(Q36178225)

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Organotypic liver culture models: meeting current challenges in toxicity testing

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

2 references

19 September 2019

7 October 2019

Organotypic liver culture models: meeting current challenges in toxicity testing (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

biomedical investigative technique

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19 September 2019

human digestive system

1 reference

7 October 2019

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Edward L. LeCluyse

object named as

Edward L LeCluyse

1

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Melvin E. Andersen

object named as

Melvin E Andersen

3

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author name string

Rafal P Witek

2

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Europe PubMed Central

PMC publication ID

12 August 2017

Mark J Powers

4

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Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

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publication date

15 May 2012

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Europe PubMed Central

PMC publication ID

12 August 2017

1 July 2012

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19 September 2019

7 October 2019

Critical Reviews in Toxicology

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Europe PubMed Central

PMC publication ID

12 August 2017

19 September 2019

7 October 2019

42

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

501-548

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Europe PubMed Central

PMC publication ID

12 August 2017

copyright license

Creative Commons Attribution 2.0 Generic

2 references

Europe PubMed Central

19 September 2019

Europe PubMed Central

7 October 2019

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0 references

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Induction of drug metabolizing enzymes: a survey of in vitro methodologies and interpretations used in the pharmaceutical industry--do they comply with FDA recommendations?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Induction of cytochrome P450: assessment in an immortalized human hepatocyte cell line (Fa2N4) using a novel higher throughput cocktail assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Wnt/beta-catenin signaling in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Transcriptional regulation of stellate cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Matrix elasticity directs stem cell lineage specification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cell-based models to study hepatic drug metabolism and enzyme induction in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The isolated perfused rat liver: standardization of a time-honoured model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Bile acid interactions with cholangiocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Heterogeneity of the intrahepatic biliary epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cholangiocyte anion exchange and biliary bicarbonate excretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

CYP induction-mediated drug interactions: in vitro assessment and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

THE ESTIMATION OF HEPATIC BLOOD FLOW IN MAN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Stem cells and their niches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cholangiocyte biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Capturing complex 3D tissue physiology in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Progenitor cells in liver regeneration: molecular responses controlling their activation and expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Characterization of cytochrome P450 expression in murine embryonic stem cell-derived hepatic tissue system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The immunophysiology of biliary epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The challenges of abundance: epithelial junctions and small GTPase signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

TWEAK induces liver progenitor cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Patterned cell culture inside microfluidic devices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Dose-dependent transitions in mechanisms of toxicity: case studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Dose-dependent transitions in mechanisms of toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Lhx2-/- mice develop liver fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Senescence and immortalization: role of telomeres and telomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Convergence of Wnt, beta-catenin, and cadherin pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatic stellate cells: unique characteristics in cell biology and phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Drug uptake systems in liver and kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Discriminating two classes of toxicants through expression analysis of HepG2 cells with DNA arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Heparin-protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Implementation of the 3Rs (refinement, reduction, and replacement): validation and regulatory acceptance considerations for alternative toxicological test methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Functional heterogeneity of cholangiocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Inducible differentiation and morphogenesis of bipotential liver cell lines from wild-type mouse embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The role of cholangiocytes in the development of chronic inflammatory liver disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Alteration of drug biotransformation and elimination during infection and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Review of a flat membrane bioreactor as a bioartificial liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Mechanisms of hepatotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cooperation of liver cells in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The use of genomics technology to investigate gene expression changes in cultured human liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Mediators of inflammation and acute phase response in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatic response to sepsis: interaction between coagulation and inflammatory processes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Prooxidant and antioxidant functions of nitric oxide in liver toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatic stem cells: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Regulation of cytochrome p450 by inflammatory mediators: why and how?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatic polyploidy and liver growth control.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Multiple hepatic adenomas caused by long-term administration of androgenic steroids for aplastic anemia in association with familial adenomatous polyposis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Adhesion of lymphocytes to hepatic endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The structural and mechanical complexity of cell-growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Glutathione depletion is associated with decreased Bcl-2 expression and increased apoptosis in cholangiocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Zonation of cytochrome P450 expression, drug metabolism and toxicity in liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Zonation of parenchymal and nonparenchymal metabolism in liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatic stem cells in liver regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cultured rat hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Gene regulation in rodent hepatocytes during development, differentiation and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cell adhesion molecules in liver function and pattern formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: reciprocal expression of C/EBP alpha and immediate-early growth response transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Characterization and functional studies on rat liver fat-storing cell line and freshly isolated hepatocyte coculture system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The extracellular matrix in hepatic regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Signal transduction by cell adhesion receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinoneimine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Connective tissue biomatrix: its isolation and utilization for long-term cultures of normal rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The hepatic extracellular matrix. I. Electron immunohistochemical studies in normal rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

