(Q34752023)

4 August 2017

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title

New players and puzzles in the Hedgehog signaling pathway (English)

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4 August 2017

M P Scott

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4 August 2017

R L Johnson

series ordinal

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4 August 2017

publication date

1 August 1998

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Current Opinion in Genetics & Development

4 August 2017

published in

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4 August 2017

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4 August 2017

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4 August 2017

page(s)

450-456

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The Drosophila patched gene encodes a putative membrane protein required for segmental patterning

4 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Role of the Drosophila patched gene in positional signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Biochemical evidence that patched is the Hedgehog receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Hedgehog signaling regulates transcription through Gli/Ci binding sites in the wingless enhancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Dual roles for patched in sequestering and transducing Hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Altered neural cell fates and medulloblastoma in mouse patched mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Hedgehog and patched gene expression in adult ocular tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

GLI activates transcription through a herpes simplex viral protein 16-like activation domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Phosphorylation of the fused protein kinase in response to signaling from hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Dual pathways for induction of wingless expression by protein kinase A and Hedgehog in Drosophila embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Cholesterol modification of hedgehog signaling proteins in animal development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Recent advances in elucidating Niemann-Pick C disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Nevoid basal cell carcinoma syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Basal cell carcinomas in mice overexpressing sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Activating Smoothened mutations in sporadic basal-cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Primitive neuroectodermal tumors of the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Identification of an amplified, highly expressed gene in a human glioma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

Point mutations in human GLI3 cause Greig syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980117-2

7 January 2021

10.1016/S0959-437X(98)80117-2

Identifiers

DOI

1 reference

4 August 2017

1 reference