(Q35922019)

11 August 2017

Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II. (English)

1 reference

11 August 2017

1 reference

11 August 2017

Roger D Kornberg

1 reference

11 August 2017

0 references

Robert Landick

1 reference

11 August 2017

Matthew H Larson

1 reference

11 August 2017

Jing Zhou

series ordinal

1 reference

11 August 2017

Murali Palangat

series ordinal

1 reference

11 August 2017

language of work or name

English

0 references

publication date

9 April 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

1 reference

11 August 2017

109

1 reference

11 August 2017

1 reference

11 August 2017

6555-6560

1 reference

Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Dissection of Pol II trigger loop function and Pol II activity-dependent control of start site selection in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Stepwise mechanism for transcription fidelity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Forks, pincers, and triggers: the tools for nucleotide incorporation and translocation in multi-subunit RNA polymerases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

RNA polymerase II flexibility during translocation from normal mode analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

In vivo dynamics of RNA polymerase II transcription.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Structural basis for substrate loading in bacterial RNA polymerase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Direct versus limited-step reconstitution reveals key features of an RNA hairpin-stabilized paused transcription complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Mutations in the Saccharomyces cerevisiae RPB1 gene conferring hypersensitivity to 6-azauracil

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Direct observation of base-pair stepping by RNA polymerase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Structural basis of transcription inhibition by antibiotic streptolydigin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Backtracking by single RNA polymerase molecules observed at near-base-pair resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

A model for the mechanism of polymerase translocation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Identification of a decay in transcription potential that results in elongation factor dependence of RNA polymerase II.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Applied force reveals mechanistic and energetic details of transcription termination

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Transcriptional fidelity and proofreading by RNA polymerase II.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Connections between translation, transcription and replication error-rates

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking.

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200939109

Role of the RNA polymerase trigger loop in catalysis and pausing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200939109

Dynamic error correction and regulation of downstream bubble opening by human RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200939109

NTP-driven translocation by human RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200939109

Transcription factors IIF and IIS and nucleoside triphosphate substrates as dynamic probes of the human RNA polymerase II mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200939109

Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200939109

Rapid kinetic analysis of transcription elongation by Escherichia coli RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200939109

Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340090

A Ratchet Mechanism of Transcription Elongation and Its Control

24 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1200939109

Multiple RNA polymerase conformations and GreA: control of the fidelity of transcription

21 January 2018

1 reference

12 December 2020

Sequence-dependent kinetic model for transcription elongation by RNA polymerase

1 reference

12 December 2020

Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS

1 reference

12 December 2020

Mechanochemical kinetics of transcription elongation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1200939109

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

22493230

1 reference