A domain-specific marker for the hepatocyte plasma membrane: localization of leucine aminopeptidase to the bile canalicular domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Mechanisms of bile formation, hepatic uptake, and biliary excretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cell surface polarity in epithelia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Identification of rat hepatocyte plasma membrane proteins using monoclonal antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Adhesive interactions and the metabolic activity of hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatotoxic effects of the anabolic/androgenic steroids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Current concepts on hepatic transport of drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Conditional enhancement of liver-specific gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The role of extracellular matrix in normal liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Physiologic significance and regulation of hepatocellular heterogeneity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Demonstration by in situ hybridization of the zonal modulation of rat liver cytochrome P-450b and P-450e gene expression after phenobarbital

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Liver pathology in diabetes mellitus and morbid obesity. Clinical, pathological, and biochemical considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Structural and regulatory analysis of the male-specific rat liver cytochrome P-450 g: repression by continuous growth hormone administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Stem cell biology, hormone/matrix synergies and liver differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Evidence from dwarf rats that growth hormone may not regulate the sexual differentiation of liver cytochrome P450 enzymes and steroid 5 alpha-reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Transcriptional regulation of liver-specific gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Cocaine hepatotoxicity: influence of hepatic enzyme inducing and inhibiting agents on the site of necrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Hepatic tissue engineering. Development of critical technologies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Metabolic zonation of the liver: regulation and implications for liver function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Transcription factors and liver-specific genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

A murine tumor producing a matrix of basement membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Perifused monolayer cultures of rat hepatocytes as an improved in vitro system for studies on ureogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Fetal phenotypic expression by adult rat hepatocytes on collagen gel/nylon meshes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

The role of growth hormone, dexamethasone and triiodothyronine in the regulation of glutamine synthetase in primary cultures of rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

Primary culture of parenchymal liver cells on collagen membranes. Morphological and biochemical observations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

1 October 2017

In vitro metabolism of di(2-ethylhexyl) phthalate (DEHP) by various tissues and cytochrome P450s of human and rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Paracrine signals from mesenchymal cell populations govern the expansion and differentiation of human hepatic stem cells to adult liver fates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Engineering analysis and development of the spheroid reservoir bioartificial liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

A microfluidic hepatic coculture platform for cell-based drug metabolism studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Hepatic wound repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

ECVAM's ongoing activities in the area of acute oral toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Volume flow and wall shear stress quantification in the human conjunctival capillaries and post-capillary venules in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Gradients in the liver's extracellular matrix chemistry from periportal to pericentral zones: influence on human hepatic progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Constitutive androstane receptor-vitamin D receptor crosstalk: consequence on CYP24 gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Growth and differentiation of colony-forming human hepatocytes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Formation of steady-state oxygen gradients in vitro: application to liver zonation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Functional behavior of primary rat liver cells in a three-dimensional perfused microarray bioreactor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Adhesion-guided in vitro morphogenesis in pure and mixed cell cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Sex-dependent metabolism of xenobiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Sinusoidal endothelial cells as a target for acetaminophen toxicity. Direct action versus requirement for hepatocyte activation in different mouse strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Gap junctions and growth control in liver regeneration and in isolated rat hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Sulfotransferase gene expression in primary cultures of rat hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Reestablishment of cell polarity of rat hepatocytes in primary culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Rat serum carboxylesterase. Cloning, expression, regulation, and evidence of secretion from liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Xenobiotic-enhanced expression of cytochrome P450 2E1 and 2B1/2B2 in primary cultured rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Complete regression of hepatocellular adenoma after withdrawal of oral contraceptives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Demonstration of glucose 6-phosphatase activity in the oval cells of rat liver and the significance of the oval cells in azo dye carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Long-term effects of physiological oxygen concentrations on glycolysis and gluconeogenesis in hepatocyte cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Mechanism of hepatotoxicity to periportal regions of the liver lobule due to allyl alcohol: role of oxygen and lipid peroxidation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Long-term maintenance of hepatocyte functional activity in co-culture: requirements for sinusoidal endothelial cells and dexamethasone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Cultivation of adult rat hepatocytes on 3T3 cells: expression of various liver differentiated functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Efficient DNA-mediated gene transfer into primary cultures of adult rat hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Spheroidal aggregate culture of rat liver cells: histotypic reorganization, biomatrix deposition, and maintenance of functional activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Long-term culture of rat liver cell spheroids in hormonally defined media

