(Q34611857)

3 August 2017

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title

Mechanisms of ageing: public or private? (English)

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3 August 2017

Linda Partridge

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David Gems

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1 March 2002

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3 August 2017

published in

Nature Reviews Genetics

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

165-175

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The moulding of senescence by natural selection

3 August 2017

cites work

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Optimality, mutation and the evolution of ageing

31 March 2020

1 reference

Biogenesis of mitochondria

31 March 2020

1 reference

Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging rats

31 March 2020

1 reference

Oxidative damage and mutation to mitochondrial DNA and age-dependent decline of mitochondrial respiratory function

31 March 2020

1 reference

Aging and cancer: the double-edged sword of replicative senescence

31 March 2020

1 reference

31 March 2020

1 reference

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

31 March 2020

1 reference

The free radical theory of aging matures

31 March 2020

1 reference

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

31 March 2020

1 reference

Mortality oscillations induced by periodic starvation alter sex-mortality differentials in Mediterranean fruit flies

31 March 2020

1 reference

Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span

31 March 2020

1 reference

Short-term calorie restriction improves disease-related markers in older male rhesus monkeys (Macaca mulatta).

31 March 2020

1 reference

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

31 March 2020

1 reference

The evolution of the antiaging action of dietary restriction: a hypothesis

31 March 2020

1 reference

Food, reproduction and L'ongevity: Is the extended lifespan of calorie-restricted animals an evolutionary adaptation?

31 March 2020

1 reference

Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males.

31 March 2020

1 reference

The experimental manipulation of ageing by diet

31 March 2020

1 reference

Mammalian aging, metabolism, and ecology: evidence from the bats and marsupials

31 March 2020

1 reference

PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE

31 March 2020

1 reference

Extraordinary lifespans in ants: a test of evolutionary theories of ageing

31 March 2020

1 reference

Evolutionary theories of aging: confirmation of a fundamental prediction, with implications for the genetic basis and evolution of life span

31 March 2020

1 reference

Mutational order: a major stochastic process in evolution

31 March 2020

1 reference

A genetic analysis of senescence in Drosophila.

31 March 2020

1 reference

Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence

31 March 2020

1 reference

Ageing: levelling of the grim reaper.

31 March 2020

1 reference

DIRECT AND CORRELATED RESPONSES TO SELECTION ON AGE AT REPRODUCTION IN DROSOPHILA MELANOGASTER

31 March 2020

1 reference

Another set of responses and correlated responses to selection on age at reproduction in Drosophila melanogaster.

31 March 2020

1 reference

A delayed wave of death from reproduction in Drosophila.

31 March 2020

1 reference

A conserved regulatory system for aging

31 March 2020

1 reference

Insulin/IGF signalling and ageing: seeing the bigger picture

31 March 2020

1 reference

Delayed aging in Ames dwarf mice. Relationships to endocrine function and body size.

31 March 2020

1 reference

A C. elegans mutant that lives twice as long as wild type

31 March 2020

1 reference

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

31 March 2020

1 reference

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

31 March 2020

1 reference

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

31 March 2020

1 reference

Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family

31 March 2020

1 reference

Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span

31 March 2020

1 reference

Regulation of C. elegans life-span by insulinlike signaling in the nervous system

31 March 2020

1 reference

Regulation of lifespan by sensory perception in Caenorhabditis elegans

31 March 2020

1 reference

Signals from the reproductive system regulate the lifespan of C. elegans

31 March 2020

1 reference

A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span

31 March 2020

1 reference

The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans.

31 March 2020

1 reference

The genetics of caloric restriction in Caenorhabditis elegans

31 March 2020

1 reference

Longevity in Caenorhabditis elegans reduced by mating but not gamete production.

31 March 2020

1 reference

Molecular signals versus the Loi de Balancement

31 March 2020

1 reference

Evolution of germ-line signals that regulate growth and aging in nematodes

31 March 2020

1 reference

Evolution of lifespan in C. elegans.

31 March 2020

1 reference

Non-ageing developmental variant of Caenorhabditis elegans

31 March 2020

1 reference

The genetic control of organ growth: insights from Drosophila.

31 March 2020

1 reference

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

31 March 2020

1 reference

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

31 March 2020

1 reference

Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis

31 March 2020

1 reference

Evidence for a clade of nematodes, arthropods and other moulting animals

31 March 2020

1 reference

Homozygous nonsense mutation in the insulin receptor gene in infant with leprechaunism.

31 March 2020

1 reference

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

31 March 2020

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The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential

31 March 2020

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Dwarf mice and the ageing process.

31 March 2020

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Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

31 March 2020

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Fertility of transgenic female mice expressing bovine growth hormone or human growth hormone variant genes

31 March 2020

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Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models

31 March 2020

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A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

31 March 2020

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Is the Laron mouse an accurate model of Laron syndrome?

31 March 2020

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Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals

31 March 2020

1 reference

Extending the lifespan of long-lived mice

31 March 2020

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Evolution of senescence: late survival sacrificed for reproduction

31 March 2020

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Mutation-selection balance and the evolutionary advantage of sex and recombination

31 March 2020

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An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

31 March 2020

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Transgenic mice overexpressing urokinase-type plasminogen activator in the brain exhibit reduced food consumption, body weight and size, and increased longevity

31 March 2020

1 reference

The p66shc adaptor protein controls oxidative stress response and life span in mammals

31 March 2020

1 reference

Regulation of life-span by germ-line stem cells in Caenorhabditis elegans

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG753

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Dimensions Publication ID

3 August 2017

1006818470

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