(Q36328926)

13 August 2017

title

Facilitating physiologic self-regeneration: a step beyond islet cell replacement (English)

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13 August 2017

David K C Cooper

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13 August 2017

Pleunie P M Rood

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13 August 2017

Rita Bottino

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13 August 2017

A N Balamurugan

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13 August 2017

Yong Fan

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13 August 2017

Massimo Trucco

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13 August 2017

publication date

1 January 2006

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13 August 2017

published in

Pharmaceutical Research

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13 August 2017

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13 August 2017

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13 August 2017

page(s)

227-242

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To be or not to be Asp 57, that is the question

13 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-005-9095-6

Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-005-9095-6

NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-005-9095-6

Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass

21 January 2018

1 reference

12 December 2020

Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound

1 reference

12 December 2020

Compensatory Growth of Pancreatic -Cells in Adult Rats After Short-Term Glucose Infusion

1 reference

12 December 2020

Transplantation of porcine fetal pancreas to diabetic patients

1 reference

12 December 2020

Prior streptozotocin treatment does not inhibit pancreas regeneration after 90% pancreatectomy in rats

1 reference

12 December 2020

Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

1 reference

12 December 2020

Phage integrases for the construction and manipulation of transgenic mammals

1 reference

12 December 2020

Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

1 reference

12 December 2020

Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer

1 reference

12 December 2020

Flexible management of enzymatic digestion improves human islet isolation outcome from sub-optimal donor pancreata

1 reference

12 December 2020

Hepatocyte Growth Factor Gene Therapy for Pancreatic Islets in Diabetes: Reducing the Minimal Islet Transplant Mass Required in a Glucocorticoid-Free Rat Model of Allogeneic Portal Vein Islet Transplantation

1 reference

12 December 2020

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study

1 reference

12 December 2020

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

1 reference

12 December 2020

Isolation of the regulatory regions and genomic organization of the porcine alpha1,3-galactosyltransferase gene

1 reference

12 December 2020

Production of alpha 1,3-galactosyltransferase-deficient pigs

1 reference

12 December 2020

Regeneration of the pancreatic beta cell

1 reference

12 December 2020

Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy

1 reference

12 December 2020

Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol

1 reference

12 December 2020

Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice

1 reference

12 December 2020

Transitional cells in the regenerating pancreas

1 reference

12 December 2020

Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium

1 reference

12 December 2020

Prevention of type 1 diabetes by gene therapy

1 reference

12 December 2020

Anti-CD20 monoclonal antibody treatment in 6 patients with therapy-refractory chronic graft-versus-host disease

1 reference

12 December 2020

Growth factors in the regenerating pancreas of gamma-interferon transgenic mice

1 reference

12 December 2020

Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages

1 reference

12 December 2020

Insulin independence after living-donor distal pancreatectomy and islet allotransplantation

1 reference

12 December 2020

Dendritic Cells Transduced to Express Interleukin-4 Prevent Diabetes in Nonobese Diabetic Mice with Advanced Insulitis

1 reference

12 December 2020

Antisense oligonucleotides down-regulating costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells

1 reference

12 December 2020

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

1 reference

12 December 2020

Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus

1 reference

12 December 2020

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

1 reference

12 December 2020

Pancreas transplantation for patients with type 1 diabetes

1 reference

12 December 2020

Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes.

1 reference

12 December 2020

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

1 reference

12 December 2020

Pancreas and islet transplantation for patients with diabetes

1 reference

12 December 2020

Distinct characteristics and features of allogeneic chimerism in the NOD mouse model of autoimmune diabetes

1 reference

12 December 2020

Pancreatic stem cells

1 reference

12 December 2020

Response of human islets to isolation stress and the effect of antioxidant treatment

1 reference

12 December 2020

Beneficial effects of intensive therapy of diabetes during adolescence: outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT).

1 reference

12 December 2020

The effect of bone marrow and thymus chimerism between non-obese diabetic (NOD) and NOD-E transgenic mice, on the expression and prevention of diabetes

1 reference

12 December 2020

Immunosuppressive agents in organ transplantation: past, present, and future

1 reference

12 December 2020

Blocking of the B7-CD28 pathway increases the capacity of FasL+ (CD95L+) dendritic cells to kill alloactivated T cells

1 reference

12 December 2020

Mortality assessment for pancreas transplants

1 reference

12 December 2020

Activin A and betacellulin: effect on regeneration of pancreatic beta-cells in neonatal streptozotocin-treated rats

1 reference

12 December 2020

Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity

1 reference

12 December 2020

Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy

1 reference

12 December 2020

The pancreatic ductal epithelium serves as a potential pool of progenitor cells

1 reference

12 December 2020

Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia.

1 reference

12 December 2020

Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?

1 reference

12 December 2020

Prevention of type I diabetes in nonobese diabetic mice by allogenic bone marrow transplantation

1 reference

12 December 2020

Islet transplantation as a treatment for diabetes - a work in progress

1 reference

12 December 2020

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

1 reference

12 December 2020

Closing in on type 1 diabetes

1 reference

12 December 2020

Bone marrow-derived stem cells initiate pancreatic regeneration.

1 reference

12 December 2020

Molecular basis of evolutionary loss of the alpha 1,3-galactosyltransferase gene in higher primates

1 reference

12 December 2020

American Society of Gene Therapy meeting. Retroviral vectors: a double-edged sword

1 reference

12 December 2020

Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells

1 reference

12 December 2020

Reversal of diabetes in non-immunosuppressed rhesus macaques by intraportal porcine islet xenografts precedes acute cellular rejection

1 reference

12 December 2020

MHC-linked protection from diabetes dissociated from clonal deletion of T cells

1 reference

12 December 2020

Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice.

1 reference

12 December 2020

A complicated relationship: fulfilling the interactive needs of the T lymphocyte and the dendritic cell

1 reference

12 December 2020

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

12 December 2020

Beta-cell replacement for type I diabetes

1 reference

12 December 2020

Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner

1 reference

12 December 2020

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1 reference

12 December 2020

Automated method for isolation of human pancreatic islets

1 reference

12 December 2020

Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity

1 reference

12 December 2020

Genetically engineered pigs

1 reference

12 December 2020

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

1 reference

12 December 2020

'Green mice' as a source of ubiquitous green cells.

1 reference

12 December 2020

Tolerance through bone marrow transplantation with costimulation blockade

1 reference

12 December 2020

Proliferation and hypertrophy of liver cells surrounding islet grafts in diabetic recipient rats

1 reference

12 December 2020

Dendritic cells as regulators of immune reactivity: implications for transplantation

1 reference

12 December 2020

Islet regeneration needed for overcoming autoimmune destruction - considerations on the pathogenesis of type 1 diabetes

1 reference

12 December 2020

No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo

1 reference

12 December 2020

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

12 December 2020

Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.

1 reference

12 December 2020

Five-year follow-up after clinical islet transplantation

1 reference

12 December 2020

beta-cell neogenesis during prolonged hyperglycemia in rats

1 reference

12 December 2020

In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells

1 reference

12 December 2020

In vivo effect of FK506 on human pancreatic islets

1 reference

12 December 2020

Magnetic resonance-defined periportal steatosis following intraportal islet transplantation: a functional footprint of islet graft survival?

1 reference

12 December 2020

Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting.

1 reference

12 December 2020

Twin-to-twin pancreas transplantation: reversal and reenactment of the pathogenesis of type I diabetes

1 reference

12 December 2020

CD3-specific antibody-induced active tolerance: from bench to bedside

1 reference

12 December 2020

Complete long-term recovery of beta-cell function in autoimmune type 1 diabetes after insulin treatment

1 reference

12 December 2020

Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: radiologic aspects

1 reference

12 December 2020

Harmful delayed effects of exogenous isolation enzymes on isolated human islets: relevance to clinical transplantation

1 reference

12 December 2020

Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trial

1 reference

12 December 2020

Gal alpha 1,3Gal expression on porcine pancreatic islets, testis, spleen, and thymus.

1 reference

12 December 2020

Single-donor, marginal-dose islet transplantation in patients with type 1 diabetes

1 reference

12 December 2020

Pancreatic islet-specific expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene-deficient mice

1 reference

12 December 2020

Efficient gene delivery to human and rodent islets with double-stranded (ds) AAV-based vectors

1 reference

12 December 2020

Dendritic cells and the control of immunity

1 reference

12 December 2020

Successful islet transplantation: continued insulin reserve provides long-term glycemic control

1 reference

12 December 2020

Endocrine pancreas plasticity under physiological and pathological conditions

1 reference

12 December 2020

Beta-cell growth in the neonatal Goto-Kakisaki rat and regeneration after treatment with streptozotocin at birth

1 reference

12 December 2020

Islet/pancreas transplantation: challenges for pediatrics.

1 reference

12 December 2020

Regenerative medicine for diabetes treatment.

1 reference

12 December 2020

A genome-wide search for human type 1 diabetes susceptibility genes

1 reference

12 December 2020

Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets

1 reference

12 December 2020

Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience

1 reference

12 December 2020

Pancreas and islet cell transplantation

1 reference

12 December 2020

Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats.

1 reference

12 December 2020

Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan

1 reference

12 December 2020

Transcriptional inhibition of insulin by FK506 and possible involvement of FK506 binding protein-12 in pancreatic beta-cell.

1 reference

12 December 2020

Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4.

1 reference

12 December 2020

Portal venous pressure changes after sequential clinical islet transplantation

1 reference

12 December 2020

Survival after pancreas transplantation in patients with diabetes and preserved kidney function

1 reference

12 December 2020

Regulation of T cell immunity by dendritic cells

1 reference

12 December 2020

Insulin-dependent diabetes mellitus as an autoimmune disease

1 reference

12 December 2020

Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase

1 reference

12 December 2020

Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

1 reference

12 December 2020

Transdifferentiation versus stem cell hypothesis for the regeneration of islet beta-cells in the pancreas

1 reference

12 December 2020

Risk of developing retinopathy in Diabetes Control and Complications Trial type 1 diabetic patients with good or poor metabolic control

1 reference

12 December 2020

Type 1 diabetes: MHC tailored for diabetes cell therapy

1 reference

12 December 2020

Immunotherapy of NOD mice with bone marrow-derived dendritic cells

1 reference

12 December 2020

Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation

1 reference

12 December 2020

Prevention of diabetes for up to 13 years by autoislet transplantation after pancreatectomy for chronic pancreatitis

1 reference

12 December 2020

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

1 reference

12 December 2020

Serum lipoproteins in the diabetes control and complications trial/epidemiology of diabetes intervention and complications cohort: associations with gender and glycemia

1 reference

12 December 2020

In Vivo Cell Transformation: Neogenesis of Beta Cells from Pancreatic Ductal Cells

1 reference

12 December 2020

10.1007/S11095-005-9095-6

Identifiers

DOI

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13 August 2017

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