(Q35047062)

6 August 2017

1 reference

title

Enteric P2X receptors as potential targets for drug treatment of the irritable bowel syndrome (English)

1 reference

6 August 2017

main subject

irritable bowel syndrome

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author name string

James J Galligan

series ordinal

1 reference

6 August 2017

language of work or name

English

0 references

publication date

29 March 2004

1 reference

British Journal of Pharmacology

6 August 2017

published in

1 reference

6 August 2017

volume

141

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6 August 2017

1 reference

6 August 2017

page(s)

1294-1302

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Intrinsic primary afferent neurons and nerve circuits within the intestine

6 August 2017

cites work

1 reference

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Alosetron and irritable bowel syndrome

8 July 2018

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Subunit Arrangement in P2X Receptors

8 July 2018

1 reference

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Crossing the pain barrier: P2 receptors as targets for novel analgesics.

8 July 2018

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Clinical trial guidelines for pharmacological treatment of irritable bowel syndrome

8 July 2018

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Evaluation of drug treatment in irritable bowel syndrome

8 July 2018

1 reference

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P2X2 subunits contribute to fast synaptic excitation in myenteric neurons of the mouse small intestine

8 July 2018

1 reference

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Alosetron in irritable bowel syndrome: strategies for its use in a common gastrointestinal disorder

8 July 2018

1 reference

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P2X3 receptors and peripheral pain mechanisms

8 July 2018

1 reference

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Peristalsis is impaired in the small intestine of mice lacking the P2X3 subunit

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Incidence of colonic ischemia, hospitalized complications of constipation, and bowel surgery in relation to use of alosetron hydrochloride

8 July 2018

1 reference

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Tegaserod: a review of its use in the management of irritable bowel syndrome with constipation in women

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Neuroimmune and epithelial interactions in intestinal inflammation.

8 July 2018

1 reference

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The pharmacology of gastrointestinal nociceptive pathways.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

AGA technical review on irritable bowel syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

A randomized, double-blind, placebo-controlled trial of tegaserod in female patients suffering from irritable bowel syndrome with constipation

8 July 2018

1 reference

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Molecular physiology of P2X receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Irritable bowel syndrome neuropharmacology. A review of approved and investigational compounds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Evolving pathophysiologic models of functional gastrointestinal disorders

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Review article: the complexity of drug development for irritable bowel syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

TEA- and apamin-resistant K(Ca) channels in guinea-pig myenteric neurons: slow AHP channels

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

P2X(7) receptors in the enteric nervous system of guinea-pig small intestine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

P2X receptors and nociception

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Gastrointestinal afferents as targets of novel drugs for the treatment of functional bowel disorders and visceral pain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

8 July 2018

Synaptic P2X receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Receptors and transmission in the brain-gut axis: potential for novel therapies. I. Receptors on visceral afferents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Molecular physiology of P2X receptors and ATP signalling at synapses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Excitatory synaptic inputs on myenteric Dogiel type II neurones of the pig ileum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Neurotransmitters in neuronal reflexes regulating intestinal secretion.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

IL-1beta and IL-10 have dual effects on enteric glial cell proliferation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Nucleotide receptors: an emerging family of regulatory molecules in blood cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Consequences of intestinal inflammation on the enteric nervous system: neuronal activation induced by inflammatory mediators.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Classes of enteric nerve cells in the guinea-pig small intestine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Neuronal P2X receptors: localisation and functional properties.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Sympathetic input into the enteric nervous system.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Vagal input to the enteric nervous system.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

The neurobiology of stress and gastrointestinal disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Multiple mechanisms of fast excitatory synaptic transmission in the enteric nervous system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Pharmacology of cloned P2X receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Responses of afferent neurons to the contents of the digestive tract, and their relation to endocrine and immune responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

P2X purinoceptor-induced sensitization of ferret vagal mechanoreceptors in oesophageal inflammation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Purinergic and cholinergic neuro-neuronal transmission underlying reflexes activated by mucosal stimulation in the isolated guinea-pig ileum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised rat.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

IL-1beta and IL-6 excite neurons and suppress nicotinic and noradrenergic neurotransmission in guinea pig enteric nervous system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

The enteric nervous system and regulation of intestinal motility.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Intrinsic primary afferent neurons of the intestine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Purinergic fast excitatory postsynaptic potentials in myenteric neurons of guinea pig: distribution and pharmacology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

