(Q35815320)

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Cellular senescence and organismal aging

scientific article published on 12 April 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

10 August 2017

2 references

20 August 2019

10 July 2020

Cellular senescence and organismal aging (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

physiological phenomenon

1 reference

20 August 2019

cellular senescence

1 reference

10 July 2020

2

object named as

John M Sedivy

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

author name string

Jessie C Jeyapalan

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

publication date

12 April 2008

3 references

Europe PubMed Central

PMC publication ID

10 August 2017

20 August 2019

10 July 2020

Mechanisms of Ageing and Development

3 references

Europe PubMed Central

PMC publication ID

10 August 2017

20 August 2019

10 July 2020

129

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

7-8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

467-474

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Role of telomeres in vascular senescence

1 reference

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Studying telomeres in a longitudinal population based study.

1 reference

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Aging, graying and loss of melanocyte stem cells.

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Telomere length, stem cells and aging

1 reference

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Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A.

1 reference

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Cellular senescence: when bad things happen to good cells

1 reference

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11 July 2018

Cellular senescence in cancer and aging

1 reference

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From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing.

1 reference

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Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells

1 reference

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Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay

1 reference

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Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin-dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies

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Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging

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Concise review: Telomere biology in normal and leukemic hematopoietic stem cells

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Adult-onset pulmonary fibrosis caused by mutations in telomerase

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Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases.

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Short telomeres limit tumor progression in vivo by inducing senescence

1 reference

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Flow cytometry and FISH to measure the average length of telomeres (flow FISH).

1 reference

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Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence

1 reference

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Telomerase mutations in families with idiopathic pulmonary fibrosis

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High-throughput telomere length quantification by FISH and its application to human population studies

1 reference

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

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WRN at telomeres: implications for aging and cancer

1 reference

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Telomere dysfunction as a cause of genomic instability in Werner syndrome

1 reference

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

1 reference

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Restoration of p53 function leads to tumour regression in vivo

1 reference

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Molecular dissection of formation of senescence-associated heterochromatin foci

1 reference

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Telomerase induction in T cells: a cure for aging and disease?

1 reference

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Loss of linker histone H1 in cellular senescence

1 reference

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No association between socio-economic status and white blood cell telomere length.

1 reference

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Accumulation of senescent cells in mitotic tissue of aging primates

1 reference

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Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts

1 reference

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Stress, social rank and leukocyte telomere length

1 reference

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Short telomeres: cause or consequence of aging?

1 reference

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A life course perspective on telomere length and social inequalities in aging

1 reference

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The regulation of INK4/ARF in cancer and aging

1 reference

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Human telomere biology: pitfalls of moving from the laboratory to epidemiology

1 reference

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Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

1 reference

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p16INK4a induces an age-dependent decline in islet regenerative potential

1 reference

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Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

1 reference

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Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence

1 reference

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Senescence-associated beta-galactosidase is lysosomal beta-galactosidase

1 reference

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11 July 2018

Increased p53 activity does not accelerate telomere-driven ageing

1 reference

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p63: a new link between senescence and aging

1 reference

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Simultaneous proteomic profiling of four different growth states of human fibroblasts, using amine-reactive isobaric tagging reagents and tandem mass spectrometry

1 reference

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Regulation of growth arrest in senescence: telomere damage is not the end of the story

1 reference

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Identification of differentially expressed proteins in senescent human embryonic fibroblasts

1 reference

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SA beta Gal staining: biomarker or delusion

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The limitations and validities of senescence associated-beta-galactosidase activity as an aging marker for human foreskin fibroblast Hs68 cells

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Obesity, cigarette smoking, and telomere length in women

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p63 deficiency activates a program of cellular senescence and leads to accelerated aging

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

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Tumour biology: senescence in premalignant tumours

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Effects of telomerase and telomere length on epidermal stem cell behavior

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11 July 2018

Telomeres as biomarkers for ageing and age-related diseases.

1 reference

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Skin aging: a role for telomerase and telomere dynamics?

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Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia

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Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers.

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Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

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The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo.

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Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

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Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

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11 July 2018

Accelerated telomere shortening in response to life stress

1 reference

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11 July 2018

Senescent fibroblasts resist apoptosis by downregulating caspase-3.

