(Q35026366)

5 August 2017

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title

Oxidative nucleotide damage: consequences and prevention (English)

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5 August 2017

Mutsuo Sekiguchi

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5 August 2017

Teruhisa Tsuzuki

series ordinal

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5 August 2017

language of work or name

English

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publication date

1 December 2002

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

8895-8904

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Altered base ratios in the DNA of an Escherichia coli mutator strain

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

Sequence-specific assignments of the backbone 1H, 13C, and 15N resonances of the MutT enzyme by heteronuclear multidimensional NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Solution structure of the MutT enzyme, a nucleoside triphosphate pyrophosphohydrolase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Molecular cloning and nucleotide sequence of the mutT mutator of Escherichia coli that causes A:T to C:G transversion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

A specific role of MutT protein: to prevent dG.dA mispairing in DNA replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Endogenous mutagens and the causes of aging and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Deficiency of 8-hydroxyguanine DNA endonuclease activity and accumulation of the 8-hydroxyguanine in mutator mutant (mutM) of Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

The oxidative DNA lesion 8,5'-(S)-cyclo-2'-deoxyadenosine is repaired by the nucleotide excision repair pathway and blocks gene expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

mutM, a second mutator locus in Escherichia coli that generates G.C----T.A transversions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

cDNA and genomic sequences for rat 8-oxo-dGTPase that prevents occurrence of spontaneous mutations due to oxidation of guanine nucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Repair of oxidative damage to DNA: enzymology and biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Mutational specificity of mice defective in the MTH1 and/or the MSH2 genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Thymine ring saturation and fragmentation products: lesion bypass, misinsertion and implications for mutagenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

NMR Studies of the Conformations and Location of Nucleotides Bound to the Escherichia coli MutT Enzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Functional significance of the conserved residues for the 23-residue module among MTH1 and MutT family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Genomic structure and chromosome location of the human mutT homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to C:G transversion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Modification of DNA bases in mammalian chromatin by radiation-generated free radicals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Metabolic fate of oxidized guanine ribonucleotides in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Generation and elimination of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate, a mutagenic substrate for DNA synthesis, in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Formation, prevention, and repair of DNA damage by iron/hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Organization and expression of the mouse MTH1 gene for preventing transversion mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Mouse MTH1 protein with 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphatase activity that prevents transversion mutation. cDNA cloning and tissue distribution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Sequence and characterization of mutT from Proteus vulgaris

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Potential of Escherichia coli GTP cyclohydrolase II for hydrolyzing 8-oxo-dGTP, a mutagenic substrate for DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

The role of Glu 57 in the mechanism of the Escherichia coli MutT enzyme by mutagenesis and heteronuclear NMR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Solution structure of the quaternary MutT-M2+-AMPCPP-M2+ complex and mechanism of its pyrophosphohydrolase action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

MutM, a protein that prevents G C→T A transversions, is formamidopyrimidine-DNA glycosylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

The fidelity of the human leading and lagging strand DNA replication apparatus with 8-oxodeoxyguanosine triphosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Mutational specificity of the dnaE173 mutator associated with a defect in the catalytic subunit of DNA polymerase III of Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

The mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Regulation of expression of the human MTH1 gene encoding 8-oxo-dGTPase. Alternative splicing of transcription products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Multi-forms of human MTH1 polypeptides produced by alternative translation initiation and single nucleotide polymorphism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Escherichia coli orf17 codes for a nucleoside triphosphate pyrophosphohydrolase member of the MutT family of proteins. Cloning, purification, and characterization of the enzyme.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Orf186 Represents a New Member of the Nudix Hydrolases, Active on Adenosine(5′)triphospho(5′)adenosine, ADP-ribose, and NADH

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Molecular cloning of AtMMH, an Arabidopsis thaliana ortholog of the Escherichia coli mutM gene, and analysis of functional domains of its product.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Strain dependent effects of sex hormones on hepatocarcinogenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

DNA replication fidelity with 8-oxodeoxyguanosine triphosphate.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Mechanisms of spontaneous mutagenesis: an analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Identification and characterization of the Nudix hydrolase from the Archaeon, Methanococcus jannaschii, as a highly specific ADP-ribose pyrophosphatase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Spontaneous mutagenesis: experimental, genetic and other factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

The onset and extent of genomic instability in sporadic colorectal tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Counteraction by MutT protein of transcriptional errors caused by oxidative damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Repair of DNA containing the oxidatively-damaged base, 8-oxoguanine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Reduction of Ribonucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

A Factor (or Mutator Gene) Influencing Mutation Rates in Escherichia Coli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Secondary structure of the MutT enzyme as determined by NMR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

The unusual mutagenic specificity of an E. Coli mutator gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206023

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206023

1 reference

5 August 2017

1 reference