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Transcriptional regulation of the albumin gene in cultured rat hepatocytes. Role of basement-membrane matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Drug metabolizing enzymes in rat hepatocytes co-cultured with cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Heterogeneity of rat liver parenchyma in cholesterol 7 alpha-hydroxylase and bile acid synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Mechanisms controlling growth of hepatocytes in primary culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Hepatocellular phenotype in vitro is influenced by biophysical features of the collagenous substratum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Co-cultures of hepatocytes with epithelial-like cell lines: expression of drug-biotransformation activities by hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Drug metabolizing enzyme activities in rat liver epithelial cell lines, hepatocytes and bile duct cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

DNA binding, adduct characterisation and metabolic activation of aflatoxin B1 catalysed by isolated rat liver parenchymal, Kupffer and endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Involvement of nonparenchymal cells in oxygen-dependent hepatic injury by allyl alcohol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

In vivo formation of aflatoxin B1-DNA adducts in parenchymal and non-parenchymal cells of rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Dependency of the in vitro stabilization of differentiated functions in liver parenchymal cells on the type of cell line used for co-culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Long-term culture of adult rat hepatocyte spheroids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

2 July 2018

A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Tissue models: a living system on a chip.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Microfluidic cell culture chip with multiplexed medium delivery and efficient cell/scaffold loading mechanisms for high-throughput perfusion 3-dimensional cell culture-based assays.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Long-term culture of functional hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Enhanced sensitivity of perifused primary rat hepatocytes to mitogens and growth modulation by carcinogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Virtual tissues in toxicology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Abacavir and didanosine induce the interaction between human leukocytes and endothelial cells through Mac-1 upregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Alkoxyresorufin O-dealkylase assay using a rat hepatocyte spheroid microarray.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Comparative analysis of gene expression in rat liver tissue and monolayer- and spheroid-cultured hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Overcoming barriers to validation of non-animal partial replacement methods/Integrated Testing Strategies: the report of an EPAA-ECVAM workshop.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Engineering liver tissue spheroids with inverted colloidal crystal scaffolds.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Interspecies difference in liver-specific functions and biotransformation of testosterone of primary rat, porcine and human hepatocyte in an organotypical sandwich culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Nuclear magnetic resonance metabolomic footprinting of human hepatic stem cells and hepatoblasts cultured in hyaluronan-matrix hydrogels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Efficient differentiation of functional hepatocytes from human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Microscale culture of human liver cells for drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Hepatocyte transplantation and drug-induced perturbations in liver cell compartments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Wnt/beta-catenin signaling mediates oval cell response in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Dynamics of the self-assembly of complex cellular aggregates on micromolded nonadhesive hydrogels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Hepatic differentiation potential of commercially available human mesenchymal stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Rat liver sinusoidal endothelial cells survive without exogenous VEGF in 3D perfused co-cultures with hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Human hepatoblast phenotype maintained by hyaluronan hydrogels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Role of Kupffer cells in the pathogenesis of liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Suppression of hepatocyte CYP1A2 expression by Kupffer cells via AhR pathway: the central role of proinflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Rat liver endothelial cells isolated by anti-CD31 immunomagnetic separation lack fenestrae and sieve plates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

The sources of parenchymal regeneration after chronic hepatocellular liver injury in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Crucial roles of mesodermal cell lineages in a murine embryonic stem cell-derived in vitro liver organogenesis system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Long-term monitoring of bacteria undergoing programmed population control in a microchemostat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Primary hepatocyte apoptosis is unlikely to relate to caspase-3 activity under sustained endogenous oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Ultrastructural zonal heterogeneity of hepatocytes and mitochondria within the hepatic acinus during liver regeneration after partial hepatectomy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Ethanol binging exacerbates sinusoidal endothelial and parenchymal injury elicited by acetaminophen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

