(Q35222789)

7 August 2017

title

The activity of siRNA in mammalian cells is related to structural target accessibility: a comparison with antisense oligonucleotides (English)

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7 August 2017

author name string

Rosel Kretschmer-Kazemi Far

series ordinal

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7 August 2017

Georg Sczakiel

series ordinal

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7 August 2017

language of work or name

English

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publication date

1 August 2003

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7 August 2017

published in

Nucleic Acids Research

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

4417-4424

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Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant rat P2X3 receptor

7 August 2017

cites work

1 reference

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The effectiveness of double-stranded short inhibitory RNAs (siRNAs) may depend on the method of transfection

13 July 2018

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siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells

13 July 2018

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Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3'-ends of siRNAs

13 July 2018

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The role of target accessibility for antisense inhibition.

13 July 2018

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Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

13 July 2018

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Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

13 July 2018

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13 July 2018

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13 July 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

13 July 2018

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HIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: site selection and inhibition in cell culture

13 July 2018

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RNA accessibility prediction: a theoretical approach is consistent with experimental studies in cell extracts

13 July 2018

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13 July 2018

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Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

13 July 2018

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13 July 2018

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In vitro selection of fast-hybridizing and effective antisense RNAs directed against the human immunodeficiency virus type 1.

13 July 2018

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Arrays of complementary oligonucleotides for analysing the hybridisation behaviour of nucleic acids

13 July 2018

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A computer program for choosing optimal oligonucleotides for filter hybridization, sequencing and in vitro amplification of DNA

13 July 2018

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On finding all suboptimal foldings of an RNA molecule

13 July 2018

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13 July 2018

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Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms

13 July 2018

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Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

13 July 2018

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Theoretical and experimental approaches to design effective antisense oligonucleotides.

26 September 2018

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Comparison of the Suppressive Effects of Antisense Oligonucleotides and siRNAs Directed Against the Same Targets in Mammalian Cells

26 September 2018

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Concepts to automate the theoretical design of effective antisense oligonucleotides

15 November 2018

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12 December 2020

The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript

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12 December 2020

Combinatorial screening and rational optimization for hybridization to folded hepatitis C virus RNA of oligonucleotides with biological antisense activity

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12 December 2020

The association of complementary ribonucleic acids can be strongly increased without lowering Arrhenius activation energies or significantly altering structures

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12 December 2020

Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries

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12 December 2020

ECV304 (endothelial) is really T24 (bladder carcinoma): cell line cross- contamination at source

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKG649

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7 August 2017

1 reference

7 August 2017

1 reference