(Q34738743)

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The yeast TEL1 gene partially substitutes for human ATM in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in A-T cells

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Europe PubMed Central

PubMed publication ID

4 August 2017

The yeast TEL1 gene partially substitutes for human ATM in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in A-T cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Ralf Michael Zwacka

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author name string

E Fritz

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

A A Friedl

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

R M Zwacka

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

F Eckardt-Schupp

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

M S Meyn

5

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 August 2000

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Europe PubMed Central

PubMed publication ID

4 August 2017

Molecular Biology of the Cell

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Europe PubMed Central

PubMed publication ID

4 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

2605-2616

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Chromosomal breakage syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Genetic control of telomere integrity in Schizosaccharomyces pombe: rad3(+) and tel1(+) are parts of two regulatory networks independent of the downstream protein kinases chk1(+) and cds1(+).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Human fibroblasts transfected with an ATM antisense vector respond abnormally to ionizing radiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The influence of SV40 immortalization of human fibroblasts on p53-dependent radiation responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Defective modulation of double-strand break repair in ataxia telangiectasia cells by gamma radiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Defective control of apoptosis, radiosensitivity, and spindle checkpoint in ataxia telangiectasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

ATM: from gene to function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Regulation of Rad51 function by c-Abl in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Normal telomere maintenance in immortal ataxia telangiectasia cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Recombinant ATM protein complements the cellular A-T phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Interaction between ATM protein and c-Abl in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The genetic defect in ataxia-telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Fragments of ATM which have dominant-negative or complementing activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Overexpression of a truncated human topoisomerase III partially corrects multiple aspects of the ataxia-telangiectasia phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Regulation of p53 in response to ionizing radiation in ataxia telangiectasia fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Analysis of the ATM protein in wild-type and ataxia telangiectasia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The Schizosaccharomyces pombe rad3 checkpoint gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The Saccharomyces cerevisiae MEC1 gene, which encodes a homolog of the human ATM gene product, is required for G1 arrest following radiation treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Reduced telomere length in ataxia-telangiectasia fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Deregulated apoptosis in ataxia telangiectasia: association with clinical stigmata and radiosensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Ataxia-telangiectasia and cellular responses to DNA damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Telomere dynamics in an immortal human cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Genetic and cellular features of ataxia telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Testing the role of p53 in the expression of genetic instability and apoptosis in ataxia-telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Telomere elongation in immortal human cells without detectable telomerase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Expression cloning of multiple human cDNAs that complement the phenotypic defects of ataxia-telangiectasia group D fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Structural comparison of yeast ribosomal protein genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

A table for the estimation of the spontaneous mutations rate of cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Identification of yeast mutants with altered telomere structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Localization of an ataxia-telangiectasia gene to chromosome 11q22-23.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Hypersensitivity to cell killing and faulty repair of 1-beta-D-arabinofuranosylcytosine-detectable sites in human (ataxia-telangiectasia) fibroblasts treated with 4-nitroquinoline 1-oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Directional antisense and sense cDNA cloning using Epstein-Barr virus episomal expression vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Improved telomere detection using a telomere repeat probe (TTAGGG)n generated by PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The cytogenetics of ataxia telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

The rad3+ gene of Schizosaccharomyces pombe is involved in multiple checkpoint functions and in DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

7 July 2018

Telomere length dynamics in telomerase-positive immortal human cell populations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

26 October 2018

Predominance of null mutations in ataxia-telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

26 October 2018

A novel mechanism for telomere size control in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

26 October 2018

TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

26 October 2018

Accelerated telomere shortening in ataxia telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14943

9 December 2018

TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere Length Distribution and Southern Blot Analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEC1-dependent phosphorylation of Rad9p in response to DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of cell fate by c-Abl activation in the response to DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis and suppression of clonogenicity of ovarian carcinoma cells with estrogen mustard

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High frequencies of inversions and translocations of chromosomes 7 and 14 in ataxia telangiectasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comments on the paper: the ATM gene and the radiobiology of ataxia-telangiectasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of ATM function on telomere metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Testing the role of p53 in the expression of genetic instability and apoptosis in ataxia-telangiectasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.11.8.2605

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

ResearchGate publication ID

0 references

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