In vitro hepatic differentiation of human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Evaluation of fresh and cryopreserved hepatocytes as in vitro drug metabolism tools for the prediction of metabolic clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Rat liver sinusoidal endothelial cell phenotype is maintained by paracrine and autocrine regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Modeling mass transfer in hepatocyte spheroids via cell viability, spheroid size, and hepatocellular functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Early hepatic microvascular injury in response to acetaminophen toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Liver tissue engineering within alginate scaffolds: effects of cell-seeding density on hepatocyte viability, morphology, and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Time course of cytochromes P450 decline during rat hepatocyte isolation and culture: effect of L-NAME.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Evaluation of the effect of culture configuration on morphology, survival time, antioxidant status and metabolic capacities of cultured rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Shear stress-induced nitric oxide release triggers the liver regeneration cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio- and stereoselective products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Hepatocyte spheroids: prolonged hepatocyte viability for in vitro modeling of nongenotoxic carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Hepatotoxicity of germander in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Intercellular communication in primary cultures of putative preneoplastic and 'normal' hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Inhibition of rat liver gap junction intercellular communication by tumor-promoting agents in vivo. Association with aberrant localization of connexin proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Regulation of hepatic genes and liver transcription factors in rat hepatocytes by extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Lobular and cellular patterns of early hepatic glycogen deposition in the rat as observed by light and electron microscopic radioautography after injection of 3H-galactose.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

Effects of extracellular matrix on hepatocyte growth and gene expression: implications for hepatic regeneration and the repair of liver injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423873

23 September 2018

LONG-TERM CULTURES OF NORMAL RAT HEPATOCYTES ON LIVER BIOMATRIX

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.682115

21 January 2018

Sequential Exposure to Cytokines Reflecting Embryogenesis: The Key for in vitro Differentiation of Adult Bone Marrow Stem Cells into Functional Hepatocyte-like Cells

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.682115

21 January 2018

Maintenance and induction in co-cultured rat hepatocytes of components of the cytochrome P450-mediated mono-oxygenase

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.682115

21 January 2018

Influence of the isolation method on the stability of differentiated phenotype in cultured rat hepatocytes

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.682115

21 January 2018

A Microassay for Measuring Cytochrome P450IA1 and Cytochrome P450IIB1 Activities in Intact Human and Rat Hepatocytes Cultured on 96-Well Plates

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.682115

21 January 2018

An update on metabolism studies using human hepatocytes in primary culture

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.682115

21 January 2018

Primary cultures of rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of rat hepatocyte plasma membrane domains by monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Types I and IV procollagen gene expression in cultured rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocytes may produce laminin in fibrotic liver and in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetaminophen hepatotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factors in the extracellular matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholangiocyte biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell shape, cell-cell contact, cell-extracellular matrix contact and cell polarity are all required for the maximum induction of CYP2B1 and CYP2B2 gene expression by phenobarbital in adult rat cultured hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression in human hepatocytes in suspension after isolation is similar to the liver of origin, is not affected by hepatocyte cold storage and cryopreservation, but is strongly changed after hepatocyte plating

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive detection of growth stimulating tumour promoters in perifused primary rat hepatocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphologic identification by electron microscopy of "oval" cells in experimental hepatic degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hepatic extracellular matrix. I. Components and distribution in normal liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver regeneration in acute severe liver impairment: a clinicopathological correlation study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species differences in 5 alpha-androstane-3 beta,17 beta-diol hydroxylation by rat, monkey, and human prostate microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perfusion of 3D encapsulated hepatocytes-A synergistic effect enhancing long-term functionality in bioreactors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolving concepts in liver tissue modeling and implications for in vitro toxicology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of thyroid and glucocorticoid hormones on the level of messenger ribonucleic acid for iodothyronine type I 5'-deiodinase in rat primary hepatocyte cultures grown as spheroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A perifusion system for cultured hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of cell aggregation for expression of liver functions and regeneration demonstrated with primary cultured hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Glucagon-Insulin Antagonism and Glucagon-Dexamethasone Synergism in the Induction of Phosphoenolpyruvate Carboxykinase in Cultured Rat Hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitheliomesenchymal interaction in pancreatic morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perifusion of co-cultured hepatocytes: optimization of studies on drug metabolism and cytotoxicity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of extracellular matrix components on the growth and differentiation of cultured rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling inflammation-drug interactions in vitro: a rat Kupffer cell-hepatocyte coculture system