P2x-purinoceptors of myenteric neurones from the guinea-pig ileum and their unusual pharmacological properties

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

P2X purinoceptors in cultured myenteric neurons of guinea-pig small intestine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Intracellular recording from the myenteric plexus of the guinea-pig ileum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Projections of submucosal neurons to the myenteric plexus of the guinea pig intestine: in vitro tracing of microcircuits by retrograde and anterograde transport

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

The slow calcium-dependent potassium current in a myenteric neurone of the guinea-pig ileum.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Electrical and synaptic properties of myenteric plexus neurones in the terminal large intestine of the guinea-pig

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Effect of Presynaptic P2Receptor Stimulation on Transmitter Release

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Histamine signals in enteric neuroimmune interactions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Fast excitatory postsynaptic potentials in AH (Type 2) neurons of guinea pig myenteric plexus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Observations on the algogenic actions of adenosine compounds on the human blister base preparation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Two types of neurones in the myenteric plexus of duodenum in the guinea-pig

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705761

The calcium-activated potassium conductance in guinea-pig myenteric neurones

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705761

ATP participates in three excitatory postsynaptic potentials in the submucous plexus of the guinea pig ileum.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectum

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Ileitis modulates potassium and sodium currents in guinea pig dorsal root ganglia sensory neurons

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Enhanced excitability of myenteric AH neurones in the inflamed guinea-pig distal colon

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Analysis of purinergic and cholinergic fast synaptic transmission to identified myenteric neurons.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Inhibitory interactions between 5-HT3 and P2X channels in submucosal neurons

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Neuroimmune interactions in guinea pig stomach and small intestine

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Neurochemical identification of enteric neurons expressing P2X(3) receptors in the guinea-pig ileum

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

ATP as a putative sensory mediator: activation of intrinsic sensory neurons of the myenteric plexus via P2X receptors.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

ATP and 5-HT are the principal neurotransmitters in the descending excitatory reflex pathway of the guinea-pig ileum.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

The distribution of purine P2X(2) receptors in the guinea-pig enteric nervous system

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

TNBS ileitis evokes hyperexcitability and changes in ionic membrane properties of nociceptive DRG neurons

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Morphological and functional alterations of the myenteric plexus in rats with TNBS-induced colitis

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Novel capsaicin (VR1) and purinergic (P2X3) receptors in Hirschsprung's intestine.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

ATP-gated ion channel P2X(3) is increased in human inflammatory bowel disease.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

IL-1beta and IL-6 excite neurones and suppress cholinergic neurotransmission in the myenteric plexus of the guinea pig.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Descending inhibitory reflexes involve P2X receptor-mediated transmission from interneurons to motor neurons in guinea-pig ileum

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Evidence that inhibitory motor neurons of the guinea-pig small intestine exhibit fast excitatory synaptic potentials mediated via P2X receptors.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Analysis of fast synaptic pathways in myenteric plexus of guinea pig ileum

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

ATP stimulates sympathetic transmitter release via presynaptic P2X purinoceptors.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Functional interactions between nicotinic and P2X channels in short-term cultures of guinea-pig submucosal neurons

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Projections of submucous neurons to the myenteric plexus in the guinea pig small intestine

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Glutamatergic enteric neurons.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Leukotriene-evoked cyclic chloride secretion is mediated by enteric neuronal modulation in guinea-pig colon

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574905

Modulation of the release of acetylcholine from ileal synaptosomes by adenosine and adenosine 5'-triphosphate

25 October 2018

1 reference

12 December 2020

Mucosal projections of enteric neurons in the porcine small intestine

1 reference

12 December 2020

All calbindin-immunoreactive myenteric neurons project to the mucosa of the guinea-pig small intestine

1 reference

12 December 2020

Postinfectious irritable bowel syndrome1 1Abbreviations used in this paper: EC,_; IBS, irritable bowel syndrome; PI, postinfective

1 reference

12 December 2020

Toxin B of Clostridium difficile activates human VIP submucosal neurons, in part via an IL-1beta-dependent pathway

1 reference

12 December 2020

Effects of inflammation on cell proliferation in the myenteric plexus of the guinea-pig ileum

1 reference

12 December 2020

Simultaneous intracellular recordings from enteric neurons reveal that myenteric ah neurons transmit via slow excitatory postsynaptic potentials

1 reference

12 December 2020

The complexity of drug development for irritable bowel syndrome

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705761

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.BJP.0705761

1 reference

6 August 2017

1 reference

6 August 2017

1 reference