(Q36237614)

12 August 2017

The p53 protein is an unusually shaped tetramer that binds directly to DNA. (English)

1 reference

12 August 2017

P N Friedman

1 reference

12 August 2017

X Chen

series ordinal

1 reference

12 August 2017

J Bargonetti

series ordinal

1 reference

12 August 2017

C Prives

series ordinal

1 reference

12 August 2017

language of work or name

English

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publication date

1 April 1993

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

12 August 2017

3319-3323

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Oligomerization of oncoprotein p53.

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Protein folding and intracellular transport: evaluation of conformational changes in nascent exocytotic proteins.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

A potential transcriptional activation element in the p53 protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Wild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Structural aspects of the p53 protein in relation to gene evolution

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Identification of p53 as a sequence-specific DNA-binding protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

A DNA binding domain is contained in the C-terminus of wild type p53 protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

p53 mutations in human cancers

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

A transcriptionally active DNA-binding site for human p53 protein complexes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Mammalian p53 can function as a transcription factor in yeast

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Definition of a consensus binding site for p53

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

The p53 nuclear localisation signal is structurally linked to a p34cdc2 kinase motif

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Presence of a potent transcription activating sequence in the p53 protein

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Tumor suppressor p53: analysis of wild-type and mutant p53 complexes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

Formation of stable p53 homotetramers and multiples of tetramers

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=46291

SV40 T antigen binds specifically to a cellular 53 K protein in vitro

29 June 2018

1 reference

12 December 2020

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

1 reference

12 December 2020

Biochemical and biophysical characterization of the reovirus cell attachment protein sigma 1: evidence that it is a homotrimer

1 reference

12 December 2020

Constitution of the twin polymerase of DNA polymerase III holoenzyme

1 reference

12 December 2020

Wild-type p53 activates transcription in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.90.8.3319

1 reference

release_chqgf5ddqneqfbhmedqenvi64a

12 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/chqgf5ddqneqfbhmedqenvi64a

24 November 2022

mapped directly with Wikidata item

1 reference

12 August 2017

PubMed publication ID

8475074

1 reference