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular matrix gradients in the space of Disse: relevance to liver biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continued high albumin production by multicellular spheroids of adult rat hepatocytes formed in the presence of liver-derived proteoglycans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of collagen gel configuration on the cytoskeleton in cultured rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of drug metabolism, drug-drug interactions, and in vitro hepatotoxicity with cryopreserved human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of p53 gene in 184 unifocal hepatocellular carcinomas: association with tumor growth and invasiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and culture of primary human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alcohol-induced sinusoidal endothelial cell dysfunction in the mouse is associated with exacerbated liver apoptosis and can be reversed by caspase inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A protein associated with the mouse and rat hepatocyte junctional complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A microfabricated array bioreactor for perfused 3D liver culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of hepatic cytochrome P-450 isoforms and PPAR-gamma: their role in hepatic injury and proinflammatory responses in a double-hit model of hemorrhage and sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of hydrocortisone on deposition of types I and IV collagen in primary culture of rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced and oxidized glutathione contents in adult rat hepatocytes under various culture conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of the Integrated Discrete Multiple Organ Co-culture (IdMOC) system for the evaluation of multiple organ toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zonal distribution of transcripts of four hepatic transcription factors in the mature rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-Term Co-Cultures of Adult Human Hepatocytes with Rat Liver Epithelial Cells: Modulation of Albumin Secretion and Accumulation of Extracellular Material

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the maintenance of cytochromes P-450 and b5, monooxygenases and cytochrome reductases in primary cultures of rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-substratum adhesion strength as a determinant of hepatocyte aggregate morphology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Luciferin IPA-based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of liver spheroids as an in vitro model for studying induction of the stress response as a marker of chemical toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Culture matrix configuration and composition in the maintenance of hepatocyte polarity and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of xenobiotic-inducible cytochrome P450 gene expression by dexamethasone in primary rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional tissue models for drug discovery and toxicology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A morphological study of differentiated hepatocytesin vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional culture of hepatocytes in a continuously flowing medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic progenitor cells in hepatocellular adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simplified method for the culturing of primary adult rat and human hepatocytes as multicellular spheroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

7-ethoxycoumarin deethylase activity as a convenient measure of liver drug metabolizing enzymes: Regulation in cultured rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissection of the intracellular pathways in hepatocytes suggests a role for Jun kinase and IFN regulatory factor-1 in Con A-induced liver failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct cell-to-cell contact between Kupffer cells and hepatocytes augments endotoxin-induced hepatic injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal regulation of prothrombin secretion and tyrosine aminotransferase induction in hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of freezing, thawing, and storing human liver microsomes on cytochrome P450 activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microcirculatory units in the mammalian liver. Their arterial and portal components

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zonation of acetaminophen metabolism and cytochrome P450 2E1-mediated toxicity studied in isolated periportal and perivenous hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and regulatory analysis of a cytochrome P450 gene (CYP2C12) expressed predominantly in female rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stem cell niche of human livers: symmetry between development and regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A morphometric study of the variations in subcellular structures of rat hepatocytes during 24 hours

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Encapsulated multicellular spheroids of rat hepatocytes produce albumin and urea in a spouted bed circulating culture system

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional control in the production of liver-specific mRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione dependent detoxication in adult rat hepatocytes under various culture conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-alcoholic fatty liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a novel monoclonal antibody, SE-1, which specifically reacts with rat hepatic sinusoidal endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deep intralobular extension of human hepatic 'progenitor cells' correlates with parenchymal inflammation in chronic viral hepatitis: can 'progenitor cells' migrate?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and phase II xenobiotic biotransformation in cultures and co-cultures of adult rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Switching from differentiation to growth in hepatocytes: control by extracellular matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dietary lipid and phenobarbitone on the distribution and concentration of cytochrome P-450 in the liver studied by quantitative cytochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of chloroform and related trihalomethanes to free radical intermediates in isolated hepatocytes and in the rat in vivo as detected by the ESR-spin trapping technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of fetal and neonatal rat hepatocyte functional activity by glucocorticoids in co-culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/22582993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3109/10408444.2012.682115

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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