1 reference

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11 July 2018

Ink4a/Arf expression is a biomarker of aging

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Exploration of replicative senescence-associated genes in human dermal fibroblasts by cDNA microarray technology

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Functional links between telomeres and proteins of the DNA-damage response

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Essential role of limiting telomeres in the pathogenesis of Werner syndrome

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11 July 2018

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

1 reference

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Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

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Down-regulation of tissue inhibitor of matrix metalloprotease-1 (TIMP-1) in aged human skin contributes to matrix degradation and impaired cell growth and survival

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A DNA damage checkpoint response in telomere-initiated senescence

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Lentivector-mediated transfer of Bmi-1 and telomerase in muscle satellite cells yields a duchenne myoblast cell line with long-term genotypic and phenotypic stability.

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Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

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Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity

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The serial cultivation of human diploid cell strains

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DNA damage foci at dysfunctional telomeres

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Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

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Tumor cell senescence in cancer treatment

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Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

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Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

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Telomere shortening and cellular senescence in a model of chronic renal allograft rejection

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Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci

1 reference

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Association between telomere length in blood and mortality in people aged 60 years or older

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Cancer and aging: a model for the cancer promoting effects of the aging stroma

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Oxidative stress shortens telomeres

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Historical claims and current interpretations of replicative aging

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Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction

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Molecular mechanisms of skin ageing

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Microarray analysis of E-box binding-related gene expression in young and replicatively senescent human fibroblasts

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Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells

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Immortalisation and transformation revisited

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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Age-associated differences in cardiovascular inflammatory gene induction during endotoxic stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

The influence of INK4 proteins on growth and self-renewal kinetics of hematopoietic progenitor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Interleukin-1alpha is a paracrine inducer of FGF7, a key epithelial growth factor in benign prostatic hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Telomere shortening is an in vivo marker of myocyte replication and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Rethinking chronic allograft nephropathy: the concept of accelerated senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Endogenous beta-galactosidase activity in continuously nonproliferating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Cloning and identification of genes that associate with mammalian replicative senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

The pathway of cell senescence: WI-38 cells arrest in late G1 and are unable to traverse the cell cycle from a true G0 state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Positional cloning of the Werner's syndrome gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Alterations in contact and density-dependent arrest state in senescent WI-38 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Telomere length and replicative aging in human vascular tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Theories of biological aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Telomeres shorten during ageing of human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Genetic diseases of premature aging as models of senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Senescence as a mode of tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

The relationship between in vitro cellular aging and in vivo human age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

Senescent Human Diploid Cells in Culture: Survival, DNA Synthesis and Morphology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

11 July 2018

A negative feedback signaling network underlies oncogene-induced senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

How old are you now?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Induction of transcriptionally active Jun proteins regulates drug-induced senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

p16INK4A is a robust in vivo biomarker of cellular aging in human skin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

The effects of social status on biological aging as measured by white-blood-cell telomere length.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Hutchinson-Gilford progeria syndrome: review of the phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Cellular senescence in aging primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Oncogene-induced senescence as an initial barrier in lymphoma development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Telomere shortening in T cells correlates with Alzheimer's disease status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Telomere shortening in kidneys with age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Microarray analysis of replicative senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Replicative potential and telomere length in human skeletal muscle: implications for satellite cell-mediated gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

24 September 2018

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297662

15 November 2018

Premature senescence of mesothelial cells is associated with non-telomeric DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular senescence in the pathogenesis of benign prostatic hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor genes in aging human kidney and chronic allograft nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of donor age on the in vitro life span of cultured human arterial smooth-muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Can we learn about aging from a study of Werner's syndrome?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro senescence of Syrian hamster mesenchymal cells of fetal to aged adult origin. Inverse relationship between in vivo donor age and in vitro proliferative capacity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of fibroblast stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dyskeratosis congenita

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis resistance of senescent human fibroblasts is correlated with the absence of nuclear IGFBP-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere-end processing the terminal nucleotides of human chromosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere shortening in human coronary artery diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocytes of exceptionally old persons display ultra-short telomeres

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed kinetics of DNA double-strand break processing in normal and pathological aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of chondrocyte senescence in osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histological and ultrastructural features of atherosclerosis in progeria

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is beta-galactosidase staining a marker of senescence in vitro and in vivo?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere attrition of the human abdominal aorta: relationships with age and atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term culture of human adult liver cells: morphological changes related to in vitro senescence and effect of donor's age on growth potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/18502472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MAD.2008.04.001

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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