phosphoglyceride vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Membrane translocation of protein kinase Ctheta during T lymphocyte activation requires phospholipase C-gamma-generated diacylglycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Phorbol ester-regulated oligomerization of diacylglycerol kinase delta linked to its phosphorylation and translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Association of diacylglycerol kinase zeta with protein kinase C alpha: spatial regulation of diacylglycerol signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Protein kinase C alpha phosphorylates and negatively regulates diacylglycerol kinase zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-ε

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Src-mediated activation of alpha-diacylglycerol kinase is required for hepatocyte growth factor-induced cell motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Gonadotropin-releasing hormone-induced activation of diacylglycerol kinase-zeta and its association with active c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

Translocation of diacylglycerol kinase α to the nuclear matrix of rat thymocytes and peripheral T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.R600003-JLR200

10.1194/JLR.R600003-JLR200

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference