(Q36240118)

13 August 2017

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title

The future of asthma therapy: integrating clinical and experimental studies (English)

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13 August 2017

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David B Corry

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13 August 2017

Farrah Kheradmand

series ordinal

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13 August 2017

publication date

1 January 2005

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13 August 2017

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13 August 2017

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13 August 2017

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13 August 2017

page(s)

35-52

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Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

13 August 2017

cites work

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12 December 2020

Identification of A3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice

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12 December 2020

Allergen vaccination with a liposome-encapsulated extract of Dermatophagoides pteronyssinus: a randomized, double-blind, placebo-controlled trial in asthmatic patients

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12 December 2020

Inhibitory effects of an anti-IgE antibody E25 on allergen-induced early asthmatic response

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12 December 2020

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

1 reference

12 December 2020

Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity

1 reference

12 December 2020

Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

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12 December 2020

The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjects

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12 December 2020

IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses.

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12 December 2020

Absence of relationship between tuberculin reactivity and atopy in BCG vaccinated young adults

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12 December 2020

Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response

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12 December 2020

Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice

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12 December 2020

A controlled trial of immunotherapy for asthma in allergic children

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12 December 2020

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

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12 December 2020

IL-4 is required to generate and sustain in vivo IgE responses

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12 December 2020

The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness

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12 December 2020

Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in primates

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12 December 2020

Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells

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12 December 2020

Airway hyperresponsiveness, late allergic response, and eosinophilia are reversed with mycobacterial antigens in ovalbumin-presensitized mice

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12 December 2020

Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia

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12 December 2020

IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development

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12 December 2020

The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma

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12 December 2020

The effect of delipidated deglycolipidated (DDMV) and heat-killed Mycobacterium vaccae in asthma

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12 December 2020

Plasmapheresis in the treatment of steroid-dependent bronchial asthma

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12 December 2020

Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

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12 December 2020

Rhinitis as an independent risk factor for adult-onset asthma.

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12 December 2020

Raised levels of a new immunoglobulin class (IgND) in asthma

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12 December 2020

The inverse association between tuberculin responses and atopic disorder.

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12 December 2020

Liposome-entrapped D. pteronyssinus vaccination in mild asthma patients: effect of 1-year double-blind, placebo-controlled trial on inflammation, bronchial hyperresponsiveness and immediate and late bronchial responses to the allergen

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12 December 2020

Treatment of allergic asthma with monoclonal anti-IgE antibody. rhuMAb-E25 Study Group.

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12 December 2020

Improvement of clinical and immunopathologic parameters in asthmatic children treated for concomitant chronic rhinosinusitis

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12 December 2020

Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Tokyo Joshi-Idai Asthma Research Group

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12 December 2020

T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6.

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12 December 2020

Efficacy of soluble IL-4 receptor for the treatment of adults with asthma

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12 December 2020

Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice.

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12 December 2020

The role of CTLA-4 in regulating Th2 differentiation

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12 December 2020

F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins

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12 December 2020

Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study.

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12 December 2020

Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway

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12 December 2020

Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma

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12 December 2020

Eradication of house dust mite from homes of atopic asthmatic subjects: a double-blind trial

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12 December 2020

Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma

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12 December 2020

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

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12 December 2020

Pharmacokinetics, pharmacodynamics, and safety of inhaled cyclosporin A (ADI628) after single and repeated administration in healthy male and female subjects and asthmatic patients

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12 December 2020

CTLA4Ig inhibits airway eosinophilia and hyperresponsiveness by regulating the development of Th1/Th2 subsets in a murine model of asthma

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12 December 2020

Requirement for IL-13 independently of IL-4 in experimental asthma

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12 December 2020

Endoscopic sinus surgery improves pulmonary function in patients with asthma associated with chronic sinusitis.

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12 December 2020

Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells

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12 December 2020

Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency

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12 December 2020

IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo

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12 December 2020

Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model

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12 December 2020

Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins

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12 December 2020

Murine CTLA4-IgG treatment inhibits airway eosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma

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12 December 2020

Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice

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12 December 2020

B7-CD28/CTLA-4 costimulatory pathways are required for the development of T helper cell 2-mediated allergic airway responses to inhaled antigens

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12 December 2020

Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy.

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12 December 2020

Attenuation of the allergen-induced late asthmatic reaction by cyclosporin A is associated with inhibition of bronchial eosinophils, interleukin-5, granulocyte macrophage colony-stimulating factor, and eotaxin

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12 December 2020

Attenuation of allergic airway inflammation in IL-4 deficient mice

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12 December 2020

IL-4 directs the development of Th2-like helper effectors

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12 December 2020

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

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12 December 2020

Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab).

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12 December 2020

Control of Exposure to Mite Allergen and Allergen-Impermeable Bed Covers for Adults with Asthma

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12 December 2020

Human eosinophil major basic protein causes hyperreactivity of respiratory smooth muscle. Role of the epithelium

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12 December 2020

Effect of suplatast tosilate on airway hyperresponsiveness and inflammation in asthma patients.

1 reference

12 December 2020

The effects of an anti-CD4 monoclonal antibody, keliximab, on peripheral blood CD4+ T-cells in asthma

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12 December 2020

Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice

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12 December 2020

Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

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12 December 2020

To respond or not to respond: T cells in allergic asthma

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12 December 2020

Requirements for allergen-induced airway hyperreactivity in T and B cell-deficient mice

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12 December 2020

The anti-IgE antibody omalizumab improves asthma-related quality of life in patients with allergic asthma

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12 December 2020

A role for the C3a anaphylatoxin receptor in the effector phase of asthma

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12 December 2020

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

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12 December 2020

Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

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12 December 2020

Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma

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12 December 2020

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

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12 December 2020

Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice

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12 December 2020

Cutting edge: the absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy

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12 December 2020

Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway.

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12 December 2020

Cytokine traps: multi-component, high-affinity blockers of cytokine action

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12 December 2020

Targeting cytokines in asthma therapy: round one.

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12 December 2020

Effect of omalizumab on symptoms of seasonal allergic rhinitis: a randomized controlled trial.

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12 December 2020

Therapeutic effect of Bacillus Calmette-Guerin with allergen on human allergic asthmatic patients.

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12 December 2020

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

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12 December 2020

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet

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12 December 2020

Effects of interleukin 5-induced pulmonary eosinophilia on airway reactivity in the guinea pig

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12 December 2020

Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production

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12 December 2020

A multicenter, randomized, double-blind, placebo-controlled trial of high-dose intravenous immunoglobulin for oral corticosteroid-dependent asthma.

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12 December 2020

Therapeutic effects of BCG vaccination in adult asthmatic patients: a randomized, controlled trial

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12 December 2020

Effect of endoscopic sinus surgery on asthmatic patients with chronic rhinosinusitis.

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12 December 2020

A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease

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12 December 2020

Effect of intravenous immunoglobulin on steroid consumption in patients with severe asthma: a double-blind, placebo-controlled, randomized trial.

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12 December 2020

Concomitant chronic sinusitis treatment in children with mild asthma: the effect on bronchial hyperresponsiveness.

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12 December 2020

Omalizumab provides long-term control in patients with moderate-to-severe allergic asthma

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12 December 2020

Effects of an antibody to interleukin-5 in a monkey model of asthma

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12 December 2020

Differential requirement for CD18 in T-helper effector homing

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12 December 2020

Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis

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12 December 2020

Prospective, double-blind, placebo-controlled, multicentre study on the effect of high-dose, intravenous immunoglobulin in children and adolescents with severe bronchial asthma

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12 December 2020

Identifiers

DOI

10.1385/IR:33:1:035

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Dimensions Publication ID

13 August 2017

1019585851

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