(Q35567371)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Michelle L McWhorter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Umrao R Monani

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Christine E Beattie

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

language of work or name

English

0 references

publication date

1 September 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

number of pages

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

162

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

919-931

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization.

7 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Macromolecular complexes: SMN--the master assembler

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Co-regulation of survival of motor neuron (SMN) protein and its interactor SIP1 during development and in spinal muscular atrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Control of motor axon guidance in the zebrafish embryo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The exon 2b region of the spinal muscular atrophy protein, SMN, is involved in self-association and SIP1 binding

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Effective targeted gene 'knockdown' in zebrafish

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Zebrafish: bridging the gap between development and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter/enhancer.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

A mouse model for spinal muscular atrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Radiation hybrid mapping of the zebrafish genome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The domain encoded by exon 2 of the survival motor neuron protein mediates nucleic acid binding.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

12 July 2018

Spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The survival motor neuron protein in spinal muscular atrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Correlation between severity and SMN protein level in spinal muscular atrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Promoter analysis in living zebrafish embryos identifies a cis-acting motif required for neuronal expression of GATA-2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The neurobiology of childhood spinal muscular atrophy.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The molecular biology of axon guidance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

A novel nuclear structure containing the survival of motor neurons protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Stages of embryonic development of the zebrafish

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Identification and characterization of a spinal muscular atrophy-determining gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Rohon-beard cells and other large neurons in Xenopus embryos originate during gastrulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The genetic component in child mortality

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Myosin expression and specialization among the earliest muscle fibers of the developing avian limb

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Development of reticulospinal neurons of the zebrafish. I. Time of origin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Segmental homologies among reticulospinal neurons in the hindbrain of the zebrafish larva

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Development of spinal neurons and tracts in the zebrafish embryo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Primary neurons that express the L2/HNK-1 carbohydrate during early development in the zebrafish.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Role of the floor plate in axonal patterning in the zebrafish CNS

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The RNA-binding properties of SMN: deletion analysis of the zebrafish orthologue defines domains conserved in evolution

12 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Motor unit number estimation in infants and children with spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Apoptosis in the developing zebrafish embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Cloning, characterization, and copy number of the murine survival motor neuron gene: homolog of the spinal muscular atrophy-determining gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Survival motor neuron (SMN) protein: role in neurite outgrowth and neuromuscular maturation during neuronal differentiation and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Calmodulin and profilin coregulate axon outgrowth in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Hu neuronal proteins are expressed in proliferating neurogenic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

cDNA isolation, expression, and chromosomal localization of the mouse survival motor neuron gene (Smn).

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Headwaters of the zebrafish -- emergence of a new model vertebrate

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Knockdown of duplicated zebrafish hoxb1 genes reveals distinct roles in hindbrain patterning and a novel mechanism of duplicate gene retention

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1761110

The Relationship between SMN, the Spinal Muscular Atrophy Protein, and Nuclear Coiled Bodies in Differentiated Tissues and Cultured Cells

26 September 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Pathway selection by growth cones of identified motoneurones in live zebra fish embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Neurofilament accumulation at the motor endplate and lack of axonal sprouting in a spinal muscular atrophy mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

The growth cones of identified motoneurons in embryonic zebrafish select appropriate pathways in the absence of specific cellular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Secondary motoneuron axons localize DM-GRASP on their fasciculated segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Filament assembly from profilin-actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

A confocal study of spinal interneurons in living larval zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

The survival motor neuron (SMN) protein: effect of exon loss and mutation on protein localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

An exonic enhancer is required for inclusion of an essential exon in the SMA-determining gene SMN

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Subcellular localization and axonal transport of the survival motor neuron (SMN) protein in the developing rat spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200303168

Development and axonal outgrowth of identified motoneurons in the zebrafish

21 January 2018

1 reference

12 December 2020

Pathfinding by zebrafish motoneurons in the absence of normal pioneer axons

1 reference

12 December 2020

Identification of separate slow and fast muscle precursor cells in vivo, prior to somite formation

1 reference

12 December 2020

Pathfinding by identified zebrafish motoneurons in the absence of muscle pioneers

1 reference

12 December 2020

Mutations in the stumpy gene reveal intermediate targets for zebrafish motor axons

1 reference

12 December 2020

Paralytic zebrafish lacking acetylcholine receptors fail to localize rapsyn clusters to the synapse

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200303168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

12952942

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12952942%20AND%20SRC:MED&resulttype=core&format=json