(Q36369989)

13 August 2017

A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex (English)

1 reference

13 August 2017

J Michael White

1 reference

13 August 2017

C B Williams

1 reference

13 August 2017

D L Engle

series ordinal

1 reference

13 August 2017

G J Kersh

series ordinal

1 reference

13 August 2017

P M Allen

series ordinal

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 May 1999

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

189

1 reference

13 August 2017

1 reference

13 August 2017

1531-1544

1 reference

In vivo antagonism of a T cell response by an endogenously expressed ligand

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

A basis for alloreactivity: MHC helical residues broaden peptide recognition by the TCR.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

T cell positive selection by a high density, low affinity ligand

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Positive and negative selection invoke distinct signaling pathways.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Endogenous altered peptide ligands can affect peripheral T cell responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Kinetic discrimination in T-cell activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Structures of an MHC class II molecule with covalently bound single peptides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Antigen presentation and T cell development in H2-M-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

T-cell-receptor affinity and thymocyte positive selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

T cell receptor antagonist peptides induce positive selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Antagonism of superantigen-stimulated helper T-cell clones and hybridomas by altered peptide ligand

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

A differential-avidity model for T-cell selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Kinetic proofreading in T-cell receptor signal transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Sequence analysis of peptides bound to MHC class II molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Making the T cell receptor go the distance: a topological view of T cell activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

In vivo expression of a TCR antagonist: T cells escape central tolerance but are antagonized in the periphery

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

In thymic selection, peptide diversity gives and takes away

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Mature T cell reactivity altered by peptide agonist that induces positive selection

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Specificity and flexibility in thymic selection

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Positive and negative selection of an antigen receptor on T cells in transgenic mice.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

Evidence for a differential avidity model of T cell selection in the thymus

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Ligand recognition by alpha beta T cell receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

A molecular map of T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

The repertoire of T cells shaped by a single MHC/peptide ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

CD4 regulation of TCR signaling and T cell differentiation following stimulation with peptides of different affinities for the TCR.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

TCR transgenic mice in which usage of transgenic alpha- and beta-chains is highly dependent on the level of selecting ligand.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

A peptide antigen antagonist prevents the differentiation of T cell receptor transgenic thymocytes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193645

T cell tolerance by clonal elimination in the thymus

21 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Identification of a naturally occurring ligand for thymic positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Positive and negative thymocyte selection induced by different concentrations of a single peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

The imprint of intrathymic self-peptides on the mature T cell receptor repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Positive and Negative CD4+ Thymocyte Selection by a Single MHC Class II/Peptide Ligand Affected by Its Expression Level in the Thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

A vector driving the expression of foreign cDNAs in the MHC class II-positive cells of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Crystallization and preliminary x-ray diffraction studies of two new antigen-antibody (lysozyme-Fab) complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.10.1531

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10330432

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10330432

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.189.10.1531

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

10330432

1 reference